Nursing Pharmacology Questions And
Verified Answers /100% Correct /Grade
A+ 2025
Absorption - ANSWER-the process by which drug molecules move from their site of administration to
the blood
Affinity - ANSWER-the ability of some tissues to attract, accumulate and store drugs in high
concentrations relative to other tissues
blood-brain barrier - ANSWER-Blood vessels (capillaries) that selectively let certain substances enter the
brain tissue and keep other substances out
diffusion - ANSWER-process by which molecules tend to move from an area where they are more
concentrated to an area where they are less concentrated
distribution - ANSWER-the transport of drugs throughout the body after they are absorbed
drug-protein complexes - ANSWER-formed when a drugh that binds reversibly to a plasma protein,
particularly albumin, that makes the drug unavailable for distribution to its site of action
enterohepatic recirculation - ANSWER-recycling of drugs and other substances by the circulation of bile
through the intestine and liver
enzyme induction - ANSWER-process by whick a drug increases the activity of the hepatic microsomal
enzymes
excretion - ANSWER-the process of removing substances from the body
first-pass effect - ANSWER-mechanism whereby drugs are absorbed enter into the hepatic portal
circulation and are inactivated by the liver before they reach the general circulation
, fetal-placental barrier - ANSWER-special anatomic barrier that inhibits many chemicals and drugs from
entering the fetus
hepatic microsomal enzyme system - ANSWER-as it relates to phamacotherapy, liver enzymes that
metabolize drugs as well as nutrients and other endogenous substances, sometimes called the P-450
System
isozymes - ANSWER-multiple similar forms of an enzyme that perform slightly different metabolic
functions
loading dose - ANSWER-relatively large dose of a drug given at the beginning of treatment to rapidly
obtain a therapeutic response
maintenance doses - ANSWER-amount of drug that keeps the plasma drug concentration in the
therapeutic range
metabolism - ANSWER-the process used by the body to chemically change a drug molecule, also called
biotransformation
minimum effective concentration - ANSWER-amount of drug required to produce a therapeutic effect
pharmacokinetics - ANSWER-study of drug movement throughout the body
plasma half-life - ANSWER-the length of time required for the plasma concentration of a drug to
decrease by one half after administration
prodrugs - ANSWER-drugs that become more active after they are metabolized
substrate - ANSWER-drug that is metabolized by a CYP enzyme
therapeutic drug monitoring - ANSWER-practice of monitoring plasma levels of drughs that have low
safety profiles and using the data to predict drugh action or toxicity
Verified Answers /100% Correct /Grade
A+ 2025
Absorption - ANSWER-the process by which drug molecules move from their site of administration to
the blood
Affinity - ANSWER-the ability of some tissues to attract, accumulate and store drugs in high
concentrations relative to other tissues
blood-brain barrier - ANSWER-Blood vessels (capillaries) that selectively let certain substances enter the
brain tissue and keep other substances out
diffusion - ANSWER-process by which molecules tend to move from an area where they are more
concentrated to an area where they are less concentrated
distribution - ANSWER-the transport of drugs throughout the body after they are absorbed
drug-protein complexes - ANSWER-formed when a drugh that binds reversibly to a plasma protein,
particularly albumin, that makes the drug unavailable for distribution to its site of action
enterohepatic recirculation - ANSWER-recycling of drugs and other substances by the circulation of bile
through the intestine and liver
enzyme induction - ANSWER-process by whick a drug increases the activity of the hepatic microsomal
enzymes
excretion - ANSWER-the process of removing substances from the body
first-pass effect - ANSWER-mechanism whereby drugs are absorbed enter into the hepatic portal
circulation and are inactivated by the liver before they reach the general circulation
, fetal-placental barrier - ANSWER-special anatomic barrier that inhibits many chemicals and drugs from
entering the fetus
hepatic microsomal enzyme system - ANSWER-as it relates to phamacotherapy, liver enzymes that
metabolize drugs as well as nutrients and other endogenous substances, sometimes called the P-450
System
isozymes - ANSWER-multiple similar forms of an enzyme that perform slightly different metabolic
functions
loading dose - ANSWER-relatively large dose of a drug given at the beginning of treatment to rapidly
obtain a therapeutic response
maintenance doses - ANSWER-amount of drug that keeps the plasma drug concentration in the
therapeutic range
metabolism - ANSWER-the process used by the body to chemically change a drug molecule, also called
biotransformation
minimum effective concentration - ANSWER-amount of drug required to produce a therapeutic effect
pharmacokinetics - ANSWER-study of drug movement throughout the body
plasma half-life - ANSWER-the length of time required for the plasma concentration of a drug to
decrease by one half after administration
prodrugs - ANSWER-drugs that become more active after they are metabolized
substrate - ANSWER-drug that is metabolized by a CYP enzyme
therapeutic drug monitoring - ANSWER-practice of monitoring plasma levels of drughs that have low
safety profiles and using the data to predict drugh action or toxicity
