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Basic-and-Clinical-Pharmacology-14th-Edition-Katzung-Trevor-Test- Bank
BASIC AND CLINICAL PHARMACOLOGY 14th
- - - - -
EDITION KATZUNG TREVOR Test Bank
- - - -
Chapter-1.-Introduction:-The-Nature-of-Drugs-&-Drug-Development-&-Regulation
1. A-nurse-working-in-radiology-administers-iodine-to-a-patient-who-is-having-a-
computed-tomography-(CT)-scan.-The-nurse-working-on-the-oncology-unit-
administers-chemotherapy-to-patients-who-have-cancer.-At-the-Public-Health-
Department,-a-nurse-administers-a-measles-mumps-rubella-(MMR)-vaccine-to-
a-14-month-old-child-as-a-routine-immunization.-Which-branch-of-
pharmacology-best-describes-the-actions-of-all-three- nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology-is-the-study-of-the-biologic-effects-of-chemicals.-Nurses-are-
involved-with-clinical-pharmacology-or-pharmacotherapeutics,-which-is-a-
branch-of-pharmacology-that-deals-with-the-uses-of-drugs-to-treat,-prevent,-
and-diagnose-disease.-The-radiology-nurse-is-administering-a-drug-to-help-
diagnose-a-disease.-The-oncology-nurse-is-administering-a-drug-to-help-treat-a-
disease.-Pharmacoeconomics-includes-any-costs-involved-in-drug-therapy.
Pharmacodynamics-involves-how-a-drug-affects-the-body-and-
pharmacokinetics-is-how-the-body-acts-on-the-body.
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2. A-physician-has-ordered-intramuscular-(IM)-injections-of-morphine,-a-
narcotic,-every-4-hours-as-needed-for-pain-in-a-motor-vehicle-accident-victim.-
The-nurse-is-aware-this-drug-has-a-high-abuse-potential.-Under-what-category-
would-morphine-be-classified?
A) Schedule-I
B) Schedule-II
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C) Schedule-III
D) Schedule-IV
Ans: B
Feedback:
Narcotics-with-a-high-abuse-potential-are-classified-as-Schedule-II-drugs-
because-of-severe-dependence-liability.-Schedule-I-drugs-have-high-abuse-
potential-and-no-accepted-medical-use.-Schedule-III-drugs-have-a-lesser-
abuse-potential-than-II-and-an-accepted-medical-use.-Schedule-IV-drugs-have-
low-abuse-potential-and-limited-dependence-liability.
3. When-involved-in-phase-III-drug-evaluation-studies,-what-responsibilities-
would-the-nurse-have?
A) Working-with-animals-who-are-given-experimental- drugs
B) Choosing-appropriate-patients-to-be-involved-in-the-drug- study
C) Monitoring-and-observing-patients-closely-for-adverse- effects
D) Conducting-research-to-determine-effectiveness-of-the- drug
Ans: C
Feedback:
Phase-III-studies-involve-use-of-a-drug-in-a-vast-clinical-population-in-which-
patients-are-asked-to-record-any-symptoms-they-experience-while-taking-the-
drugs.-Nurses-may-be-responsible-for-helping-collect-and-analyze-the-
information-to-be-shared-with-the-Food-and-Drug-Administration-(FDA)-but-
would-not-conduct-research-independently-because-nurses-do-not-prescribe-
medications.-Use-of-animals-in-drug-testing-is-done-in-the-preclinical-trials.-
Select-patients-who-are-involved-in-phase-II-studies-to-participate-in-studies-
where-the-participants-have-the-disease-the-drug-is-intended-to-treat.-These-
patients-are-monitored-closely-for-drug-action-and-adverse-effects.-Phase-I-
studies-involve-healthy-human-volunteers-who-are-usually-paid-for-their-
participation.-Nurses-may-observe-for-adverse-effects-and-toxicity.
4. What-concept-is-considered-when-generic-drugs-are-substituted-for-brand-
name-drugs?
