Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
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Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
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Chapterb1.bIntroduction:bThebNaturebofbDrugsb&bDrugbDevelopmentb&bRegulation
1.
Abnursebworkingbinbradiologybadministersbiodinebtobabpatientbwhobisbhavingb
abcomputedbtomographyb(CT)bscan.bThebnursebworkingbonbtheboncologybunitba
dministersbchemotherapybtobpatientsbwhobhavebcancer.bAtbthebPublicbHealthbD
epartment,babnursebadministersbabmeasles-mumps-
rubellab(MMR)bvaccinebtobab14-month-
oldbchildbasbabroutinebimmunization.bWhichbbranchbofbpharmacologybbestbdesc
ribesbthebactionsbofballbthreeb nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacologybisbthebstudybofbthebbiologicbeffectsbofbchemicals.bNursesbarebinv
olvedbwithbclinicalbpharmacologyborbpharmacotherapeutics,bwhichbisbabbranchb
ofbpharmacologybthatbdealsbwithbthebusesbofbdrugsbtobtreat,bprevent,bandbdiagno
sebdisease.bThebradiologybnursebisbadministeringbabdrugbtobhelpbdiagnosebabdise
ase.bTheboncologybnursebisbadministeringbabdrugbtobhelpbtreatbabdisease.bPharma
coeconomicsbincludesbanybcostsbinvolvedbinbdrugb therapy.
Pharmacodynamicsbinvolvesbhowbabdrugbaffectsbthebbodybandb
pharmacokineticsbisbhowbthebbodybactsbonbthebbody.
2.
Abphysicianbhasborderedbintramuscularb(IM)binjectionsbofbmorphine,babnarc
otic,beveryb4bhoursbasbneededbforbpainbinbabmotorbvehiclebaccidentbvictim.bTheb
nursebisbawarebthisbdrugbhasbabhighbabusebpotential.bUnderbwhatbcategorybwoul
dbmorphinebbebclassified?
A) SchedulebI
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B) SchedulebII
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C) SchedulebIII
D) SchedulebIV
Ans: B
Feedback:
NarcoticsbwithbabhighbabusebpotentialbarebclassifiedbasbSchedulebIIbdrugsbbeca
usebofbseverebdependencebliability.bSchedulebIbdrugsbhavebhighbabusebpotentia
lbandbnobacceptedbmedicalbuse.bSchedulebIIIbdrugsbhavebablesserbabusebpotenti
albthanbIIbandbanbacceptedbmedicalbuse.bSchedulebIVbdrugsbhaveblowbabusebpot
entialbandblimitedbdependenceb liability.
3.
WhenbinvolvedbinbphasebIIIbdrugbevaluationbstudies,bwhatbresponsibiliti
esbwouldbthebnursebhave?
A) Workingbwithbanimalsbwhobarebgivenbexperimentalb drugs
B) Choosingbappropriatebpatientsbtobbebinvolvedbinbthebdrugb study
C) Monitoringbandbobservingbpatientsbcloselybforbadverseb effects
D) Conductingbresearchbtobdeterminebeffectivenessbofbtheb drug
Ans: C
Feedback:
PhasebIIIbstudiesbinvolvebusebofbabdrugbinbabvastbclinicalbpopulationbinbwhichbp
atientsbarebaskedbtobrecordbanybsymptomsbtheybexperiencebwhilebtakingbthebdr
ugs.bNursesbmaybbebresponsiblebforbhelpingbcollectbandbanalyzebthebinformati
onbtobbebsharedbwithbthebFoodbandbDrugbAdministrationb(FDA)bbutbwouldbnotb
conductbresearchbindependentlybbecausebnursesbdobnotbprescribebmedications
.bUsebofbanimalsbinbdrugbtestingbisbdonebinbthebpreclinicalbtrials.bSelectbpatient
sbwhobarebinvolvedbinbphasebIIbstudiesbtobparticipatebinbstudiesbwherebthebpart
icipantsbhavebthebdiseasebthebdrugbisbintendedbtobtreat.bThesebpatientsbarebmon
itoredbcloselybforbdrugbactionbandbadversebeffects.bPhasebIbstudiesbinvolvebhe
althybhumanbvolunteersbwhobarebusuallybpaidbforbtheirbparticipation.bNursesb
maybobservebforbadversebeffectsbandbtoxicity.
4.
Whatbconceptbisbconsideredbwhenbgenericbdrugsbarebsubstitutedbforbbra
ndbnamebdrugs?
