Lehninger-Principles-of-Biochemistry-8th-edition-Chapter-1-Question-
and-Answers
1. The-birth-of-modern-biochemistry-can-be-traced-to-the---CORRECT-ANSWER-
end-of-the-19th-century
2. The-study-of-biochemistry-attempts-to-explain---CORRECT-ANSWER-biological-
processes-at-the-molecular-and-cellular-level.
3. Enzymes-function-as-reaction-catalysts-in-cells.-If-the-enzymes-were-removed-
from-a-cell,-the-rate-of-biochemical-reactions-would---CORRECT-ANSWER-
decrease
4. The-essential-ions-calcium,-magnesium,-potassium,-and-sodium-are-all---
CORRECT-ANSWER-cations
5. Given-that-methane-(CH4)-has-a-bond-angle-of-109.5°-and-ethylene-(C2H2)-has-a-
bond-angle-of-120°,-what-is-the-correct-bond-angle-for-acetylene-(C2H2)?---
CORRECT-ANSWER-180°
6. Amino-acids-are-the-building-blocks-for-which-biomolecule(s)?---CORRECT-
ANSWER-proteins
7. The-__________-differentiates-amino-acids-from-one-another.---CORRECT-
ANSWER-side-chains-attached-to-the-central-carbon
8. A-nucleotide-consists-of---CORRECT-ANSWER-nitrogenous-base,-five-membered-
sugar-and-phosphate-groups
9. Simple-sugars-are-made-of---CORRECT-ANSWER-carbon,-oxygen,-and-hydrogen
10. If-energy-in-the-form-of-ATP-is-required-to-make-a-polymeric-macromolecule,-
what-will-happen-if-there-is-no-ATP-available?---CORRECT-ANSWER-The-
polymer-is-broken-down-to-release-ATP.
11. Why-are-fewer-polypeptide-sequences-encountered-biologically-than-are-
theoretically-possible?---CORRECT-ANSWER-Not-all-have-useful-structural-and-
functional-properties.
12. Humans-do-not-have-the-enzyme-cellulase.-Is-it-likely-that-a-human-could-
survive-on-a-plant-only-diet?---CORRECT-ANSWER-No,-not-enough-ATP-would-
be-produced-to-generate-energy.
, Lehninger-Principles-of-Biochemistry-8th-edition-Chapter-1-Question-
and-Answers
13. Which-two-functional-groups-are-involved-in-producing-a-peptide-bond?---
CORRECT-ANSWER-amino-and-carboxyl
14. Even-though-amylose-and-cellulose-contain-the-same-repeating-unit-of-glucose,-
they-are-very-different-in-terms-of-function.-Why?---CORRECT-ANSWER-The-
orientations-of-the-glycosidic-bond-are-different
15. The-correct-definition-of-a-pathway-intermediate-is-a-molecule-that---CORRECT-
ANSWER-is-both-a-product-and-a-reactant-in-a-pathway.
16. Plasmids-are-small,-circular-DNA-molecules-that-are-used-in-which-of-the-
following?
a. gene-cloning
b. production-of-chromatin
c. cell-movement
d. replication-of-nucleus---CORRECT-ANSWER-gene-cloning
17. What-is-the-function-of-the-chloroplast-in-a-plant-cell?---CORRECT-ANSWER-
conversion-of-light-energy-to-chemical-energy
18. If-a-plasma-membrane-is-hydrophobic,-what-kinds-of-amino-acids-are-MOST-
likely-to-be-found-in-the-membrane?---CORRECT-ANSWER-hydrophobic-amino-
acids
19. When-a-ligand-binds-to-a-receptor,-it-causes-the-receptor-to---CORRECT-
ANSWER-activate
20. How-does-the-molecule-adenosine-monophosphate-fit-into-the-seven-hierarchical-
levels-that-define-the-chemical-basis-of-life?---CORRECT-ANSWER-biomolecule
21. The-main-difference-between-deoxyribonucleotides-and-ribonucleotides-is-that-
they-have-a-different---CORRECT-ANSWER-functional-group-on-the-2′-carbon.
22. A-hydrogen-bond-can-best-be-described-as-a---CORRECT-ANSWER-weak-
noncovalent-interaction.
23. Why-can-a-guanine-not-be-paired-with-adenine?---CORRECT-ANSWER-Guanine-
can-form-three-hydrogen-bonds-and-adenine-can-form-two.
