Page | 1
CMN 548 FINAL EXAM WITH 100% VERIFIED
QUESTIONS AND CORRECT ANSWERS LATEST
UPDATE 2026/2027 | PASS A+.
what medications are irreversible MAOIs (MAOA&B and MAOB
MAOB)? - correct answer -Isocarboxazid (Marplan), Phenelzine
(Nardil), Tranylcypromine (Parnate), Selegiline Transdermal (Emasam)
What are the most frequent adverse effects of irreversible MAOIs? -
correct answer -MAOA&B: dizziness, drowsiness, fatigue, headache
(without increased BP), hyperreflexia, & sleep disturbances
Reversible MAOIs (RIMAs) Include what medication? - correct answer
-Maclobemide (Manerix)
How long will it take to recover MAO activity after a final dose of
RIMA? - correct answer -24-48 hours
What are the most frequent adverse effects of RIMAs? - correct answer
-orthostatic hypotension, insomnia, weight gain, edema & sexual
dysfunction, insomnia tx by dividing doses, not giving after dinner, and
using trazodone
, Page | 2
A single dose of irreversible MAOIs may persist in its inhibition of
MAO for how long? - correct answer -2 weeks
Irreversible MAOA&B used to treat: - correct answer -Depression,
atypical
MDD, unresponsive to other antidepressants
Irreversible MAO-B used to treat: - correct answer -MDD in adults
What is the treatment for MAOI induced orthostatic hypotension?
- correct answer -•Avoidance of caffeine, intake of 2L of fluid/day,
addition of dietary salt, adjustment of HTN meds, support stockings
•fludrocortisone 0.1-0.2mg/day for severe cases
•Advise pts to get out of bed slowly
How long should the PNP wait to begin an MAOI after discontinuing a
patient from fluoxetine (Prozac)? - correct answer -Don't
use within 5 weeks of prozac
Describe potential complications for using MAOIs for patients who have
Bipolar I and Schizophrenia. - correct answer -Induction of mania in
, Page | 3
persons in the depressed phase of BPI & triggering psychotic
decompensating in persons w/ schizophrenia
MAOIs are used to treat what conditions? - correct answer Depression,
bipolar depression, panic disorder, social phobia, bulimia, PTSD, angina
pain, atypical face pain, migraine, ADHD, idiopathic orthostatic HTN,
& depression r/t brain injury
Reversible MAO-A (RIMA) used to treat: - correct answer -MDD,
dysthymic, chronic
What are the symptoms of a tyramine-induced hypertensive crisis? -
correct answer -Results from inactive GI metabolism of dietary
Tyramine due to the MAOI's
Sxs: HA usually 1st sx, severe HTN, stiff neck, diaphoresis, nausea,
vomiting
Management: a-adrenergic antagonists such as phentolamine (regitine)
or chlorpromazine (thorazine) they will lower BP w/in 5 minutes. IV
furosemide (Lasix) to reduce fluid load, and Badrenergic receptor
agonists for tachycardia. SL nifedipine (Procardia) can be given.
, Page | 4
Tyramine containing foods should be avoided for how long after
discontinuing an irreversible MAOI? - correct answer -2 weeks
How long should the Psychiatric Nurse Practitioner wait to begin
another treatment for depression when stopping an MAOI to begin
either another MAOI or an SSRI? - correct answer -When changing
from one MAOI to another taper and stop use of the first drug for 10-14
days before beginning the second drug
What are the indications for use for TCAs? - correct answer - MDD,
panic disorder, GAD, OCD, PTSD, & pain syndromes
Why are TCAs not recommended to use in patients with Bipolar I and
Bipolar II? - correct answer -May induce manic episodes in up to 50%
of bipolar patients; risk of cycling more likely to induce mania,
hypomania, or cycling than new antidepressants
Why is it important to titrate TCAs slowly in patients with panic or
anxiety disorders? - correct answer -Because of the potential initial
anxiogenic effects of TCA's
CMN 548 FINAL EXAM WITH 100% VERIFIED
QUESTIONS AND CORRECT ANSWERS LATEST
UPDATE 2026/2027 | PASS A+.
