Dna damage - Samenvattingen en Aantekeningen
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Samenvatting
Summary Molecular and Cellular Toxicology (XM_0113)
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5.0(2)5.01468december 20232023/2024
- This document consists of a summary of the course Molecular and Cellular Toxicology, corresponding to the Master Drug Discovery Sciences.
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€8,99 Meer Info
danielleband
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Tentamen (uitwerkingen)
Exam (elaborations) NURS 4010 COMPREHENSIVE TEST BANK 2024- 2025 FINAL
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---33oktober 20242024/2025A+
- Exam (elaborations) NURS 4010 COMPREHENSIVE TEST BANK FINAL exam latest version 
How do radiotherapy work? 
causes double helical-strand breaks in molecules; results in lethal (cell 
death) or sublethal (injured cells capable of subsequent repair) 
damage→ contributes to late effects (depending on body part treated, 
dosage, and age of the child at tx) 
MOA of chemo: Alkylating Agent 
replace hydrogen atom of molecule by alkyl group→ unbalanced growth 
of unaffected cell constituents a...
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€22,90 Meer Info
NURSEGENERAL
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Tentamen (uitwerkingen)
TEST BANK FOR UNDERSTANDING PATHOPHYSIOLOGY, 5TH EDITION HUETHER AND MCCANCE ISBN;9780729581608 ALL CHAPTERS COVERED WITH VERIFIED QUESTIONS AND ANSWERS GRADED A+||NEWEST VERSION.
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---1176augustus 20252025/20269-10
- TEST BANK UNDERSTANDING PATHOPHYSIOLOGY, 5TH EDITION HUETHER AND MCCANCE Chapter 01: Cellular Biology Chapter 01: Cellular Biology Chapter 01: Cellular Biology Chapter 01: Cellular Biology Chapter 01: Cellular Biology Chapter 01: Cellular Biology Chapter 01: Cellular Biology Chapter 01: Cellular Biology Chapter 01: Cellular Biology Huether and McCance: Understanding Pathophysiology, 5th Edition Chapter 01: Cellular Biology Test Bank MULTIPLE CHOICE 1. A student is observing a cell under the micr...
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€17,06 Meer Info
Brainbox
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Samenvatting
Medical Cell Biology - University of Groningen - Complete Lecture Summary
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---23februari 20262025/2026
- This document provides a comprehensive summary of the Medical Cell Biology course, covering key topics from cell junctions and epithelial biology to neurodegeneration and radiobiology. It includes detailed explanations of cellular trafficking, multiple sclerosis, oligodendrocyte biology, DNA damage responses, ageing, proteostasis, autophagy, Huntington’s disease, regenerative responses to radiation and much more. The summary follows the structure of the lectures and is suitable for exam prepar...
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€4,49 Meer Info
wouterolderode
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Tentamen (uitwerkingen)
CBT QUESTIONS AND ACCURATE PASSED ANSWERS 2023/2024
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---15februari 20242023/2024A+
- CBT QUESTIONS AND ACCURATE PASSED ANSWERS 2023/2024 
 
Which one of the following statements correctly describes what happens after Wnt ligand binds to Frizzled and LRP? 
 
a. RAR-RXR heterodimers are formed and associate with HDAC co-repressor complexes, silencing target genes. 
b. Axin and APC form a complex with CKI and GSK3β which then modifies β-catenin for degradation. 
c. Axin is recruited to the phosphorylated co-receptor LRP and this disrupts the APC, CKI, GSK3β complex. 
d. Patched ...
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€12,57 Meer Info
KieranKent55
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Samenvatting
Molecular Toxicology
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---50september 20252025/2026
- This is a summary of molecular toxicology based on Boelsterli, U. A. (2007). Mechanistic Toxicology: The Molecular Basis of How Chemicals Disrupt Biological Targets. It covers the molecular mechanisms by which chemicals and drugs can cause toxicity in humans and animals. 
 
Topics include: 
 
Basic principles of toxicology: dose-dependence, exposure routes, toxicokinetics (absorption, distribution, metabolism, excretion) and toxicodynamics (interaction with cellular targets). 
 
Biological resp...
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€8,48 Meer Info
marelilya
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College aantekeningen
College aantekeningen Cellulaire Oncologie (5052CEO12Y)
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--280november 20232020/2021
- Samenvatting van de colleges Cellulaire oncologie. Tijdens het tweede jaar van de bachelor Biomedische Wetenschappen bij de UvA. Eerste college en een deel van het tweede college zijn in het nederlands, de rest is in het engels
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€7,50 Meer Info
lucavaneick
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College aantekeningen
Biology of Cancer
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4.0(1)4.0147april 20222019/2020
- Summary that includes all lectures given by Schuringa, Van Vught, Kruyt and de Jong.The topics of the lectures are: carcinogenesis, cancer stem cells, the role of oncogenes and tumor suppressor genes, the large variety of subtypes within hematological and solid tumors, the signaling pathways active in different tumor types, genetic regulation of these molecular pathways (epigenetics, miRNA), DNA damage response, the tumormicroenvironment , the process of metastasis, tumor immunology, therapeutic...
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€8,49 Meer Info
aniekvlasma
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Tentamen (uitwerkingen)
4) Exposure of DNA to oxidizing agents can result in the oxidation of
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---1juni 20232022/2023A
- 4) Exposure of DNA to oxidizing agents can result in the oxidation of G residues in the DNA 
resulting in the formation 8-oxoG. This damage is highly mutagenic since 8- oxoG can pair with 
A, which leads to a G to T transversion mutation. This type of mutation frequently occurs in 
tumor suppressor genes such as p53 leading to cancer. The 8-oxoG:A H2N basepair has the 
structure shown on the right. Note that this basepair can only form if the glycosidic bond to the 
8-oxoG is in the syn conforma...
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€6,99 Meer Info
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