MTM-Final Exam Basic Science



Ionized forms like A- and BH+ are ________ and ______ diffusible across membrane

water; poorly

generic equation used to calculate week acidic and basic drugs

10 ^(pka-pH) = protonated/unprotonated

equation to calculate weak acidic drugs

10^(pka-pH) = [nonionized(HA)]/[ionized(A-)]

equation to calculate weak basic drugs

10^(pka-pH) = [ionized (BH+)]/[nonionized(B0]

if the pka and pH difference is 1 or -1: ionization is

90% or 10%

if the pka and pH differe...
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