NSG 6005
Pharmacology
Week 1-5 Exam
Actual Qs & Ans to Pass the Exam
THIS EXAM CONSIST OF
➢ Questions covering NSG 6005 week 5
➢ multiple-choice format (A, B, C, D) with Correct Answers
➢ Some questions feature brief "scenario" elements and rationales
➢ 150+ Questions with 100% Correct Answers
,1. The major reason for not crushing a sustained release capsule is that, if crushed, the coated
beads of the drugs could possibly result in:
A. Disintegration
B. Toxicity
C. Malabsorption
D. Deterioration
• Correct Answer – B. Toxicity
Rationale: Sustained-release capsules are designed to release medication gradually.
Crushing them disrupts the coating, leading to rapid absorption and dangerously high
serum drug levels.
2. Drugs that have a significant first-pass effect:
A. Must be given by enteral (oral) route only
B. Bypass the hepatic circulation
C. Are rapidly metabolized by the liver and may have little if any desired action
D. Are converted by the liver to more active fat-soluble forms
• Correct Answer – C. Are rapidly metabolized by the liver and may have little if any
desired action
Rationale: Drugs with a strong first-pass effect undergo extensive hepatic metabolism
before reaching systemic circulation, reducing their bioavailability when given orally.
3. When obtaining a drug history from Harold, he gives you a complete list of his prescription
medications. He denies taking any other drugs, but you find that he occasionally takes aspirin
for his arthritis flare-ups. This is an example of:
A. His appropriately only telling you about his regularly prescribed medications
B. His hiding information regarding his inappropriate use of aspirin from you
C. His common misconception that intermittently taking OTC medications are not an important
part of his drug history
D. A common misuse of OTC aspirin
, • Correct Answer – C. His common misconception that intermittently taking OTC
medications are not an important part of his drug history
Rationale: Patients often fail to report OTC or herbal drugs, mistakenly believing they are
irrelevant, which can cause drug–drug interactions and affect prescribing decisions.
4. Drugs that use CYP3A4 isoenzymes for metabolism may:
A. Induce the metabolism of another drug
B. Inhibit the metabolism of another drug
C. Both A and B
D. Neither A nor B
• Correct Answer – C. Both A and B
Rationale: CYP3A4 is involved in the metabolism of many drugs. Enzyme induction can
lower therapeutic effect, while inhibition can increase toxicity risk.
5. A twenty-four-year-old male received multiple fractures in a motor vehicle accident that
required significant amounts of opioid medication to treat his pain. He is at risk for Type ____
ADR when he no longer requires the opioids.
A. Type A
B. Type C
C. Type E
D. Type G
• Correct Answer – C. Type E
Rationale: Type E (end-of-use) adverse drug reactions occur with drug withdrawal, such
as opioid withdrawal symptoms when opioids are abruptly discontinued.
6. Infants and young children are at higher risk of ADRs due to:
A. Immature renal function in school-age children
B. Lack of safety and efficacy studies in the pediatric population
C. Children’s skin being thicker than adults, requiring higher dosages of topical medication
D. Infant boys having a higher proportion of muscle mass, leading to a higher volume of
distribution
, • Correct Answer – B. Lack of safety and efficacy studies in the pediatric population
Rationale: Pediatric dosing is complicated by limited clinical trials in children, making
safety and efficacy data less robust. This increases ADR risk.
7. The type of ADR that is the result of an unwanted but otherwise normal pharmacological
action of a drug given in the usual therapeutic dose is:
A. Type A
B. Type B
C. Type C
D. Type D
• Correct Answer – A. Type A
Rationale: Type A reactions are predictable, dose-dependent, and related to the drug’s
known pharmacological effect (e.g., hypotension from antihypertensives).
8. A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old because:
A. Drugs given in liquid form are less irritating to the stomach
B. A six-year-old may have problems swallowing a pill
C. Liquid forms of medication eliminate the concern for first-pass effect
D. Liquid ibuprofen does not have to be dosed as often as tablet form
• Correct Answer – B. A six-year-old may have problems swallowing a pill
Rationale: Children under 8 years often have difficulty swallowing tablets, so liquid
formulations improve adherence and safe administration.
9. The role of the nurse practitioner in the use of herbal medication is to:
A. Maintain competence in the prescribing of common herbal remedies
B. Recommend common OTC herbs to patients
C. Educate patients and guide them to appropriate sources of care
D. Encourage patients to not use herbal therapy due to the documented dangers
• Correct Answer – C. Educate patients and guide them to appropriate sources of care
Rationale: NPs should not prescribe herbs directly but must assess use, provide
education, identify potential interactions, and guide safe decision-making.