what medications are irreversible MAOIs (MAOA&B and MAOB
MAOB)? - correct answer -Isocarboxazid (Marplan), Phenelzine
(Nardil), Tranylcypromine (Parnate), Selegiline Transdermal (Emasam)
What are the most frequent adverse effects of irreversible MAOIs? -
correct answer -MAOA&B: dizziness, drowsiness, fatigue, headache
(without increased BP), hyperreflexia, & sleep disturbances
Reversible MAOIs (RIMAs) Include what medication? - correct answer
-Maclobemide (Manerix)
How long will it take to recover MAO activity after a final dose of
RIMA? - correct answer -24-48 hours
What are the most frequent adverse effects of RIMAs? - correct answer
-orthostatic hypotension, insomnia, weight gain, edema & sexual
dysfunction, insomnia tx by dividing doses, not giving after dinner, and
using trazodone
, Page | 2
A single dose of irreversible MAOIs may persist in its inhibition of
MAO for how long? - correct answer -2 weeks
Irreversible MAOA&B used to treat: - correct answer -Depression,
atypical
MDD, unresponsive to other antidepressants
Irreversible MAO-B used to treat: - correct answer -MDD in adults
What is the treatment for MAOI induced orthostatic hypotension?
- correct answer -•Avoidance of caffeine, intake of 2L of fluid/day,
addition of dietary salt, adjustment of HTN meds, support stockings
•fludrocortisone 0.1-0.2mg/day for severe cases
•Advise pts to get out of bed slowly
How long should the PNP wait to begin an MAOI after discontinuing a
patient from fluoxetine (Prozac)? - correct answer -Don't
use within 5 weeks of prozac
Describe potential complications for using MAOIs for patients who have
Bipolar I and Schizophrenia. - correct answer -Induction of mania in
, Page | 3
persons in the depressed phase of BPI & triggering psychotic
decompensating in persons w/ schizophrenia
MAOIs are used to treat what conditions? - correct answer Depression,
bipolar depression, panic disorder, social phobia, bulimia, PTSD, angina
pain, atypical face pain, migraine, ADHD, idiopathic orthostatic HTN,
& depression r/t brain injury
Reversible MAO-A (RIMA) used to treat: - correct answer -MDD,
dysthymic, chronic
What are the symptoms of a tyramine-induced hypertensive crisis? -
correct answer -Results from inactive GI metabolism of dietary
Tyramine due to the MAOI's
Sxs: HA usually 1st sx, severe HTN, stiff neck, diaphoresis, nausea,
vomiting
Management: a-adrenergic antagonists such as phentolamine (regitine)
or chlorpromazine (thorazine) they will lower BP w/in 5 minutes. IV
furosemide (Lasix) to reduce fluid load, and Badrenergic receptor
agonists for tachycardia. SL nifedipine (Procardia) can be given.
, Page | 4
Tyramine containing foods should be avoided for how long after
discontinuing an irreversible MAOI? - correct answer -2 weeks
How long should the Psychiatric Nurse Practitioner wait to begin
another treatment for depression when stopping an MAOI to begin
either another MAOI or an SSRI? - correct answer -When changing
from one MAOI to another taper and stop use of the first drug for 10-14
days before beginning the second drug
What are the indications for use for TCAs? - correct answer - MDD,
panic disorder, GAD, OCD, PTSD, & pain syndromes
Why are TCAs not recommended to use in patients with Bipolar I and
Bipolar II? - correct answer -May induce manic episodes in up to 50%
of bipolar patients; risk of cycling more likely to induce mania,
hypomania, or cycling than new antidepressants
Why is it important to titrate TCAs slowly in patients with panic or
anxiety disorders? - correct answer -Because of the potential initial
anxiogenic effects of TCA's
