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CMB2001 Questions and Answer | Latest Update 2024/2025
CMB2001 Questions and Answer | Latest Update 2024/2025
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CMB2004 Questions and Answer | Latest Update 2024/2025
Are B and T lymphocytes part of the adaptive or innate immune response? ~~> Adaptive it is the immune memory evolved over time What is the clonal selection theory? ~~> Immature lymphocytes that could self find are destroyed Mature naive lymphocytes are mature until they are exposed to antigens What are the two types of B receptor? ~~> Membrane bound And released from membrane they are known as antibodies T cell receptors are only membrane bound and are formed of what hete...
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CMB2001 – 9 Questions and Answer | Latest Update 2024/2025
how many proteins are in small subunit of the 70S ribosome ~~> 21 how many proteins are in small subunit of the 80S ribosome ~~> 33 how many proteins are in large subunit of the 70S ribosome ~~> 31 how many proteins are in large subunit of the 80S ribosome ~~> 50 23S and 5S rRNA make up the large subunit of the ribosome in ...... ~~> prokaryotes 28S, 5.8S and 5S rRNA make up the large subunit of the ribosome in ...... 2 | P a g e | © copyright 2024/2025 | Grade A+...
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CMB2001 Questions and Answer | Latest Update 2024/2025
Consensus sequences are described with IUPAC ambiguous nucleotide codes. What is a promoter? ~~> DNA sequence which RNA polymerase can bind to and transcribe the protein Prokaryotic promoters ~~> TATAAT -(10 region) 'Pribnow box' TTGACA - (-35 region) - two consensus sequences Prokaryotic RNA polymerase ~~> 1 RNA Polymerase makes all 3 kinds of RNA Composed of 5 subunits, four comprise the core enzyme What is the core enzyme? 2 | P a g e | © copyright 2024/2025 | Gr...
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CMB2001 Questions and Answer | Latest Update 2024/2025
Eukaryotic promoters have a basal region which can contain a TATA box, initiator (Lnr), BRE (TFIIV recognition element) and what other element? ~~> Downstream core promoter (DPE) In prokaryotes RNA polymerase requires what co-factor? ~~> 70 sigma factor Forms the holoenzyme The promoter is formed of two hexameric sequences at what positions? ~~> -35 and -10 The amount of product transcribed is dependant on how close the promoter sequences are to what? ~~> Consensus s...
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CMB2001 Questions and Answer | Latest Update 2024/2025
Why does RNA degradation take place? ~~> Damaged mRNA Incorrectly transcribed/processed mRNA Control gene expression What 2 things control mRNA levels? ~~> Transcription and turnover Why is turnover important? ~~> If mRNA has a ridiculously long half life and doesn't go away, then if you stop transcription you don't stop protein expression because the mRNA is still there Describe what casein mRNA is and explain the importance of turnover ~~> Expressed in mammar...
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CMB2001 Questions and Answer | Latest Update 2024/2025
Core Promoter Elements ~~> TATA box = repetitive sequence of thymine and adenine Initiator (INR) = sequence of pyramidines like thymine and cytosine DPE = downstream promoter elements found along the DNA Common to have >1 promoter but not all of them CpG islands ~~> Sequences high in CG frequency. They are able to escape methylation which would lead to gene silencing. Demethylation would lead to over expression of genes. Regulatory Promoter Elements ~~> UAS and URS f...
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CMB2001 Questions and Answer | Latest Update 2024/2025
What is gene expression? ~~> dsDNA is decoded to ssRNA/proteins by an mRNA intermediate using A/U/C/GTPs and RNA polymerase Where is the consensus sequence in prokaryotic promoters? ~~> at -10 and -35 upstream of the the transcription start site What recognises the consensus sequences in prokaryotes? ~~> the holoenzyme What is a holoenzyme? ~~> a closed complex with a core enzyme and sigma factor 70 What does the holoenzyme do? ~~> causes the dsDNA to open and allo...
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CMB2001 Questions and Answer | Latest Update 2024/2025
Describe how H3Lys9me heterochromatin is formed ~~> H3Lys9me heterochromatin formation: Lys9 deacetylated by HDAC. Suvar39 then methylates lys9. Methylated lys9 is recognised by HP1 and then HP1 binds. HP1 has chromodomain - chromodomains often recognise and bind to methylated lys residues. Chromodomain on HP1 is specific for H3Lys9me (with di or tri methylated lys 9). Binding of HP1 is thought to compact nucleosome arrays as HP1s join together. What is gene expression? ~~> ...
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CMB2001 L01 Questions and Answer | Latest Update 2024/2025
Consensus sequences are described with IUPAC ambiguous nucleotide codes. W is A or T S is G or C R is G or A Y is T or C What is the span of the core/basal region of the eukaryotic promoter? ~~> -30 to +30nt What elements are in the core region of the eukaryotic promoter? ~~> TATA box Inr (initiator) DPE (downstream promoter element) BRE (TFIIB recognition element) 2 | P a g e | © copyright 2024/2025 | Grade A+ Master01 | September, 2024/2025 | Latest update Describe th...
