USMLE STEP 1 FIRST AID exam with
question and answer 100% correct
Name the disease associated most like associated with the following symptoms:
Abdominal Pain, Ascites, Hepatomegaly - Budd-Chiari syndrome (posthepatic venous
thrombosis)
Abdominal pain, diarrhea, leukocytosis, recent antibiotic use - Clostridium dificile
Name the disease associated most like associated with the following symptoms:
Achilles Tendon Xanthoma - Familial hypercholesteremia (Decreased LDL receptor signaling)
Adrenal Hemorrhage, hypotension, DIC - Waterhouse-Friedrichson Syndrome
(Meningicoccemia) Typical bacteria is Neisseria meningitidis
Anaphylaxis following a blood transfusion - IgA Deficiency
To note: The prevalence of celiac disease in patients with selective IgA deficiency ranges from
10% to 30%
Anterior "drawer sign" - Anterior cruciate ligament
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joins - Marfan syndrome
(fibrillin defect)
, FBN1 gene on chromosome 15 which encodes fibrillin-1, a glycoprotein component of the
extracellular matrix & sequestering transforming growth factor beta (TGF-β)
Athlete with polycytheme - Secondary to EPO injections
Back pain, fever, night sweats - Pott disease (vertebral TB)
Bilateral Acoustic Schwannomas - Neurofibromatosis 2
Bilateral hilar adenopathy, uveitis - Sarcoidosis (noncaseating granuloma)
Black eschar on on patient with diabetic ketoacidosis - Mucor or Rhizopus fungal infection
Blue sclera - Osteogenesis imperfecta (type I collagen defect)
Most cases are caused by mutations in the COL1A1 and COL1A2 genes.
Bluish line on gingiva - Burton line (lead poisoining)
Bone pain, bone enlargement, arthritis - Paget's Disease of Bone (increased osteoblastic
AND osteoclastic activity)
Paget's disease may be caused by a slow virus infection (i.e., paramyxoviridae) present for many
years before symptoms appear. Associated viral infections: RSV,
Paget's disease of bone also can be genetic: SQSTM1 and RANK, and specific regions of
chromosome 5 and 6.
question and answer 100% correct
Name the disease associated most like associated with the following symptoms:
Abdominal Pain, Ascites, Hepatomegaly - Budd-Chiari syndrome (posthepatic venous
thrombosis)
Abdominal pain, diarrhea, leukocytosis, recent antibiotic use - Clostridium dificile
Name the disease associated most like associated with the following symptoms:
Achilles Tendon Xanthoma - Familial hypercholesteremia (Decreased LDL receptor signaling)
Adrenal Hemorrhage, hypotension, DIC - Waterhouse-Friedrichson Syndrome
(Meningicoccemia) Typical bacteria is Neisseria meningitidis
Anaphylaxis following a blood transfusion - IgA Deficiency
To note: The prevalence of celiac disease in patients with selective IgA deficiency ranges from
10% to 30%
Anterior "drawer sign" - Anterior cruciate ligament
Arachnodactyly, lens dislocation, aortic dissection, hyperflexible joins - Marfan syndrome
(fibrillin defect)
, FBN1 gene on chromosome 15 which encodes fibrillin-1, a glycoprotein component of the
extracellular matrix & sequestering transforming growth factor beta (TGF-β)
Athlete with polycytheme - Secondary to EPO injections
Back pain, fever, night sweats - Pott disease (vertebral TB)
Bilateral Acoustic Schwannomas - Neurofibromatosis 2
Bilateral hilar adenopathy, uveitis - Sarcoidosis (noncaseating granuloma)
Black eschar on on patient with diabetic ketoacidosis - Mucor or Rhizopus fungal infection
Blue sclera - Osteogenesis imperfecta (type I collagen defect)
Most cases are caused by mutations in the COL1A1 and COL1A2 genes.
Bluish line on gingiva - Burton line (lead poisoining)
Bone pain, bone enlargement, arthritis - Paget's Disease of Bone (increased osteoblastic
AND osteoclastic activity)
Paget's disease may be caused by a slow virus infection (i.e., paramyxoviridae) present for many
years before symptoms appear. Associated viral infections: RSV,
Paget's disease of bone also can be genetic: SQSTM1 and RANK, and specific regions of
chromosome 5 and 6.
