CMN 577 - Unit 1| 150 QUESTIONS| WITH COMPLETE SOLUTIONS

S/S of acute intermittent porphyria Correct Answer: + Abdominal pain of varying severity + Absence of fever or leukocytosis + Peripheral neuropathy (symmetric OR asymmetric) + CNS sx (seizures, altered consciousness, psuychosis, abnormalities of basal ganglia) + Hyponatremia McPhee p 1690 Labs for acute intermittent porphyria Correct Answer: + Hyponatremia + Urine which turns dark when exposed to light or air (r/t porphobilonogen excretion) McPhee p 1690 Prevention of attacks in pts with acute intermittent porphyria Correct Answer: + Sulfanoamides and barbituates + Starvation or prolonged fasting + Hormone changes during pregnancy McPhee p 1690 Typical patient with AIP Correct Answer: Young female McPhee p 1690 Treatment for acute intermittent porphyria (AIP) Correct Answer: + High carb diet + Analgesics and IV glucose in saline and hematin McPhee p 1691 Cause of acute intermittent porphyria (AIP) Correct Answer: Genetic condition, inherited as an autosomal dominant condition. Pts have mutation in HMBS McPHee p 1690 At what point in pregnancy can Down Syndrome be detected, and what tests are used? Correct Answer: + Down syndrome can be detected in the 1st or early 2nd trimester + Screen maternal serum for alpha-fetoprotein (should be LOW) and other biomarkers (multiple marker screening) + Detecting nuchal thicknes