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ANCC Test Review 2025 – Complete Study Guide & Practice Questions

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Prepare for your ANCC certification exam with this 2025 comprehensive study guide. Includes complete review of key topics, high-yield concepts, and realistic practice questions with answers to help nurses and nurse practitioners succeed on the exam efficiently.

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ANCC Test Review – Complete Study Guide
& Practice Questions 2025




A patient with type1 diabetes mellitus who is NPH and regular insulin split dosing present with
complains of early morning rise finger-stick blood glucose. A review of an at-home glucose test reveals
increased morning levels. After an increase in the evening insulin dose, the problem worsens. This is
most likely an example of:



a) Insulin Resistance

b) Insulin Allergy

c) The Somogyi Effect

d) Hyperglycemia-induced hypoglycemia. ANSWER ✨✔---a) The Somogyi Effect



A 25-years-old present with a chief complaint of decreased mobility and pain of the right shoulder
exacerbated by movements. The patient reports that he participated in extensive house painting 24
hours prior to the onset of pain. He denies any trauma. Passive ROM is intact. No redness or ecchymosis
is present. What is the next step to be taken in order to make a Diagnosis?



a) Palpate the structure around the shoulder

b) Obtain an MIR to evaluate the shoulder

c) Order and X-Ray of the shoulder

d) Request an EMG

,Apply SOAPE ANSWER ✨✔---a) Palpate the structure around the shoulder

Apply SOAPE



A 65 years-old male presents to his clinic complaining of increasing fatigue, dyspnea on exertion ,and
ankle edema during the day. He has a history of mild hypertension, for which he saw his physician years
ago. The physician advised the patient to decrease his salt intake .On physician examination the patient
is tachycardia positive for jugular venous distension, and positive for S3 with a systolic murmur chest X-
ray reveals cardiomegaly with vascular redistribution .The nurse practitioner diagnosis is :



a) Myocardial infarction

b) Pneumonia

c) Congestive heart failure

d) Pleural effusion ANSWER ✨✔---c) Congestive heart failure



A 67-year old patient with type 2 DM, congestive heart failure (CHF), and a mild artery disease is
currently taking daily hydrochlorothiazide 25 mg daily, glipizide 10 mg daily; and atorvastatin (Lipitor),
20 mg h.s. Which of the following is an accurate statement regarding this regimen?



a) The glipizide will increase the risk of potassium depletion....

b) The digoxin will increase the risk of hypoglycemia.

c) The hydrochlorothiazide will predispose the patient to digoxin toxicity

d) The atorvastin will worsen the diabetes ANSWER ✨✔---c) The hydrochlorothiazide will
predispose the patient to digoxin toxicity



A 14 year-old who fell on her outstretched hand complains of proximal forearm pain X-ray reveals a
positive fat pad sign ,and the fully extend the elbow. No definitive bony changes are seen on X-ray. The
most likely working diagnosis is:



a) Upper extremely sprain.

b) Lateral epiconditis.

c) Radial head fracture

d) Olecranon bursitis ANSWER ✨✔---c) Radial head fracture

,A 17 year-old female is suspected to have a Polycystic Ovary Syndrome. In addition to testosterone the
most appropriate diagnostic test will be:



a) BUN, creatinine, electrolytes, and denydroeplandrosterone (DHEA).

b) Complete blood count (BUN) ,creatinine and estrone

c) Fasting blood sugar(FBS) ,CBC, BUN and sex hormone binding globuline

d) Follicle stimulating hormone (FSH) luteinizing hormone, prolactin, and thyroid stimulating hormone
(TSH) ANSWER ✨✔---d) Follicle stimulating hormone (FSH) luteinizing hormone, prolactin, and
thyroid stimulating hormone (TSH)



To assess spinal function at S1-level, which deep tendon reflex should be tested?



a) Achilles

b) Cremasteric

c) Anal wink

d) Patelar ANSWER ✨✔---a) Achilles



A 20 year-old male present with a month history of a "bump on my testicle." He reports being sexually
active, with frequent intercourse with multiple partners, which condition should be suspected?



a) Cancer of testicles

b) Torsion of the testicles

c) Acute epididymitis

d) Gonorrhea ANSWER ✨✔---a) Cancer of testicles



An 88 year-old male presents with concerns about memory loss .He feels good, takes aspirin daily ,and
has no chronic diseases ,he drives his own car ,and manages his financial affairs .To evaluate his memory
,which of the fallowing tests would you choose?



a) Folstein Mini- Mental-State Examination.

, b) Geriatric Depression Scale

c) Minnesota Multiphasic personality inventory

d) Myers -Briggs Test ANSWER ✨✔---a) Folstein Mini- Mental-State Examination



Nonviral Microorganisms most frequently found to cause acute sinusitis are:



a) Streptococcus pneumonie and Haemophilus influenzae

b) Streptococcus pneumonie and staphylococcus aureus

c) Staphylococcus aureus and Pseudomonas aeruginosa

d) Streptococcus pneumonie and Pseudomonas aeruginosa ANSWER ✨✔---a) Streptococcus
pneumonie and Haemophilus influenzae



A 65-year old female presents with shoulder and pelvic girdle pain for the past 6 months .She reports
recent unintentional weigh loss. On physical examination, there is pain on ROM with no weakness
noted. Laboratory studies show low hemoglobin and elevated sedimentation rate.Which of the
fallowing is the most likely diagnosis?



a) Polymyosistis

b) Osteoarthritis

c) Polymyalgia rheumatic

d) Fibromyalgia ANSWER ✨✔---c) Polymyalgia rheumatic



A 17 year-old female has never had her menses. She is at tanner stage III of sexual development. Her
physical and her weight is appropriate for her age and height. What is the most likely diagnosis?



a) Secondary amenorrhea

b) Primary amenorrhea

c) Dysmenorrhea

d) Ovarian digenesis ANSWER ✨✔---b) Primary amenorrhea

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