GMS 6474: Cardiovascular and Muscle
Physiology Final Exam ACTUAL
QUESTIONS AND CORRECT ANSWERS
The tendon is responsible for... - CORRECT ANSWERS Keeping the
skeletal muscle attached to the bone
The tendon is made up of connective tissue at what three layers? From smallest
to largest groupings. - CORRECT ANSWERS (1) Endomysium
(2) Perimysium
(3) Epimysium
What regulates protein synthesis throughout the muscle cell? - CORRECT
ANSWERS Myonuclei
What type of cells assists in repairing muscle damage? - CORRECT
ANSWERS Satellite Cells
The Isotropic Band (I Band) of the sarcomere is composed of... - CORRECT
ANSWERS Thin Filaments
Titin
Z disk
The A Band of the sarcomere is composed of... - CORRECT ANSWERS
Thin Filaments
Thick Filaments
The H Zone of the sarcomere is composed of... - CORRECT ANSWERS
Only the thick filament without the myosin heads
,During contraction of the sarcomere, what change occurs in the thin and thick
filaments? - CORRECT ANSWERS The amount of overlap between the
two
The SR is responsible for... - CORRECT ANSWERS The storage and
release of Ca++
How does each myofibril have access to the extracellular fluid? - CORRECT
ANSWERS Via the T tubules
Dihydropyridine Receptors (DHPR) are found in the __________ and they are
________ receptors - CORRECT ANSWERS T tubule ; Voltage
Ryanodine Receptors (RyR) are found in the _______ and they are
_______________ channels. - CORRECT ANSWERS SR ; Calcium
Release Channels
The thick filament's molecular structure is composed of what 2 things? -
CORRECT ANSWERS (1) Myosin
(2) Titin
F-actin in the thin filament is... - CORRECT ANSWERS A helix of
globular G actin that exposes an active site in which the myosin head can bind
to
Tropomyosin is a single strand protein that... - CORRECT ANSWERS
Covers the active site fount on F-actin
, The troponin complex in the presence of Ca++ can... - CORRECT ANSWERS
Move tropomyosin to expose the active site of F-actin
CapZ anchors _______ to the ___________ of the sarcomere - CORRECT
ANSWERS Actin ; Z-disk
Dystrophin connects the sarcomere to the _______ & __________. Without it
there would be significant cell damage during contraction - CORRECT
ANSWERS Extracellular fluid; Sarcolemma
The presynaptic membrane contains what two things? - CORRECT ANSWERS
(1) Mitochondria
(2) Acetylcholine Vesicles
What happens during the activation of the presynaptic membrane? - CORRECT
ANSWERS Acetylcholine vesicles fuse and release their contents into
the synaptic cleft
As acetylcholine diffuses across the synaptic cleft, it binds to ___________.
What does this binding lead to an activation of? - CORRECT ANSWERS
Nicotinic Receptors ; Increased Na+/K+ permeability
Standard activation of nicotinic receptors causes? - CORRECT ANSWERS
A shift in membrane potential (-80mV ——> -15mV)
What are the 3 phases of excitation-contraction coupling? - CORRECT
ANSWERS (1) Action Potential Propagation
(2) Ca++ Release
(3) Exposure of Actin Active Sites
Physiology Final Exam ACTUAL
QUESTIONS AND CORRECT ANSWERS
The tendon is responsible for... - CORRECT ANSWERS Keeping the
skeletal muscle attached to the bone
The tendon is made up of connective tissue at what three layers? From smallest
to largest groupings. - CORRECT ANSWERS (1) Endomysium
(2) Perimysium
(3) Epimysium
What regulates protein synthesis throughout the muscle cell? - CORRECT
ANSWERS Myonuclei
What type of cells assists in repairing muscle damage? - CORRECT
ANSWERS Satellite Cells
The Isotropic Band (I Band) of the sarcomere is composed of... - CORRECT
ANSWERS Thin Filaments
Titin
Z disk
The A Band of the sarcomere is composed of... - CORRECT ANSWERS
Thin Filaments
Thick Filaments
The H Zone of the sarcomere is composed of... - CORRECT ANSWERS
Only the thick filament without the myosin heads
,During contraction of the sarcomere, what change occurs in the thin and thick
filaments? - CORRECT ANSWERS The amount of overlap between the
two
The SR is responsible for... - CORRECT ANSWERS The storage and
release of Ca++
How does each myofibril have access to the extracellular fluid? - CORRECT
ANSWERS Via the T tubules
Dihydropyridine Receptors (DHPR) are found in the __________ and they are
________ receptors - CORRECT ANSWERS T tubule ; Voltage
Ryanodine Receptors (RyR) are found in the _______ and they are
_______________ channels. - CORRECT ANSWERS SR ; Calcium
Release Channels
The thick filament's molecular structure is composed of what 2 things? -
CORRECT ANSWERS (1) Myosin
(2) Titin
F-actin in the thin filament is... - CORRECT ANSWERS A helix of
globular G actin that exposes an active site in which the myosin head can bind
to
Tropomyosin is a single strand protein that... - CORRECT ANSWERS
Covers the active site fount on F-actin
, The troponin complex in the presence of Ca++ can... - CORRECT ANSWERS
Move tropomyosin to expose the active site of F-actin
CapZ anchors _______ to the ___________ of the sarcomere - CORRECT
ANSWERS Actin ; Z-disk
Dystrophin connects the sarcomere to the _______ & __________. Without it
there would be significant cell damage during contraction - CORRECT
ANSWERS Extracellular fluid; Sarcolemma
The presynaptic membrane contains what two things? - CORRECT ANSWERS
(1) Mitochondria
(2) Acetylcholine Vesicles
What happens during the activation of the presynaptic membrane? - CORRECT
ANSWERS Acetylcholine vesicles fuse and release their contents into
the synaptic cleft
As acetylcholine diffuses across the synaptic cleft, it binds to ___________.
What does this binding lead to an activation of? - CORRECT ANSWERS
Nicotinic Receptors ; Increased Na+/K+ permeability
Standard activation of nicotinic receptors causes? - CORRECT ANSWERS
A shift in membrane potential (-80mV ——> -15mV)
What are the 3 phases of excitation-contraction coupling? - CORRECT
ANSWERS (1) Action Potential Propagation
(2) Ca++ Release
(3) Exposure of Actin Active Sites
