Science Medicine Cardiology
BSNC 1000 - Module 4
Leave the first rating
Save
Students also studied
Final lectures Kin 101 Cardiovascular System: Component... Cardiovascular System - Drugs for ... Cardiov
30 terms 28 terms 47 terms 56 terms
chase_visser8 Preview Abdane_Gutema Preview zhangv18 Preview Win
Terms in this set (110)
- the flow of blood through arteries and capillaries delivering nutrients and oxygen
Perfusion to cells
- measured as blood flow per kilogram of unit mass (ml/min/kg)
- volume of blood pumped by the heart per minute
- radius of blood vessels
Factors affecting perfusion - viscosity of blood
- velocity of flow
- blood pressure
- generated by cardiac output
- the amount of blood pumped by the heart each minute
Central perfusion
- propels blood to all organs and their tissues from patent arteries through
capillaries and returns the blood to the heart through patent veins
- arterial blood pressure during ventricular systole
Systolic blood pressure
- numerator (top number)
- arterial blood pressure during ventricular diastole
Diastolic blood pressure
- denominator (bottom number)
- the difference between systolic and diastolic pressure
Pulse pressure
- around 40mmHg
- lies somewhere between systolic and diastolic
pressure
- influenced more by diastolic pressure than by
systolic pressure because the heart spends more
Mean arterial pressure
time in diastole than in systole
- rises to meet the bodies' metabolic demand
during periods of exertion.
- BP value of greatest clinical significance
Resting MAP - represents the force required to adequately perfuse the bodies' tissues at rest
, Identify (top to bottom)
Systolic, mean arterial pressure, diastolic
Formula for mean arterial pressure MAP = diastolic pressure + 1/3(pulse pressure)
Alternative formula for MAP MAP = cardiac output X total peripheral resistance
- expressed as systolic/diastolic
Blood pressure
- normal in a healthy, young adult is 120/80 mm Hg
Tissue perfusion - the volume of blood that flows through arteries and capillaries to target tissues
Arterial blood pressure - determined by cardiac output and systemic vascular resistance
- infarction
No perfusion
- tissue dies because there is no blood flow or nutrients
- ranges from optimal to impaired to no perfusion
- changes can be temporary, long term or permanent
Scope of perfusion - disorders that lead to changes can be acute or chronic
- conditions involving perfusion can be neurologic, pulmonary and cardiovascular
- caused by congenital defects, genetic disorders, injury, inflammation, and infections
- myocardial infarction
Examples of acute conditions - stroke
- shock
- hypertension
- heart failure
Examples of chronic conditions
- sickle cell
- hemophilia
- optimal blood flow and oxygen delivery to meet tissue demands
Optimal perfusion - not necessarily constant perfusion (it matches the need of the particular tissue -
e.g., low at rest and high during exercise)
- "ischemia" - reduction in blood flow
- cell/tissue injury
- occurs in conditions that decrease cardiac output or cause shock
Impaired perfusion
- associated with the occlusion, construction, or rupture of blood vessels
- any impairment in central perfusion will interfere with tissue perfusion
- often temporary, but there are cases where it gets progressively worse
- arrhythmia
- hypertension
Examples of impaired perfusion - myocardial infarction
- heart failure
- shock—anaphylactic, cardiogenic, or hemorrhagic
- "infarction"
No perfusion
- cell death
- age (risk increases with age)
- gender (men are more susceptible)
- genetics (family history, sickle cell disease, e.g., African Americans are more likely
Non-modifiable risk factors for perfusion
to get it )
- immobility (sitting in one position for a long time can interrupt blood flow in the
legs)
BSNC 1000 - Module 4
Leave the first rating
Save
Students also studied
Final lectures Kin 101 Cardiovascular System: Component... Cardiovascular System - Drugs for ... Cardiov
30 terms 28 terms 47 terms 56 terms
chase_visser8 Preview Abdane_Gutema Preview zhangv18 Preview Win
Terms in this set (110)
- the flow of blood through arteries and capillaries delivering nutrients and oxygen
Perfusion to cells
- measured as blood flow per kilogram of unit mass (ml/min/kg)
- volume of blood pumped by the heart per minute
- radius of blood vessels
Factors affecting perfusion - viscosity of blood
- velocity of flow
- blood pressure
- generated by cardiac output
- the amount of blood pumped by the heart each minute
Central perfusion
- propels blood to all organs and their tissues from patent arteries through
capillaries and returns the blood to the heart through patent veins
- arterial blood pressure during ventricular systole
Systolic blood pressure
- numerator (top number)
- arterial blood pressure during ventricular diastole
Diastolic blood pressure
- denominator (bottom number)
- the difference between systolic and diastolic pressure
Pulse pressure
- around 40mmHg
- lies somewhere between systolic and diastolic
pressure
- influenced more by diastolic pressure than by
systolic pressure because the heart spends more
Mean arterial pressure
time in diastole than in systole
- rises to meet the bodies' metabolic demand
during periods of exertion.
- BP value of greatest clinical significance
Resting MAP - represents the force required to adequately perfuse the bodies' tissues at rest
, Identify (top to bottom)
Systolic, mean arterial pressure, diastolic
Formula for mean arterial pressure MAP = diastolic pressure + 1/3(pulse pressure)
Alternative formula for MAP MAP = cardiac output X total peripheral resistance
- expressed as systolic/diastolic
Blood pressure
- normal in a healthy, young adult is 120/80 mm Hg
Tissue perfusion - the volume of blood that flows through arteries and capillaries to target tissues
Arterial blood pressure - determined by cardiac output and systemic vascular resistance
- infarction
No perfusion
- tissue dies because there is no blood flow or nutrients
- ranges from optimal to impaired to no perfusion
- changes can be temporary, long term or permanent
Scope of perfusion - disorders that lead to changes can be acute or chronic
- conditions involving perfusion can be neurologic, pulmonary and cardiovascular
- caused by congenital defects, genetic disorders, injury, inflammation, and infections
- myocardial infarction
Examples of acute conditions - stroke
- shock
- hypertension
- heart failure
Examples of chronic conditions
- sickle cell
- hemophilia
- optimal blood flow and oxygen delivery to meet tissue demands
Optimal perfusion - not necessarily constant perfusion (it matches the need of the particular tissue -
e.g., low at rest and high during exercise)
- "ischemia" - reduction in blood flow
- cell/tissue injury
- occurs in conditions that decrease cardiac output or cause shock
Impaired perfusion
- associated with the occlusion, construction, or rupture of blood vessels
- any impairment in central perfusion will interfere with tissue perfusion
- often temporary, but there are cases where it gets progressively worse
- arrhythmia
- hypertension
Examples of impaired perfusion - myocardial infarction
- heart failure
- shock—anaphylactic, cardiogenic, or hemorrhagic
- "infarction"
No perfusion
- cell death
- age (risk increases with age)
- gender (men are more susceptible)
- genetics (family history, sickle cell disease, e.g., African Americans are more likely
Non-modifiable risk factors for perfusion
to get it )
- immobility (sitting in one position for a long time can interrupt blood flow in the
legs)