A) Bioavailability
, Page-2-of-824
Basic-and-Clinical-Pharmacology-14th-Edition-Katzung-Trevor-Test- Bank
BASIC AND CLINICAL PHARMACOLOGY 14th
- - - - -
EDITION KATZUNG TREVOR Test Bank
- - - -
Chapter-1.-Introduction:-The-Nature-of-Drugs-&-Drug-Development-&-Regulation
1. A-nurse-working-in-radiology-administers-iodine-to-a-patient-who-is-having-a-
computed-tomography-(CT)-scan.-The-nurse-working-on-the-oncology-unit-
administers-chemotherapy-to-patients-who-have-cancer.-At-the-Public-Health-
Department,-a-nurse-administers-a-measles-mumps-rubella-(MMR)-vaccine-to-
a-14-month-old-child-as-a-routine-immunization.-Which-branch-of-
pharmacology-best-describes-the-actions-of-all-three- nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology-is-the-study-of-the-biologic-effects-of-chemicals.-Nurses-are-
involved-with-clinical-pharmacology-or-pharmacotherapeutics,-which-is-a-
branch-of-pharmacology-that-deals-with-the-uses-of-drugs-to-treat,-prevent,-
and-diagnose-disease.-The-radiology-nurse-is-administering-a-drug-to-help-
diagnose-a-disease.-The-oncology-nurse-is-administering-a-drug-to-help-treat-a-
disease.-Pharmacoeconomics-includes-any-costs-involved-in-drug-therapy.
Pharmacodynamics-involves-how-a-drug-affects-the-body-and-
pharmacokinetics-is-how-the-body-acts-on-the-body.
, Page-3-of-824
2. A-physician-has-ordered-intramuscular-(IM)-injections-of-morphine,-a-
narcotic,-every-4-hours-as-needed-for-pain-in-a-motor-vehicle-accident-victim.-
The-nurse-is-aware-this-drug-has-a-high-abuse-potential.-Under-what-category-
would-morphine-be-classified?
A) Schedule-I
B) Schedule-II
, Page-4-of-824
C) Schedule-III
D) Schedule-IV
Ans: B
Feedback:
Narcotics-with-a-high-abuse-potential-are-classified-as-Schedule-II-drugs-
because-of-severe-dependence-liability.-Schedule-I-drugs-have-high-abuse-
potential-and-no-accepted-medical-use.-Schedule-III-drugs-have-a-lesser-
abuse-potential-than-II-and-an-accepted-medical-use.-Schedule-IV-drugs-have-
low-abuse-potential-and-limited-dependence-liability.
3. When-involved-in-phase-III-drug-evaluation-studies,-what-responsibilities-
would-the-nurse-have?
A) Working-with-animals-who-are-given-experimental- drugs
B) Choosing-appropriate-patients-to-be-involved-in-the-drug- study
C) Monitoring-and-observing-patients-closely-for-adverse- effects
D) Conducting-research-to-determine-effectiveness-of-the- drug
Ans: C
Feedback:
Phase-III-studies-involve-use-of-a-drug-in-a-vast-clinical-population-in-which-
patients-are-asked-to-record-any-symptoms-they-experience-while-taking-the-
drugs.-Nurses-may-be-responsible-for-helping-collect-and-analyze-the-
information-to-be-shared-with-the-Food-and-Drug-Administration-(FDA)-but-
would-not-conduct-research-independently-because-nurses-do-not-prescribe-
medications.-Use-of-animals-in-drug-testing-is-done-in-the-preclinical-trials.-
Select-patients-who-are-involved-in-phase-II-studies-to-participate-in-studies-
where-the-participants-have-the-disease-the-drug-is-intended-to-treat.-These-
patients-are-monitored-closely-for-drug-action-and-adverse-effects.-Phase-I-
studies-involve-healthy-human-volunteers-who-are-usually-paid-for-their-
participation.-Nurses-may-observe-for-adverse-effects-and-toxicity.
4. What-concept-is-considered-when-generic-drugs-are-substituted-for-brand-
name-drugs?
A) Bioavailability
