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Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Burkitt's Lymphoma Treatment -Rituximab 
CML Treatment -Imatinib, Busulfan 
GI Stromal Tumors Treatment -Imatinib 
HER-2 Positive Breast Cancers Treatment -Trastuzumab 
Acute Coronary Artery Syndrome monoclonal antibody treatment -Anciximab 
PCTA treatment (percutaneous transluminal coronary angioplasty) -Anciximab 
What must be monitored in treatment with Itraconazole? -Liver enzymes 
Tinea versicolor treatment -Topical ketoconazole or selenium
Examen
COMLEX Level 3 Questions and answers 
Diagnostic modality of choice for retropharyngeal abscess -Contrast-enhanced CT of the neck 
Prophylactic treatment for cluster headaches -Verapamil, prednisone, valproic acid, topiramate 
and ergotamine 
Acute treatm
NuevoCOMLEX Level 3 Questions and answers 
Diagnostic modality of choice for retropharyngeal abscess -Contrast-enhanced CT of the neck 
Prophylactic treatment for cluster headaches -Verapamil, prednisone, valproic acid, topiramate 
and ergotamine 
Acute treatment for cluster headaches -100% oxygen (1st line), oral sumatriptan (or SQ) and 
intranasal lidocaine 
Appearance of strep species on Gram stain -Gram-positive cocci in chains 
Appearance of staph species on Gram stain -Gram-positive cocci in cl...
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Opiate withdrawal signs -*yawning 
piloerection 
mydriasis 
diarrhea 
cocaine withdrawal signs -heavy sleeping 
increased appetite 
depression 
tremors/chills 
timing of symptoms in alcohol withdrawal 
- 12 hours 
- 48 hours 
- by 7 days -- tremors, HA, diaphoresis 
- SEIZURES, HTN, agitation 
- hallucinations, DTs (mortality 15-20%)
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Describe the differences between Alcoholic Hallucinosis and Delirium Tremens 
- Alcoholic Hallucinosis = occurs within 12-48 hrs after last drink resulting in hallucination, but with 
NORMAL vitals 
- Delirium Tremens = occurs 48-96 hrs (2-3 days) after last drink with psychomotor agitation, 
tachycardia, hypertension, fever, and/or diaphoresis 
What does the Superior Laryngeal Nerve innervate? 
Cricothyroid Muscle 
What innervates the vocal cords? 
Recurren...
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Vitamin C Deficiency -Everything *normal* in coag panel 
Normal PT 
Normal PTT 
Normal Bleeding Time 
Normal Platelet Count 
Hemophilia A (X-linked recessive disorder) -AKA Factor VIII deficiency - i.e. intrinsic pathway will 
be dysfunctional. Same effect as pts receiving heparin. 
Pts. receiving receiving Warfarin will have extrisinc pathway affected - i.e. increased PT 
Normal PT 
Increased PTT 
Normal Bleeding Time 
Normal Platelet Count 
Von Willbrand D...
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
SBS movement flexion equivalent of sacral movement is... -Couternutation (sacral extension) 
SBS movement extension equivalent of sacral movement is... -Nutation (sacral flexion) 
Epidural hematoma caused by what rupture and scenario, presenting signs? Imaging finding is? - 
Middle meningeal a. after trauma to the head such as in car accident or fight. LOC followed by 
lucid interval followed by comatose episode. CT w/o contrast will show convex lens shaped ...
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Kawasaki Disease 
- Medium vessel vasculitis mainly affecting children under 5 
- 25% can develop coronary artery aneurysms, require echo at diagnosis 
- 5 days of fever + four criteria 
(1) conjunctivitis*** (different from scarlet fever) 
(2) "strawberry tongue" or cracked lips 
(3) maculopapular rash 
(4) edema of hands + feet, desquamating palms + soles 
(5) unilateral painful cervical lymphadenopathy 
- anemia, thrombocytosis, leukocytosis, increa...
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Calcium oxalate -MC type of kidney stone 
Rasburicase -Administration of this drug before chemotherapy can prevent the nephrotoxicity 
associated with tumor lysis syndrome 
Allopurinol -What can be used if rasburicase is contraindicated (due to G6PD def)for prophylaxis 
for tumor lysis syndrome? 
Heart sound in ASD -wide, fixed, and split s2and systolic ejection murmur at the left upper 
sternal border 
Facticious hypoglycemia lab values -Low c-peptide and p...
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
What to expect after administration of methotrexate? -Can have increase in bhcg in day 1-4 but 
between 4-7 should have 15% decrease, if not administer second dose 
How to treat nursemaid's elbow -Flex elbow to 90 degrees and hyperpronate 
Iron overload increases risk of what micro -Vibrio 
Translation is -Opposite sidebending 
Tx for epidural hematoma with mental decline -Neurosurgery 
Lumbar Points -2-4 F SA RT 
PE causes what acid base -Mixed metabolic...
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Vitamin C Deficiency -Everything *normal* in coag panel 
Normal PT 
Normal PTT 
Normal Bleeding Time 
Normal Platelet Count 
Hemophilia A (X-linked recessive disorder) -AKA Factor VIII deficiency - i.e. intrinsic pathway will 
be dysfunctional. Same effect as pts receiving heparin. 
