SBRT lung fractionation - ANS 6-30 Gy in 1-5fx



5 Fx x 10 Gy

4 Fx x 12 Gy

3 Fx x 20 Gy



Dose heterogeneity - ANS 1. Overlapping beams with tight margin will put high doses in the center of the target.

2. High Doses in Center may not help radiobiologically but there is no particular disadvantage.

3. Higher dose of radiation administered anywhere within the tumor will enhance the composite cytotoxic effect of and increase the TCP.

4. EUD (Equivalent Uniform Dose) is more rob...
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