Page | 1
ATI Pharmacology Proctored Exam 2025–2026 Test
Bank | 200 Verified Questions with Correct Answers
& Rationales | Graded A+ | Latest Update
✅ 1. A nurse is preparing to administer digoxin to a client. Which of the
following actions should the nurse take prior to administration?
A. Measure the client’s blood glucose
B. Check the client's apical pulse for 1 full minute
C. Assess the client's level of consciousness
D. Evaluate the client’s oxygen saturation
✅ Correct Answer: B
Rationale: Digoxin slows heart rate. The apical pulse should be checked for a full minute, and
the medication held if the rate is below 60 bpm.
✅ 2. A client receiving furosemide is at risk for which of the following
electrolyte imbalances?
A. Hypernatremia
B. Hyperkalemia
C. Hypokalemia
D. Hypocalcemia
✅ Correct Answer: C
Rationale: Furosemide is a loop diuretic that promotes potassium excretion, leading to
hypokalemia.
, ✅ 3. A nurse is providing teaching to a client taking warfarin. Which food
should the nurse advise the client to avoid?
A. Bananas
B. Milk
Page | 2 C. Spinach
D. Apples
✅ Correct Answer: C
Rationale: Spinach is high in vitamin K, which antagonizes the effects of warfarin, reducing
its efficacy.
✅ 4. A client with asthma is prescribed albuterol. The nurse should monitor for
which adverse effect?
A. Bradycardia
B. Hypotension
C. Tachycardia
D. Respiratory depression
✅ Correct Answer: C
Rationale: Albuterol can cause beta-agonist effects, including tachycardia and palpitations.
✅ 5. What is a common side effect of opioid analgesics like morphine?
A. Constipation
B. Diarrhea
C. Increased urine output
D. Hyperactivity
✅ Correct Answer: A
Rationale: Opioids slow gastrointestinal motility, often resulting in constipation.
✅ 6. Which lab value should be monitored for a client taking lithium?
A. Blood glucose
B. Hematocrit
C. BUN
D. Serum sodium
✅ Correct Answer: D
Rationale: Lithium toxicity is increased with low sodium levels, so serum sodium must be
monitored.
, ✅ 7. What is an early sign of gentamicin toxicity?
A. Tinnitus
Page | 3 B. Drowsiness
C. Constipation
D. Blurred vision
✅ Correct Answer: A
Rationale: Gentamicin can be ototoxic, and tinnitus is often an early warning sign of toxicity.
✅ 8. A nurse is reviewing a prescription for a client receiving isoniazid for
tuberculosis. Which supplement should be administered concurrently?
A. Iron
B. Calcium
C. Vitamin C
D. Vitamin B6 (pyridoxine)
✅ Correct Answer: D
Rationale: Isoniazid may cause peripheral neuropathy, which is prevented by administering
vitamin B6.
✅ 9. Which client statement indicates understanding of how to use a
nitroglycerin sublingual tablet?
A. “I should swallow the tablet whole.”
B. “I can take as many tablets as needed.”
C. “I should place the tablet under my tongue until it dissolves.”
D. “I should chew the tablet before swallowing.”
✅ Correct Answer: C
Rationale: Sublingual nitroglycerin must be dissolved under the tongue for rapid absorption.
✅ 10. Which medication should be avoided in a client with a sulfa allergy?
A. Furosemide
B. Acetaminophen
C. Ibuprofen
D. Ciprofloxacin
✅ Correct Answer: A
, Rationale: Furosemide is a sulfonamide derivative and can cause hypersensitivity in clients
allergic to sulfa drugs.
Page | 4 ✅ 11. What adverse effect is associated with amiodarone?
A. Alopecia
B. Bradykinesia
C. Pulmonary toxicity
D. Urinary retention
✅ Correct Answer: C
Rationale: Amiodarone can cause serious pulmonary complications, including fibrosis.
✅ 12. Which lab value must be monitored for a client taking warfarin?
A. aPTT
B. INR
C. PT/INR
D. Platelets
✅ Correct Answer: C
Rationale: PT/INR is the primary lab used to monitor warfarin therapy effectiveness and
safety.
✅ 13. Which of the following is a priority assessment for a client starting
captopril?
A. Blood pressure
B. Heart rate
C. Respiratory rate
D. Temperature
✅ Correct Answer: A
Rationale: Captopril is an ACE inhibitor that can cause hypotension, especially with the first
dose.
✅ 14. A nurse is teaching a client about levothyroxine. Which statement
indicates understanding?
