Top 100 MOA--full list 2023|2023 LATEST UPDATE|GUARANTEED SUCCESS

Abilify Aripiprazole Partial agonist at D2 and 5HT1A receptors Antagonist at 5HT2A receptors Activase alteplase -thrombolytic agent -recombinant form of human tissue pasminogen activator -helps to convert plasminogen to plasmin. Plasmin degrades fibrin and fibrinogen 00:03 01:18 Adderall (XR) Amphetamine and Dextroamphetamine Salts -promote the release and inhibit the reuptake of DA and NE -Non-catecholamine sympathomimetic agent that stimulate the release of NE and other biologic amines from central adrenergic receptors Advair Fluticasone and Salmeterol Combination of anti-inflammatory corticosteroid and long acting, non-selective beta-agonist Advil/Motrin/Caldolor Ibuprofen -blocks prostaglandin synthesis by inhibiting COX-1 and COX-2 Aldactone Spironolactone -Potassium sparing diuretic -compete with aldosterone for receptor sites in distal tubule Alphagan (P) Brimonidine Selective alpha-2 agonist -decreases aqueous humor production and increases outflow Altace Ramipril ACE inhibitor Amaryl Glimepiride -Increases insulin secretion by stimulating pancreatic islet cells -sulfonylurea -acts on pancreas Ambien (CR)/Zolpmist/Edluar Zolpidem Non-BZD sedation hypnotic Short half life and no active metabolites Amitiza Lubiprostone -PGE1 derivative -Increases intestinal fluid secretion by chloride channel activation Aranesp Darbepoetin alfa Stimulates erythropoiesis (recombinant form) 00:01 01:18 Argatroban Direct, highly selective thrombin inhibitor Aricept Donepezil Inhibits ACh-esterase to improve the availability of ACh Arixtra Fondaparinux Indirect factor Xa inhibitor Asacol/Apriso/Lialda Mesalamine -mechanism not well known -block production of prostaglandins and leukotrienes -inhibition of bacterial induced chemotaxis -scavenge reactive oxygen -prodrug to 5-ASA Aspirin Irreversible inhibition of COX-1/2 - decreased TXA2 (stopping platelet aggregation) Ativan Lorazepam Enhances inhibitor effect of GABA by increasing neuronal membrane permeability to chloride ions Augmentin (XR) Amoxicillin and Clavulanate Beta-lactam antibiotic with beta-lactamase inhibitor Avelox Moxifloxacin DNA gyrase (topoisomerase II) & topoisomerase IV inhibitor Bactrim (DS)/Septra (DS) Sulfamethoxazole / Trimethoprim SMX interferes with bacteria folic acid synthesis TMP inhibtors dihydrofolic acid reduction (enzymes) Bactroban Mupirocin Binds to bacterial isoleucyl tRNA synthase --> inhibition of protein synthesis Benadryl diphenhydramine -antihistamine -competitively antagonizes the effects of histamine on H1 receptors in GI tract, uterus, large blood vessels, and bronchial muscle -possesses anticholinergic properties Brilinta ticagrelor -antiplatelet -reversibly binds to platelet receptor preventing platelet activation BuSpar Buspirone UNKNOWN MOA High affinity for 5HT1A &2 receptors w/o affecting BZD/GABA receptors Byetta Exenatide Analog of incretin Increases insulin secretion Increases B cell replication Slows gastric emptying May decrease food intake Cardizem/Cartia/Dilacor/Tiazac Diltiazem Prevents Ca from entering "slow channels" during depolarization of the myocardium Relaxes coronary smooth muscle Increases myocardial oxygen delivery Cardura (XL) Doxazosin -inhibit adrenergic stimulation of peripheral alpha1-receptors -> reduced peripheral resistance and vasodilation Catapres Clonidine -agonist at presynaptic alpha2-receptors in the medulla. Stimulation results in inhibition of sympathetic outflow and tone. Lowers PVR Celebrex Celecoxib Inhibits COX2 selectively and thus inhibiting prostaglandin synthesis