Pt taking clopidogrel often genotyped for which gene?
Give this one a try later!
CYP2C19
What inherent conflict does the legalization of medical marijuana create with the
federal laws governing controlled substances?
Give this one a try later!
, The federal government can still punish someone with marijuana, even if it's
prescribed to them, even though the state has made it legal. Marijuana is a
schedule 1 controlled substance and under federal law can not be
prescribed.
Aspirin has an ED50= 5 mg/dL and a TD50= 100 mg/dL. What is the therapeutic index
of aspirin?
Give this one a try later!
20
Which term describes a molecule that produces an effect when binding a receptor
but is incapable of inducing a %100 effect?
Give this one a try later!
Partial agonist
Imagine a drug with kEL= 1.2 hours-1, clearance= 14.4 cL/hr, and VD= 12 L/kg. What
loading dose would be required to achieve a 2 mg/L concentration in a 30 kg
patient?
Give this one a try later!
720 mg
, What government agency regulates phase I clinical trails in the US?
Give this one a try later!
FDA
Most drugs bind in such a way that it is reversible without a chemical reaction. These
drugs must therefore lack which type of bond with their targets?
Give this one a try later!
Covalent
What is the name of the process that involves step-wise alteration of a drug to
improve its properties?
Give this one a try later!
Structure activity relationship
A pt with a history of heart disease takes a long vacation where he drinks many pina
coladas. After he returns he suffered a brain hemorrhage. Why?
Give this one a try later!
Give this one a try later!
CYP2C19
What inherent conflict does the legalization of medical marijuana create with the
federal laws governing controlled substances?
Give this one a try later!
, The federal government can still punish someone with marijuana, even if it's
prescribed to them, even though the state has made it legal. Marijuana is a
schedule 1 controlled substance and under federal law can not be
prescribed.
Aspirin has an ED50= 5 mg/dL and a TD50= 100 mg/dL. What is the therapeutic index
of aspirin?
Give this one a try later!
20
Which term describes a molecule that produces an effect when binding a receptor
but is incapable of inducing a %100 effect?
Give this one a try later!
Partial agonist
Imagine a drug with kEL= 1.2 hours-1, clearance= 14.4 cL/hr, and VD= 12 L/kg. What
loading dose would be required to achieve a 2 mg/L concentration in a 30 kg
patient?
Give this one a try later!
720 mg
, What government agency regulates phase I clinical trails in the US?
Give this one a try later!
FDA
Most drugs bind in such a way that it is reversible without a chemical reaction. These
drugs must therefore lack which type of bond with their targets?
Give this one a try later!
Covalent
What is the name of the process that involves step-wise alteration of a drug to
improve its properties?
Give this one a try later!
Structure activity relationship
A pt with a history of heart disease takes a long vacation where he drinks many pina
coladas. After he returns he suffered a brain hemorrhage. Why?
Give this one a try later!