ATI Pharmacology Proctored Exam 2025–2026 Test
Bank | 200 Verified Questions with Correct Answers
& Rationales | Graded A+ | Latest Update
✅ 1. A nurse is preparing to administer digoxin to a client. Which of the
following actions should the nurse take prior to administration?
A. Measure the client’s blood glucose
B. Check the client's apical pulse for 1 full minute
C. Assess the client's level of consciousness
D. Evaluate the client’s oxygen saturation
✅ Correct Answer: B
Rationale: Digoxin slows heart rate. The apical pulse should be checked for a full minute, and
the medication held if the rate is below 60 bpm.
✅ 2. A client receiving furosemide is at risk for which of the following
electrolyte imbalances?
A. Hypernatremia
B. Hyperkalemia
C. Hypokalemia
D. Hypocalcemia
✅ Correct Answer: C
Rationale: Furosemide is a loop diuretic that promotes potassium excretion, leading to
hypokalemia.
, ✅ 3. A nurse is providing teaching to a client taking warfarin. Which food
should the nurse advise the client to avoid?
A. Bananas
B. Milk
Page | 2 C. Spinach
D. Apples
✅ Correct Answer: C
Rationale: Spinach is high in vitamin K, which antagonizes the effects of warfarin, reducing
its efficacy.
✅ 4. A client with asthma is prescribed albuterol. The nurse should monitor for
which adverse effect?
A. Bradycardia
B. Hypotension
C. Tachycardia
D. Respiratory depression
✅ Correct Answer: C
Rationale: Albuterol can cause beta-agonist effects, including tachycardia and palpitations.
✅ 5. What is a common side effect of opioid analgesics like morphine?
A. Constipation
B. Diarrhea
C. Increased urine output
D. Hyperactivity
✅ Correct Answer: A
Rationale: Opioids slow gastrointestinal motility, often resulting in constipation.
✅ 6. Which lab value should be monitored for a client taking lithium?
A. Blood glucose
B. Hematocrit
C. BUN
D. Serum sodium
✅ Correct Answer: D
Rationale: Lithium toxicity is increased with low sodium levels, so serum sodium must be
monitored.
, ✅ 7. What is an early sign of gentamicin toxicity?
A. Tinnitus
Page | 3 B. Drowsiness
C. Constipation
D. Blurred vision
✅ Correct Answer: A
Rationale: Gentamicin can be ototoxic, and tinnitus is often an early warning sign of toxicity.
✅ 8. A nurse is reviewing a prescription for a client receiving isoniazid for
tuberculosis. Which supplement should be administered concurrently?
A. Iron
B. Calcium
C. Vitamin C
D. Vitamin B6 (pyridoxine)
✅ Correct Answer: D
Rationale: Isoniazid may cause peripheral neuropathy, which is prevented by administering
vitamin B6.
✅ 9. Which client statement indicates understanding of how to use a
nitroglycerin sublingual tablet?
A. “I should swallow the tablet whole.”
B. “I can take as many tablets as needed.”
C. “I should place the tablet under my tongue until it dissolves.”
D. “I should chew the tablet before swallowing.”
✅ Correct Answer: C
Rationale: Sublingual nitroglycerin must be dissolved under the tongue for rapid absorption.
✅ 10. Which medication should be avoided in a client with a sulfa allergy?
A. Furosemide
B. Acetaminophen
C. Ibuprofen
D. Ciprofloxacin
✅ Correct Answer: A
, Rationale: Furosemide is a sulfonamide derivative and can cause hypersensitivity in clients
allergic to sulfa drugs.
Page | 4 ✅ 11. What adverse effect is associated with amiodarone?
A. Alopecia
B. Bradykinesia
C. Pulmonary toxicity
D. Urinary retention
✅ Correct Answer: C
Rationale: Amiodarone can cause serious pulmonary complications, including fibrosis.
✅ 12. Which lab value must be monitored for a client taking warfarin?
A. aPTT
B. INR
C. PT/INR
D. Platelets
✅ Correct Answer: C
Rationale: PT/INR is the primary lab used to monitor warfarin therapy effectiveness and
safety.
✅ 13. Which of the following is a priority assessment for a client starting
captopril?
A. Blood pressure
B. Heart rate
C. Respiratory rate
D. Temperature
✅ Correct Answer: A
Rationale: Captopril is an ACE inhibitor that can cause hypotension, especially with the first
dose.
✅ 14. A nurse is teaching a client about levothyroxine. Which statement
indicates understanding?