A) Bioavailability
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B) Criticalbconcentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailabilitybisbthebportionbofbabdosebofbabdrugbthatbreachesbthebsystemicbcir
culationbandbisbavailablebtobactbonbbodybcells.bBindersbusedbinbabgenericbdrugb
maybnotbbebthebsamebasbthosebusedbinbthebbrandbnamebdrug.bTherefore,bthebwa
ybthebbodybbreaksbdownbandbusesbthebdrugbmaybdiffer,bwhichbmaybeliminatebab
genericbdrugbsubstitution.bCriticalbconcentrationbisbthebamountbofbabdrugbthatbi
sbneededbtobcausebabtherapeuticbeffectbandbshouldbnotbdifferbbetweenbgenericba
ndbbrandbnamebmedications.bDistributionbisbthebphasebofbpharmacokinetics,bw
hichbinvolvesbthebmovementbofbabdrugbtobthebbodysbtissuesbandbisbthebsamebinb
genericbandbbrandbnamebdrugs.bAbdrugsbhalf-
lifebisbthebtimebitbtakesbforbthebamountbofbdrugbtobdecreasebtobhalfbthebpeakbleve
l,bwhichbshouldbnotbchangebwhenbsubstitutingbabgenericb medication.
5.
Abnursebisbassessingbthebpatientsbhomebmedicationbuse.bAfterblisteningbtobt
hebpatientblistbcurrentbmedications,bthebnursebasksbwhatbpriorityb question?
A) Dobyoubtakebanybgenericb medications?
B) Arebanybofbthesebmedicationsborphanb drugs?
C) Arebthesebmedicationsbsafebtobtakebduringb pregnancy?
D) Dobyoubtakebanybover-the-counterb medications?
Ans: D
Feedback:
Itbisbimportantbforbthebnursebtobspecificallybquestionbusebofbover-the-
counterbmedicationsbbecausebpatientsbmaybnotbconsiderbthembimportant.bTheb
patientbisbunlikelybtobknowbthebmeaningbofborphanbdrugsbunlessbtheybtoobarebh
ealthbcarebproviders.bSafetybduringbpregnancy,busebofbabgenericbmedication,bo
rbclassificationbofborphanbdrugsbarebthingsbthebpatientbwouldbbebunablebtobans
werbbutbcouldbbebfoundbinbreferencebbooksbifbthebnursebwishesbtobresearchbthe
m.
WWW.THENURSINGMASTERY.COM
WWW.NURSYLAB.COM
b b b b b b b b b
FULL TESTBANK
b
INSTANT DOWNLOAD!!
b
TEST BANK b
, Pageb1bofb822
Basic and Clinical Pharmacology 14th Edition Katzung Trevor Test Bank
b b b b b b b b b
Chapterb1.bIntroduction:bThebNaturebofbDrugsb&bDrugbDevelopmentb&bRegulation
1.
Abnursebworkingbinbradiologybadministersbiodinebtobabpatientbwhobisbhavingb
abcomputedbtomographyb(CT)bscan.bThebnursebworkingbonbtheboncologybunitba
dministersbchemotherapybtobpatientsbwhobhavebcancer.bAtbthebPublicbHealthbD
epartment,babnursebadministersbabmeasles-mumps-
rubellab(MMR)bvaccinebtobab14-month-
oldbchildbasbabroutinebimmunization.bWhichbbranchbofbpharmacologybbestbdesc
ribesbthebactionsbofballbthreeb nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacologybisbthebstudybofbthebbiologicbeffectsbofbchemicals.bNursesbarebinv
olvedbwithbclinicalbpharmacologyborbpharmacotherapeutics,bwhichbisbabbranchb
ofbpharmacologybthatbdealsbwithbthebusesbofbdrugsbtobtreat,bprevent,bandbdiagno
sebdisease.bThebradiologybnursebisbadministeringbabdrugbtobhelpbdiagnosebabdise
ase.bTheboncologybnursebisbadministeringbabdrugbtobhelpbtreatbabdisease.bPharma
coeconomicsbincludesbanybcostsbinvolvedbinbdrugb therapy.
Pharmacodynamicsbinvolvesbhowbabdrugbaffectsbthebbodybandb
pharmacokineticsbisbhowbthebbodybactsbonbthebbody.
2.
Abphysicianbhasborderedbintramuscularb(IM)binjectionsbofbmorphine,babnarc
otic,beveryb4bhoursbasbneededbforbpainbinbabmotorbvehiclebaccidentbvictim.bTheb
nursebisbawarebthisbdrugbhasbabhighbabusebpotential.bUnderbwhatbcategorybwoul
dbmorphinebbebclassified?
A) SchedulebI
WWW.THENURSINGMASTERY.COM
WWW.NURSYLAB.COM
, Pageb2bofb822
B) SchedulebII
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, Pageb3bofb822
C) SchedulebIII
D) SchedulebIV
Ans: B
Feedback:
NarcoticsbwithbabhighbabusebpotentialbarebclassifiedbasbSchedulebIIbdrugsbbeca
usebofbseverebdependencebliability.bSchedulebIbdrugsbhavebhighbabusebpotentia
lbandbnobacceptedbmedicalbuse.bSchedulebIIIbdrugsbhavebablesserbabusebpotenti
albthanbIIbandbanbacceptedbmedicalbuse.bSchedulebIVbdrugsbhaveblowbabusebpot
entialbandblimitedbdependenceb liability.