Pharmacology
Week 1-5 Exam
Actual Qs & Ans to Pass the Exam
THIS EXAM CONSIST OF
➢ Questions covering NSG 6005 week 5
➢ multiple-choice format (A, B, C, D) with Correct Answers
➢ Some questions feature brief "scenario" elements and rationales
➢ 150+ Questions with 100% Correct Answers
,1. The major reason for not crushing a sustained release capsule is that, if crushed, the coated
beads of the drugs could possibly result in:
A. Disintegration
B. Toxicity
C. Malabsorption
D. Deterioration
• Correct Answer – B. Toxicity
Rationale: Sustained-release capsules are designed to release medication gradually.
Crushing them disrupts the coating, leading to rapid absorption and dangerously high
serum drug levels.
2. Drugs that have a significant first-pass effect:
A. Must be given by enteral (oral) route only
B. Bypass the hepatic circulation
C. Are rapidly metabolized by the liver and may have little if any desired action
D. Are converted by the liver to more active fat-soluble forms
• Correct Answer – C. Are rapidly metabolized by the liver and may have little if any
desired action
Rationale: Drugs with a strong first-pass effect undergo extensive hepatic metabolism
before reaching systemic circulation, reducing their bioavailability when given orally.
3. When obtaining a drug history from Harold, he gives you a complete list of his prescription
medications. He denies taking any other drugs, but you find that he occasionally takes aspirin
for his arthritis flare-ups. This is an example of:
A. His appropriately only telling you about his regularly prescribed medications
B. His hiding information regarding his inappropriate use of aspirin from you
C. His common misconception that intermittently taking OTC medications are not an important
part of his drug history
D. A common misuse of OTC aspirin
, • Correct Answer – C. His common misconception that intermittently taking OTC
medications are not an important part of his drug history
Rationale: Patients often fail to report OTC or herbal drugs, mistakenly believing they are
irrelevant, which can cause drug–drug interactions and affect prescribing decisions.
4. Drugs that use CYP3A4 isoenzymes for metabolism may:
A. Induce the metabolism of another drug
B. Inhibit the metabolism of another drug
C. Both A and B
D. Neither A nor B
• Correct Answer – C. Both A and B
Rationale: CYP3A4 is involved in the metabolism of many drugs. Enzyme induction can
lower therapeutic effect, while inhibition can increase toxicity risk.
5. A twenty-four-year-old male received multiple fractures in a motor vehicle accident that
required significant amounts of opioid medication to treat his pain. He is at risk for Type ____
ADR when he no longer requires the opioids.
A. Type A
B. Type C
C. Type E
D. Type G
• Correct Answer – C. Type E
Rationale: Type E (end-of-use) adverse drug reactions occur with drug withdrawal, such
as opioid withdrawal symptoms when opioids are abruptly discontinued.
6. Infants and young children are at higher risk of ADRs due to:
A. Immature renal function in school-age children
B. Lack of safety and efficacy studies in the pediatric population
C. Children’s skin being thicker than adults, requiring higher dosages of topical medication
D. Infant boys having a higher proportion of muscle mass, leading to a higher volume of
distribution
, • Correct Answer – B. Lack of safety and efficacy studies in the pediatric population
Rationale: Pediatric dosing is complicated by limited clinical trials in children, making
safety and efficacy data less robust. This increases ADR risk.
7. The type of ADR that is the result of an unwanted but otherwise normal pharmacological
action of a drug given in the usual therapeutic dose is:
A. Type A
B. Type B
C. Type C
D. Type D
• Correct Answer – A. Type A
Rationale: Type A reactions are predictable, dose-dependent, and related to the drug’s
known pharmacological effect (e.g., hypotension from antihypertensives).
8. A nurse practitioner would prescribe the liquid form of ibuprofen for a six-year-old because:
A. Drugs given in liquid form are less irritating to the stomach
B. A six-year-old may have problems swallowing a pill
C. Liquid forms of medication eliminate the concern for first-pass effect
D. Liquid ibuprofen does not have to be dosed as often as tablet form
• Correct Answer – B. A six-year-old may have problems swallowing a pill
Rationale: Children under 8 years often have difficulty swallowing tablets, so liquid
formulations improve adherence and safe administration.
9. The role of the nurse practitioner in the use of herbal medication is to:
A. Maintain competence in the prescribing of common herbal remedies
B. Recommend common OTC herbs to patients
C. Educate patients and guide them to appropriate sources of care
D. Encourage patients to not use herbal therapy due to the documented dangers
• Correct Answer – C. Educate patients and guide them to appropriate sources of care
Rationale: NPs should not prescribe herbs directly but must assess use, provide
education, identify potential interactions, and guide safe decision-making.