24. What-structural-feature-of-DNA-is-attributed-to-the-fact-that-the-two-DNA-
strands-areantiparallel?---CORRECT-ANSWER-DNA-is-a-right-handed-helix.
and-Answers
1. The-birth-of-modern-biochemistry-can-be-traced-to-the---CORRECT-ANSWER-
end-of-the-19th-century
2. The-study-of-biochemistry-attempts-to-explain---CORRECT-ANSWER-biological-
processes-at-the-molecular-and-cellular-level.
3. Enzymes-function-as-reaction-catalysts-in-cells.-If-the-enzymes-were-removed-
from-a-cell,-the-rate-of-biochemical-reactions-would---CORRECT-ANSWER-
decrease
4. The-essential-ions-calcium,-magnesium,-potassium,-and-sodium-are-all---
CORRECT-ANSWER-cations
5. Given-that-methane-(CH4)-has-a-bond-angle-of-109.5°-and-ethylene-(C2H2)-has-a-
bond-angle-of-120°,-what-is-the-correct-bond-angle-for-acetylene-(C2H2)?---
CORRECT-ANSWER-180°
6. Amino-acids-are-the-building-blocks-for-which-biomolecule(s)?---CORRECT-
ANSWER-proteins
7. The-__________-differentiates-amino-acids-from-one-another.---CORRECT-
ANSWER-side-chains-attached-to-the-central-carbon
8. A-nucleotide-consists-of---CORRECT-ANSWER-nitrogenous-base,-five-membered-
sugar-and-phosphate-groups
9. Simple-sugars-are-made-of---CORRECT-ANSWER-carbon,-oxygen,-and-hydrogen
10. If-energy-in-the-form-of-ATP-is-required-to-make-a-polymeric-macromolecule,-
what-will-happen-if-there-is-no-ATP-available?---CORRECT-ANSWER-The-
polymer-is-broken-down-to-release-ATP.
11. Why-are-fewer-polypeptide-sequences-encountered-biologically-than-are-
theoretically-possible?---CORRECT-ANSWER-Not-all-have-useful-structural-and-
functional-properties.
12. Humans-do-not-have-the-enzyme-cellulase.-Is-it-likely-that-a-human-could-
survive-on-a-plant-only-diet?---CORRECT-ANSWER-No,-not-enough-ATP-would-
be-produced-to-generate-energy.
, Lehninger-Principles-of-Biochemistry-8th-edition-Chapter-1-Question-
and-Answers
13. Which-two-functional-groups-are-involved-in-producing-a-peptide-bond?---
CORRECT-ANSWER-amino-and-carboxyl
14. Even-though-amylose-and-cellulose-contain-the-same-repeating-unit-of-glucose,-
they-are-very-different-in-terms-of-function.-Why?---CORRECT-ANSWER-The-
orientations-of-the-glycosidic-bond-are-different
15. The-correct-definition-of-a-pathway-intermediate-is-a-molecule-that---CORRECT-
ANSWER-is-both-a-product-and-a-reactant-in-a-pathway.
16. Plasmids-are-small,-circular-DNA-molecules-that-are-used-in-which-of-the-
following?
a. gene-cloning
b. production-of-chromatin
c. cell-movement
d. replication-of-nucleus---CORRECT-ANSWER-gene-cloning
17. What-is-the-function-of-the-chloroplast-in-a-plant-cell?---CORRECT-ANSWER-
conversion-of-light-energy-to-chemical-energy
18. If-a-plasma-membrane-is-hydrophobic,-what-kinds-of-amino-acids-are-MOST-
likely-to-be-found-in-the-membrane?---CORRECT-ANSWER-hydrophobic-amino-
acids
19. When-a-ligand-binds-to-a-receptor,-it-causes-the-receptor-to---CORRECT-
ANSWER-activate
20. How-does-the-molecule-adenosine-monophosphate-fit-into-the-seven-hierarchical-
levels-that-define-the-chemical-basis-of-life?---CORRECT-ANSWER-biomolecule
21. The-main-difference-between-deoxyribonucleotides-and-ribonucleotides-is-that-
they-have-a-different---CORRECT-ANSWER-functional-group-on-the-2′-carbon.
22. A-hydrogen-bond-can-best-be-described-as-a---CORRECT-ANSWER-weak-
noncovalent-interaction.
23. Why-can-a-guanine-not-be-paired-with-adenine?---CORRECT-ANSWER-Guanine-
can-form-three-hydrogen-bonds-and-adenine-can-form-two.
24. What-structural-feature-of-DNA-is-attributed-to-the-fact-that-the-two-DNA-
strands-areantiparallel?---CORRECT-ANSWER-DNA-is-a-right-handed-helix.