3.
WhenbinvolvedbinbphasebIIIbdrugbevaluationbstudies,bwhatbresponsibiliti
esbwouldbthebnursebhave?
A) Workingbwithbanimalsbwhobarebgivenbexperimentalb drugs
B) Choosingbappropriatebpatientsbtobbebinvolvedbinbthebdrugb study
C) Monitoringbandbobservingbpatientsbcloselybforbadverseb effects
D) Conductingbresearchbtobdeterminebeffectivenessbofbtheb drug
Ans: C
Feedback:
PhasebIIIbstudiesbinvolvebusebofbabdrugbinbabvastbclinicalbpopulationbinbwhichbp
atientsbarebaskedbtobrecordbanybsymptomsbtheybexperiencebwhilebtakingbthebdr
ugs.bNursesbmaybbebresponsiblebforbhelpingbcollectbandbanalyzebthebinformati
onbtobbebsharedbwithbthebFoodbandbDrugbAdministrationb(FDA)bbutbwouldbnotb
conductbresearchbindependentlybbecausebnursesbdobnotbprescribebmedications
.bUsebofbanimalsbinbdrugbtestingbisbdonebinbthebpreclinicalbtrials.bSelectbpatient
sbwhobarebinvolvedbinbphasebIIbstudiesbtobparticipatebinbstudiesbwherebthebpart
icipantsbhavebthebdiseasebthebdrugbisbintendedbtobtreat.bThesebpatientsbarebmon
itoredbcloselybforbdrugbactionbandbadversebeffects.bPhasebIbstudiesbinvolvebhe
althybhumanbvolunteersbwhobarebusuallybpaidbforbtheirbparticipation.bNursesb
maybobservebforbadversebeffectsbandbtoxicity.
4.
Whatbconceptbisbconsideredbwhenbgenericbdrugsbarebsubstitutedbforbbra
ndbnamebdrugs?
A) Bioavailability
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, Pageb4bofb822
B) Criticalbconcentration
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailabilitybisbthebportionbofbabdosebofbabdrugbthatbreachesbthebsystemicbcir
culationbandbisbavailablebtobactbonbbodybcells.bBindersbusedbinbabgenericbdrugb
maybnotbbebthebsamebasbthosebusedbinbthebbrandbnamebdrug.bTherefore,bthebwa
ybthebbodybbreaksbdownbandbusesbthebdrugbmaybdiffer,bwhichbmaybeliminatebab
genericbdrugbsubstitution.bCriticalbconcentrationbisbthebamountbofbabdrugbthatbi
sbneededbtobcausebabtherapeuticbeffectbandbshouldbnotbdifferbbetweenbgenericba
ndbbrandbnamebmedications.bDistributionbisbthebphasebofbpharmacokinetics,bw
hichbinvolvesbthebmovementbofbabdrugbtobthebbodysbtissuesbandbisbthebsamebinb
genericbandbbrandbnamebdrugs.bAbdrugsbhalf-
lifebisbthebtimebitbtakesbforbthebamountbofbdrugbtobdecreasebtobhalfbthebpeakbleve
l,bwhichbshouldbnotbchangebwhenbsubstitutingbabgenericb medication.
5.
Abnursebisbassessingbthebpatientsbhomebmedicationbuse.bAfterblisteningbtobt
hebpatientblistbcurrentbmedications,bthebnursebasksbwhatbpriorityb question?
A) Dobyoubtakebanybgenericb medications?
B) Arebanybofbthesebmedicationsborphanb drugs?
C) Arebthesebmedicationsbsafebtobtakebduringb pregnancy?
D) Dobyoubtakebanybover-the-counterb medications?
Ans: D
Feedback:
Itbisbimportantbforbthebnursebtobspecificallybquestionbusebofbover-the-
counterbmedicationsbbecausebpatientsbmaybnotbconsiderbthembimportant.bTheb
patientbisbunlikelybtobknowbthebmeaningbofborphanbdrugsbunlessbtheybtoobarebh
ealthbcarebproviders.bSafetybduringbpregnancy,busebofbabgenericbmedication,bo
rbclassificationbofborphanbdrugsbarebthingsbthebpatientbwouldbbebunablebtobans
werbbutbcouldbbebfoundbinbreferencebbooksbifbthebnursebwishesbtobresearchbthe
m.
WWW.THENURSINGMASTERY.COM
WWW.NURSYLAB.COM
