UNE BIOCHEMISTRY 2026 TEST PAPER QUESTIONS AND
ANSWERS GUARANTEE A+
✔✔What sequence of enzyme allows for the synthesis of glycogen from glucose-6-
phosphate?
a.) Phsophoglucomutase, amylo-(1,4a1,6)-transglycosylase, UDP-glucose
pyrophosphorylase, glycogen synthase
b.) Phosphoglucomutase, UDP-glucose phosphorylase, glycogen synthase, amylo-
(1,4a1,6)-transglycosylase
c.) Phosphoglucomutase, UDP-glucose phosphorylase, amylo-(1,4a1,6)-
transglycosylase, glycogen phosphorylase
d.) UDP-glucose pyrophosporylase, phosphoglucomutase, glycogen synthase, amylo-
(1,4a1,6)-transglycosylase
e.) UDP-glucose pyrophosphorylase, phosphoglucomutase, amylo-(1,4a1,6)-
transglycosylase, glycogen synthase - ✔✔Phosphoglucomutase, UDP-glucose
phosphorylase, glycogen synthase, amylo-(1,4a1,6)-transglycosylase (B)
✔✔The process of gluconeogenesis primarily takes place in which of the following
tissue?
a.) Skeletal muscle
b.) Red blood cells
c.) Brain
d.) Liver - ✔✔Liver (D)
✔✔When the insulin to glucagon ratio is low, glycogenolysis is activated in the liver.
Which of the following is the primary fate of the glucose-6-phosphate released under
these conditions?
a.) Dephosphorylated and released into the blood to maintain blood glucose
b.) Released into the blood as glucose-6-phosphate
c.) Directly used as a substrate for gluconeogenesis
d.) Immediately converted to fructose-6-phosphate used as a substrate for glycolysis -
✔✔Dephosphorylated and released into the blood to maintain blood glucose (A)
, ✔✔Which of the following enzymes is correctly paired with its activator?
a.) Pyruvate kinase; citrate
b.) Glyceraldehyde 3-phoshpate dehydrogenase; citrate
c.) Pyruvate dehydrogenase complex; pyruvate
d.) Isocitrate dehydrogenase; NADH - ✔✔Pyruvate dehydrogenase complex; pyruvate
(C)
✔✔Which of the following are the 2 primary products of the pentose phosphate
pathway?
a.) ATP and NADPH
b.) Oxaloacetate and acetyl-CoA
c.) Sorbitol and fructose
d.) Ribose-5-phosphate and NADPH - ✔✔Ribose-5-phosphate and NADPH (D)
✔✔A family presents for genetic counseling. The couple has two female children who
are alive and well, however their infant son recently died in the nursery with severe
hemolysis and jaundice. The wife recalls she lost a brother in infancy with severe
hemolysis (rupturing of red blood cells), induced after a viral infection. The physician
suspects glucose-6-phosphate dehydrogenase deficiency, this would result in a
deficiency in which of the following compounds?
a.) Deoxyribose and NADP (nicotinamide adenine dinucleotide phosphate)
b.) Glucose and lactate
c.) Lactose and NADPH
d.) Ribose and NADPH
e.) Sucrose and NAD (nicotinamide adenine dinucleotide) - ✔✔Ribose and NADPH (D)
✔✔Which of the following is NOT stimulated by high levels of insulin?
a.) Fatty acid synthesis
b.) Glycolysis
ANSWERS GUARANTEE A+
✔✔What sequence of enzyme allows for the synthesis of glycogen from glucose-6-
phosphate?
a.) Phsophoglucomutase, amylo-(1,4a1,6)-transglycosylase, UDP-glucose
pyrophosphorylase, glycogen synthase
b.) Phosphoglucomutase, UDP-glucose phosphorylase, glycogen synthase, amylo-
(1,4a1,6)-transglycosylase
c.) Phosphoglucomutase, UDP-glucose phosphorylase, amylo-(1,4a1,6)-
transglycosylase, glycogen phosphorylase
d.) UDP-glucose pyrophosporylase, phosphoglucomutase, glycogen synthase, amylo-
(1,4a1,6)-transglycosylase
e.) UDP-glucose pyrophosphorylase, phosphoglucomutase, amylo-(1,4a1,6)-
transglycosylase, glycogen synthase - ✔✔Phosphoglucomutase, UDP-glucose
phosphorylase, glycogen synthase, amylo-(1,4a1,6)-transglycosylase (B)
✔✔The process of gluconeogenesis primarily takes place in which of the following
tissue?
a.) Skeletal muscle
b.) Red blood cells
c.) Brain
d.) Liver - ✔✔Liver (D)
✔✔When the insulin to glucagon ratio is low, glycogenolysis is activated in the liver.
Which of the following is the primary fate of the glucose-6-phosphate released under
these conditions?
a.) Dephosphorylated and released into the blood to maintain blood glucose
b.) Released into the blood as glucose-6-phosphate
c.) Directly used as a substrate for gluconeogenesis
d.) Immediately converted to fructose-6-phosphate used as a substrate for glycolysis -
✔✔Dephosphorylated and released into the blood to maintain blood glucose (A)
, ✔✔Which of the following enzymes is correctly paired with its activator?
a.) Pyruvate kinase; citrate
b.) Glyceraldehyde 3-phoshpate dehydrogenase; citrate
c.) Pyruvate dehydrogenase complex; pyruvate
d.) Isocitrate dehydrogenase; NADH - ✔✔Pyruvate dehydrogenase complex; pyruvate
(C)
✔✔Which of the following are the 2 primary products of the pentose phosphate
pathway?
a.) ATP and NADPH
b.) Oxaloacetate and acetyl-CoA
c.) Sorbitol and fructose
d.) Ribose-5-phosphate and NADPH - ✔✔Ribose-5-phosphate and NADPH (D)
✔✔A family presents for genetic counseling. The couple has two female children who
are alive and well, however their infant son recently died in the nursery with severe
hemolysis and jaundice. The wife recalls she lost a brother in infancy with severe
hemolysis (rupturing of red blood cells), induced after a viral infection. The physician
suspects glucose-6-phosphate dehydrogenase deficiency, this would result in a
deficiency in which of the following compounds?
a.) Deoxyribose and NADP (nicotinamide adenine dinucleotide phosphate)
b.) Glucose and lactate
c.) Lactose and NADPH
d.) Ribose and NADPH
e.) Sucrose and NAD (nicotinamide adenine dinucleotide) - ✔✔Ribose and NADPH (D)
✔✔Which of the following is NOT stimulated by high levels of insulin?
a.) Fatty acid synthesis
b.) Glycolysis
