NUCLEAR MEDICINE BOARD EXAM
& STUDY GUIDE | NEWEST ACTUAL EXAM
COMPREHENSIVE
QUESTIONS AND VERIFIED ANSWERS
GRADED A+ 2026 UPDATE!
Visualization of the kidneys at 48 hours is _____ on a scan using In-111
pentetreotide and ___ on a Ga67 citrate scan. Normal: abnormal
normal: normal abnormal; normal
abnormal; normal ANSWER Normal: abnormal
A technologist is performing a parathyroid study using MIBI. After the
flow study, the first
phase (thyroid phase) of imaging should begin within ANSWER a. 5
to 10 minutes. b. 15 to 20 minutes.
c. 60 to 90 minutes.
d. 120 minutes.
ANS: B
The first or thyroid phase should begin 15 to 20 minutes after injection;
the second or parathyroid phase should be performed at 2 hours.
,The radionuclide used in the diagnostic evaluation of recurrent or
metastatic colorectal cancer is ANSWER a. 99mTc-sestamibi. b.
99mTc-arcitumomab.
c. 111In-capromab pendetide.
d. 111In-pentetreotide.
ANS: B
99mTc-arcitumomab is a fragmented antibody (Fab) generated from
IMMUJ-4 and reacts with
carcinoembryonic antigen (CEA), a tumor-associated antigen expressed
on a variety of carcinomas found in the gastrointestinal tract.
1. What is the lower limit for circulating granulocyte counts when
imaging with IN WBCs? What is the lower limit for WBC count when
imaging with Tc HMPAO WBCs? ANSWER Lower limit for IN WBCs: 3
times 106 circulating granulocyte cells/mL
Lower limit for WBC imaging with Tc HMPAO WBCs: 3000/mm3 WBC
count
1. Why is 111 In WBCs the RP of choice for imaging infection of the
abdomen? ANSWER In-111 will not appear in the intestines unless it is
positive for infection, unlike 99mTc HMPAO. Therefore, it is the
radiopharmaceutical of choice because it only shows liver/spleen
uptake in the abdomen.
, 1. Name 2 anticoagulants that may be used during WBC tagging and the
dose that is typical. ANSWER 1) Heparin
2) Acid- citrate Dextrose
Typical dose is 4-8mL
1. What is the normal biodistribution of In WBCs? AND for Tc HMPAO
WBCs? ANSWER Biodistribution of In WBCs: Spleen, Liver, Bone marrow
Biodistribution for Tc HMPAO WBCs: Spleen, Liver, Bone marrow,
Kidneys, Bladder, Heart (early images), Lungs (early images), great
vessels (early images)
In imaging with 67Ga-citrate, target-to-background ratio increases over
time because of gallium concentration in tissue ANSWER remaining the
same while blood clearance progresses. b. decreasing while blood
clearance progresses.
c. remaining the same while blood clearance decreases.
d. decreasing while blood clearance decreases
ANS: A
The gallium concentration in tissue remains while the target-
tobackground ratio increases as the blood clearance progresses
over time
A technologist is positioning a patient for a 67Ga-citrate imaging study
and notices that a
& STUDY GUIDE | NEWEST ACTUAL EXAM
COMPREHENSIVE
QUESTIONS AND VERIFIED ANSWERS
GRADED A+ 2026 UPDATE!
Visualization of the kidneys at 48 hours is _____ on a scan using In-111
pentetreotide and ___ on a Ga67 citrate scan. Normal: abnormal
normal: normal abnormal; normal
abnormal; normal ANSWER Normal: abnormal
A technologist is performing a parathyroid study using MIBI. After the
flow study, the first
phase (thyroid phase) of imaging should begin within ANSWER a. 5
to 10 minutes. b. 15 to 20 minutes.
c. 60 to 90 minutes.
d. 120 minutes.
ANS: B
The first or thyroid phase should begin 15 to 20 minutes after injection;
the second or parathyroid phase should be performed at 2 hours.
,The radionuclide used in the diagnostic evaluation of recurrent or
metastatic colorectal cancer is ANSWER a. 99mTc-sestamibi. b.
99mTc-arcitumomab.
c. 111In-capromab pendetide.
d. 111In-pentetreotide.
ANS: B
99mTc-arcitumomab is a fragmented antibody (Fab) generated from
IMMUJ-4 and reacts with
carcinoembryonic antigen (CEA), a tumor-associated antigen expressed
on a variety of carcinomas found in the gastrointestinal tract.
1. What is the lower limit for circulating granulocyte counts when
imaging with IN WBCs? What is the lower limit for WBC count when
imaging with Tc HMPAO WBCs? ANSWER Lower limit for IN WBCs: 3
times 106 circulating granulocyte cells/mL
Lower limit for WBC imaging with Tc HMPAO WBCs: 3000/mm3 WBC
count
1. Why is 111 In WBCs the RP of choice for imaging infection of the
abdomen? ANSWER In-111 will not appear in the intestines unless it is
positive for infection, unlike 99mTc HMPAO. Therefore, it is the
radiopharmaceutical of choice because it only shows liver/spleen
uptake in the abdomen.
, 1. Name 2 anticoagulants that may be used during WBC tagging and the
dose that is typical. ANSWER 1) Heparin
2) Acid- citrate Dextrose
Typical dose is 4-8mL
1. What is the normal biodistribution of In WBCs? AND for Tc HMPAO
WBCs? ANSWER Biodistribution of In WBCs: Spleen, Liver, Bone marrow
Biodistribution for Tc HMPAO WBCs: Spleen, Liver, Bone marrow,
Kidneys, Bladder, Heart (early images), Lungs (early images), great
vessels (early images)
In imaging with 67Ga-citrate, target-to-background ratio increases over
time because of gallium concentration in tissue ANSWER remaining the
same while blood clearance progresses. b. decreasing while blood
clearance progresses.
c. remaining the same while blood clearance decreases.
d. decreasing while blood clearance decreases
ANS: A
The gallium concentration in tissue remains while the target-
tobackground ratio increases as the blood clearance progresses
over time
A technologist is positioning a patient for a 67Ga-citrate imaging study
and notices that a