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CMB2004 Questions and Answer | Latest Update 2024/2025
What is a pathogen? ~~> A microorganism that causes disease e.g. bacteria, fungi, virus, parasite For an effective immune response the immune system must... ~~> - be able to recognise and respond to any invading organism - not over react to benign or self - be able to direct different effector mechanisms against different pathogens What is specific/adaptive immunity? ~~> - it is induced by exposure to a particular infection - shows a high degree of specificity - exhib...
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CMB2001 Exam Exam Package Deal
CMB2001 Exam Exam Package Deal
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CMB2001 Exam Questions With Verified Answers
CMB2001 Exam Questions With Verified Answers What is a promoter? - answerDNA sequence which RNA polymerase can bind to and transcribe the protein Prokaryotic promoters - answerTATAAT -(10 region) 'Pribnow box' TTGACA - (-35 region) - two consensus sequences Prokaryotic RNA polymerase - answer1 RNA Polymerase makes all 3 kinds of RNA Composed of 5 subunits, four comprise the core enzyme What is the core enzyme? - answerHelps to initiate and synthesize RNA. 4 main polypeptides (2 alpha...
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CMB2001 Exam Questions With Verified Answers.
CMB2001 Exam Questions With Verified Answers. What is gene expression? - answerdsDNA is decoded to ssRNA/proteins by an mRNA intermediate using A/U/C/GTPs and RNA polymerase Where is the consensus sequence in prokaryotic promoters? - answerat -10 and -35 upstream of the the transcription start site What recognises the consensus sequences in prokaryotes? - answerthe holoenzyme What is a holoenzyme? - answera closed complex with a core enzyme and sigma factor 70 What does the holoenzyme do...
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CMB2001 Exam Questions With Verified Answers
CMB2001 Exam Questions With Verified Answers In prokaryotes RNA polymerase requires what co-factor? - answer70 sigma factor Forms the holoenzyme The promoter is formed of two hexameric sequences at what positions? - answer-35 and -10 The amount of product transcribed is dependant on how close the promoter sequences are to what? - answerConsensus sequence Eukaryotic promoters have a basal region which can contain a TATA box, initiator (Lnr), BRE (TFIIV recognition element) and what other ...
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CMB2001 Exam Questions With Verified Answers.
CMB2001 Exam Questions With Verified Answers. Core Promoter Elements - answerTATA box = repetitive sequence of thymine and adenine Initiator (INR) = sequence of pyramidines like thymine and cytosine DPE = downstream promoter elements found along the DNA Common to have >1 promoter but not all of them CpG islands - answerSequences high in CG frequency. They are able to escape methylation which would lead to gene silencing. Demethylation would lead to over expression of genes. Regulatory...
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CMB2001 Exam Questions With Verified Answers.
©THEBRIGHTSTARS 2024 CMB2001 Exam Questions With Verified Answers. Describe how H3Lys9me heterochromatin is formed - answerH3Lys9me heterochromatin formation: Lys9 deacetylated by HDAC. Suvar39 then methylates lys9. Methylated lys9 is recognised by HP1 and then HP1 binds. HP1 has chromodomain - chromodomains often recognise and bind to methylated lys residues. Chromodomain on HP1 is specific for H3Lys9me (with di or tri methylated lys 9). Binding of HP1 is thought to compact nucleosome a...
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CMB2001 Exam Questions With Verified Answers
CMB2001 Exam Questions With Verified Answers Why does RNA degradation take place? - answerDamaged mRNA Incorrectly transcribed/processed mRNA Control gene expression What 2 things control mRNA levels? - answerTranscription and turnover Why is turnover important? - answerIf mRNA has a ridiculously long half life and doesn't go away, then if you stop transcription you don't stop protein expression because the mRNA is still there Describe what casein mRNA is and explain the importance of...
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CMB2001 – 9 Exam Questions With Verified Answers.
CMB2001 – 9 Exam Questions With Verified Answers. 21 - answerhow many proteins are in small subunit of the 70S ribosome 33 - answerhow many proteins are in small subunit of the 80S ribosome 31 - answerhow many proteins are in large subunit of the 70S ribosome 50 - answerhow many proteins are in large subunit of the 80S ribosome prokaryotes - answer23S and 5S rRNA make up the large subunit of the ribosome in ...... eukaryotes - answer28S, 5.8S and 5S rRNA make up the large subunit of the...
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Cmb2001/Cmb 2001 Bundled Current Exams With Questions And 100 % Verified Answers
Cmb2001/Cmb 2001 Bundled Current Exams With Questions And 100 % Verified Answers ...
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