Pts. receiving receiving Warfarin will have extrisinc pathway affected - i.e. increased PT 
Normal PT 
Increased PTT 
Normal Bleeding Time 
Normal Platelet Count 
Von Willbrand D...
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Diverticulitis: 
1) Triad 
2) Method of dx 
3) What exams are contraindicated? 
4) Follow up? -1) LLQ pain, fever, leukocytosis (also tachy) 
2) CT of abdomen 
3) Colonoscopy or barium enema = risk of perforation 
4) Colonoscopy (after resolution), rec high fiber diet 
Features of beta-blocker overdose... TX? -Bradycardia, hypotension, dizziness, fatigue 
TX = glucagon, atropine, IVF 
Leukemia pathognomonic features: 
1) CML [TX?] 
2) CLL 
3) AML 
4) ALL -1)...
Examen
Comlex level 3 OMM Questions and answers
NuevoComlex level 3 OMM Questions and answers 
Sinus chapmans point -Ant: Inferior to the medial Clavicle 
Post: C2 
Pharynx chapmans point -Ant: Inf. to SCM 
post: C2 
Tonsils chpamans: -Ant: Medial 2nd ribs or between ribs 1-2 next to sternum. 
Post: C1 
Middle ear chapmans: -Ant: Superior to medial clavicles , lateral to first rib 
Post: C1 posterior pubic rami (Transverse process of C1) 
Chapmans: Esophagus, thyroid, heart -
Examen
COMLEX Level 3 complete Questions and 
answers
NuevoCOMLEX Level 3 complete Questions and 
answers 
Vitamin C Deficiency 
Everything normal in coag panel 
Normal PT 
Normal PTT 
Normal Bleeding Time 
Normal Platelet Count 
Hemophilia A (X-linked recessive disorder) 
AKA Factor VIII deficiency - i.e. intrinsic pathway will be dysfunctional. Same effect as pts receiving 
heparin. 
Pts. receiving receiving Warfarin will have extrisinc pathway affected - i.e. increased PT 
Normal PT 
Increased PTT 
Normal Bleeding Time 
Normal Platelet Count 
Von Wil...
Examen
Comlex-Usa Actual Exam Questions And Correct Answers With Complete Rationales 2026.
NuevoComlex-Usa Actual Exam Questions And 
Correct Answers With Complete Rationales 
2026.
Lote
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
E. Coli (ETEC) - Epi: recent travel 
Presentation: watery diarrhea 
Labs: 
Treatment: 
E. Coli (EHEC) - Epi: undercooked beef (hamburger) 
Presentation: bloody diarrhea - a/w HUS 
Labs: 
Treatment: do NOT give platelet transfusions or antibiotics 
Giardia - Epi: contaminated water (eg from a stream, camping) - MSM 
Presentation: Watery diarrhea; bloating, flatus, steatorrhea 
Labs: stool ELISA antigen > 90% sens/spec
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Opiate withdrawal signs - *yawning 
piloerection 
mydriasis 
diarrhea 
cocaine withdrawal signs - heavy sleeping 
increased appetite 
depression 
tremors/chills 
timing of symptoms in alcohol withdrawal - 12 hours - 48 hours - by 7 days - - tremors, HA, diaphoresis - SEIZURES, HTN, agitation - hallucinations, DTs (mortality 15-20%) 
epiglottitis - s/s - MC organism - - muffled vo
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Vitamin C Deficiency - Everything *normal* in coag panel 
Normal PT 
Normal PTT 
Normal Bleeding Time 
Normal Platelet Count 
Hemophilia A (X-linked recessive disorder) - AKA Factor VIII deficiency - i.e. intrinsic pathway will 
be dysfunctional. Same effect as pts receiving heparin. 
Pts. receiving receiving Warfarin will have extrisinc pathway affected - i.e. increased PT 
Normal PT 
Increased PTT 
Normal Bleeding Time 
Normal Platelet Count
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Burkitt's Lymphoma Treatment - Rituximab 
CML Treatment - Imatinib, Busulfan 
GI Stromal Tumors Treatment - Imatinib 
HER-2 Positive Breast Cancers Treatment - Trastuzumab 
Acute Coronary Artery Syndrome monoclonal antibody treatment - Anciximab 
PCTA treatment (percutaneous transluminal coronary angioplasty) - Anciximab 
What must be monitored in treatment with Itraconazole? - Liver enzymes 
Tinea versicolor treatment - Topical ketoconazole or se...
Examen
COMLEX Level 3 Questions and answers
NuevoCOMLEX Level 3 Questions and answers 
Diagnostic modality of choice for retropharyngeal abscess - Contrast-enhanced CT of the neck 
Prophylactic treatment for cluster headaches - Verapamil, prednisone, valproic acid, topiramate 
and ergotamine 
Acute treatment for cluster headaches - 100% oxygen (1st line), oral sumatriptan (or SQ) and 
intranasal lidocaine 
Appearance of strep species on Gram stain - Gram-positive cocci in chains 
Appearance of staph species on Gram stain - Gram-positive...