MN 551 Pathophisiology

Discuss pathophysiology of coronary artery disease (CAD). • Coronary Arteries: Supply blood to the heart o Atherosclerosis – plaque formation on artery walls  Plaque formation starts forming in early adulthood  Usually forms in the bigger vessels  Coronary artery beds, aorta, carotids, vertebral, renal, femoral  Protrudes into lumen, partially or completely obstructing blood flow  Leading factor in cardiovascular disease  Fibrotic plaques become calcified, hemorrhagic, ulce...