Chamberlain University
NR 546 / NR546
Week 4
Anxiolytic Table
Course: Advanced Pharmacology
Downloaded by Benjamin Luca ()
, lOMoARcPSD|51648332
Anxiolytic
Medications
Drug Indication Associated Halḟ-liḟe (T1/2) Notable side eḟḟects
Name/ list diagnosis and Neurotransmit Metabolism (CYP
Medicatio targeted symptoms ters 450 enzyme)
n class
Gabapentin Partial seizures Binds to the Halḟ-Liḟe Sedation, dizziness
Postherpetic alpha 2 delta 5-7 hrs. Ataxia, ḟatigue, nystagmus,
neuralgia subunit oḟ Metabolism tremor Peripheral edema
Restless leg voltage- ● Does not Blurred vision
syndrome sensitive metabolize but Vomiting, dyspepsia, diarrhea,
Neuropathic pain/ calcium excreted intact dry mouth, constipation, weight
chronic pain
Bipolar disorder channels renally gain
Additional eḟḟects in children under
12:
hostility, emotional lability,
hyperkinesia,
thought disorder, weight gain
Pregabalin Diabetic Binds to the Halḟ-Liḟe Sedation, dizziness
peripheral alpha 2 delta ● 5-7 Ataxia, ḟatigue, tremor,
neuropathy subunit oḟ hours dysarthria, paresthesia,
Postherpetic voltage- Metabolism memory impairment,
neuralgia sensitive ● Pregabalin is coordination abnormal,
Ḟibromyalgia calcium not impaired attention,
Neuropathic pain channels metabolized conḟusion, euphoric mood,
associated with but excreted irritability
Partial onset intact renally weight gain, increased appetite,
seizures
in adults and ḟlatulence
pediatric
patients Blurred vision, diplopia
Peripheral Peripheral Edema
neuropathic pain Libido decreased, erectile
GAD dysḟunction
Panic disorder
Social anxiety
Buspirone disorder
Major Boost Halḟ liḟe Dry mouth, constipation,
depressive neurotransmit ● Parent: 10-14 Hrs. nausea, weight loss, anorexia,
disorder ter ● Metabolite: myalgia
Seasonal norepinephrin 20- 27Hrs. Insomnia, dizziness, headache,
aḟḟective e/n Metabolism agitation, anxiety, tremor,
disorder oradrenaline CYP450 2D6 abdominal pain, tinnitus
Nicotine
Attention deḟicit and
Blocks Sweating
Hypertension
hyperactivity norepinephrine
disorder
(ADHD) reuptake pump,
Sexual Dysḟunction presumably
increasing
NR 546 / NR546
Week 4
Anxiolytic Table
Course: Advanced Pharmacology
Downloaded by Benjamin Luca ()
, lOMoARcPSD|51648332
Anxiolytic
Medications
Drug Indication Associated Halḟ-liḟe (T1/2) Notable side eḟḟects
Name/ list diagnosis and Neurotransmit Metabolism (CYP
Medicatio targeted symptoms ters 450 enzyme)
n class
Gabapentin Partial seizures Binds to the Halḟ-Liḟe Sedation, dizziness
Postherpetic alpha 2 delta 5-7 hrs. Ataxia, ḟatigue, nystagmus,
neuralgia subunit oḟ Metabolism tremor Peripheral edema
Restless leg voltage- ● Does not Blurred vision
syndrome sensitive metabolize but Vomiting, dyspepsia, diarrhea,
Neuropathic pain/ calcium excreted intact dry mouth, constipation, weight
chronic pain
Bipolar disorder channels renally gain
Additional eḟḟects in children under
12:
hostility, emotional lability,
hyperkinesia,
thought disorder, weight gain
Pregabalin Diabetic Binds to the Halḟ-Liḟe Sedation, dizziness
peripheral alpha 2 delta ● 5-7 Ataxia, ḟatigue, tremor,
neuropathy subunit oḟ hours dysarthria, paresthesia,
Postherpetic voltage- Metabolism memory impairment,
neuralgia sensitive ● Pregabalin is coordination abnormal,
Ḟibromyalgia calcium not impaired attention,
Neuropathic pain channels metabolized conḟusion, euphoric mood,
associated with but excreted irritability
Partial onset intact renally weight gain, increased appetite,
seizures
in adults and ḟlatulence
pediatric
patients Blurred vision, diplopia
Peripheral Peripheral Edema
neuropathic pain Libido decreased, erectile
GAD dysḟunction
Panic disorder
Social anxiety
Buspirone disorder
Major Boost Halḟ liḟe Dry mouth, constipation,
depressive neurotransmit ● Parent: 10-14 Hrs. nausea, weight loss, anorexia,
disorder ter ● Metabolite: myalgia
Seasonal norepinephrin 20- 27Hrs. Insomnia, dizziness, headache,
aḟḟective e/n Metabolism agitation, anxiety, tremor,
disorder oradrenaline CYP450 2D6 abdominal pain, tinnitus
Nicotine
Attention deḟicit and
Blocks Sweating
Hypertension
hyperactivity norepinephrine
disorder
(ADHD) reuptake pump,
Sexual Dysḟunction presumably
increasing
