Explain metastasis and how it occurs:
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A cancer cell must break loose from the primary tumor, invade the
surrounding extracellular matrix, gain access to a blood vessel, survive its
passage in the bloodstream, emerge at a favorable location, invade the
surrounding tissue, begin to grow, and establish a blood supply.
What the 6 molecular and cellular mechanisms that are known to facilitate the
development of cancer?
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, Defects in DNA repair mechanisms, defects in growth factor signaling
pathways, evasion of apoptosis, avoidance of cellular senescence,
development of sustained angiogenesis, and metastasis and invasion.
Malignant
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Cell characteristics: undifferentiated cells, atypical structure that don’t look
like cells in tissue of origin
Rate of growth: variable; greater undifferentiated, more rapid the rate of
growth
Mode of growth: grows by invasion, infiltrating the surrounding tissues
Metastasis: gains access to blood lymph channels to metastasize to other
areas of body
When would surgery be appropriate in the treatment of cancer?
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1. If the tumor is small with well-defines margins. It can be used to treat
oncologic emergencies and be used as prophylactic measures.
2. neutropenia, anemia, thrombocytopenia
neoplasia and neoplasm:
Give this one a try later!
A cancer cell must break loose from the primary tumor, invade the
surrounding extracellular matrix, gain access to a blood vessel, survive its
passage in the bloodstream, emerge at a favorable location, invade the
surrounding tissue, begin to grow, and establish a blood supply.
What the 6 molecular and cellular mechanisms that are known to facilitate the
development of cancer?
Give this one a try later!
, Defects in DNA repair mechanisms, defects in growth factor signaling
pathways, evasion of apoptosis, avoidance of cellular senescence,
development of sustained angiogenesis, and metastasis and invasion.
Malignant
Give this one a try later!
Cell characteristics: undifferentiated cells, atypical structure that don’t look
like cells in tissue of origin
Rate of growth: variable; greater undifferentiated, more rapid the rate of
growth
Mode of growth: grows by invasion, infiltrating the surrounding tissues
Metastasis: gains access to blood lymph channels to metastasize to other
areas of body
When would surgery be appropriate in the treatment of cancer?
Give this one a try later!
1. If the tumor is small with well-defines margins. It can be used to treat
oncologic emergencies and be used as prophylactic measures.
2. neutropenia, anemia, thrombocytopenia
neoplasia and neoplasm:
