Louise101

12 Page summary of main topics in cell signalling. Contents: Wnt signalling 1 Canonical (Wnt/Catenin) and Non-canonical (Wnt/Planar Cell Polarity and Wnt/Ca2+ Signalling) pathways 1 GRB2 and the activation of the MAP Kinase cascade 2 Insulin receptor 2 The regulation of cell polarity 3 The molecular basis of vision in the rod cells and Rhodopsin-mediated signalling. 4 JAK-STAT Signalling 5 Insulin Receptor 6 Transforming growth factor-β (TGFβ) 7 The Estrogen Receptor 8 GPCR’s ...

A+ essay. MICR20050 The main ways by which microorganisms and microbial communities have been manipulated for the benefit of mankind Sample Essay. Topics include probiotics, bioremediation, CRISPR, microbiome, antibiotics. Fully referenced and bibliography and diagrams provided.

A+ essay on CRISPR-Cas9, describing the mechanisms, uses and future applications of this technology such as antibiotic resistance.

Biologic drugs - including CAR-T cancer therapy, monoclonal antibodies, and insulin

Pharmacogenomics sample essays. Pharmacogenomics is the use of genetic information from an individual to inform their choice of drug therapy - notes including csRNA-seq, PCR, RFLP, western blotting.

Contains notes on stem cells, with detail on transcription factors Oct, Sox and Nanog, pluripotency, and therapeutic potential.