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NR507 MID-TERM EXAM (CHAMBERLAIN) NEWEST
2025 ACTUAL EXAM| NR507 ADVANCED
PATHOPHYSIOLOGY MID-TERM EXAM WITH 200 REAL
EXAM QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) ALREADY GRADED A+ (BRAND
NEW!!)
Asthma .....ANSWER..... A chronic allergic disorder characterized
by episodes of severe breathing difficulty, coughing, and
wheezing.
What is constricted in asthma? .....ANSWER..... Bronchi
Early asthmatic response .....ANSWER..... Antigen exposure to
bronchial mucosa activates dendritic cells to present the antigen
to CD4+ Tcells, which differentiate into Th2 cells. These cells
release numerous cytokines IL-4, IL-5, IL-8 & IL-13.
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early asthmatic response contributes to .....ANSWER..... increased
bronchial hyperresponsiveness, fibroblast proliferation, epithelial
injury, and airway scaring
What happens during an early asthmatic response
.....ANSWER..... IgE causes mast cell degranulation, causing
vasodilation, increased capillary permeability, mucosal edema,
bronchial smooth muscle contraction (bronchospasm), and
tenacious mucus secretion
Late asthmatic response .....ANSWER..... Begins 4-8 hours after
early response; synthesis of leukotrienes contributes to prolonged
smooth muscle contraction, eosinophil mediators cause direct
tissue injury with fibroblast proliferation and airway scaring
Airway remodeling .....ANSWER..... Untreated inflammation which
can lead to long-term airway damage that is irreversible.
Bronchiolitis .....ANSWER..... inflammation of the bronchioles
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chronic bronchitis .....ANSWER..... rapid respiratory rate,
accessory muscle use, low-grade fever, dry nonproductive cough,
hyperinflated chest
Bronchiolitis obliterans .....ANSWER..... late-stage fibrotic process
that occludes the airways and causes permanent scarring of the
lungs
Bronchitis can cause respiratory acidosis. How? .....ANSWER.....
With alveolar hypoventilation. Carbon dioxide is retained,
increasing H+ (as HCO3) and producing acidosis.
hypercapnia .....ANSWER..... excessive carbon dioxide in the
blood
Perfusion:related to asthma .....ANSWER..... prolonged
hypoxemia and inadequate tissue oxygenation activates
anaerobic glycolysis, producing lactic acid and resulting in
metabolic acidosis
NR507 MID-TERM EXAM (CHAMBERLAIN) NEWEST
2025 ACTUAL EXAM| NR507 ADVANCED
PATHOPHYSIOLOGY MID-TERM EXAM WITH 200 REAL
EXAM QUESTIONS AND CORRECT DETAILED ANSWERS
(VERIFIED ANSWERS) ALREADY GRADED A+ (BRAND
NEW!!)
Asthma .....ANSWER..... A chronic allergic disorder characterized
by episodes of severe breathing difficulty, coughing, and
wheezing.
What is constricted in asthma? .....ANSWER..... Bronchi
Early asthmatic response .....ANSWER..... Antigen exposure to
bronchial mucosa activates dendritic cells to present the antigen
to CD4+ Tcells, which differentiate into Th2 cells. These cells
release numerous cytokines IL-4, IL-5, IL-8 & IL-13.
,Page 2 of 24
early asthmatic response contributes to .....ANSWER..... increased
bronchial hyperresponsiveness, fibroblast proliferation, epithelial
injury, and airway scaring
What happens during an early asthmatic response
.....ANSWER..... IgE causes mast cell degranulation, causing
vasodilation, increased capillary permeability, mucosal edema,
bronchial smooth muscle contraction (bronchospasm), and
tenacious mucus secretion
Late asthmatic response .....ANSWER..... Begins 4-8 hours after
early response; synthesis of leukotrienes contributes to prolonged
smooth muscle contraction, eosinophil mediators cause direct
tissue injury with fibroblast proliferation and airway scaring
Airway remodeling .....ANSWER..... Untreated inflammation which
can lead to long-term airway damage that is irreversible.
Bronchiolitis .....ANSWER..... inflammation of the bronchioles
, Page 3 of 24
chronic bronchitis .....ANSWER..... rapid respiratory rate,
accessory muscle use, low-grade fever, dry nonproductive cough,
hyperinflated chest
Bronchiolitis obliterans .....ANSWER..... late-stage fibrotic process
that occludes the airways and causes permanent scarring of the
lungs
Bronchitis can cause respiratory acidosis. How? .....ANSWER.....
With alveolar hypoventilation. Carbon dioxide is retained,
increasing H+ (as HCO3) and producing acidosis.
hypercapnia .....ANSWER..... excessive carbon dioxide in the
blood
Perfusion:related to asthma .....ANSWER..... prolonged
hypoxemia and inadequate tissue oxygenation activates
anaerobic glycolysis, producing lactic acid and resulting in
metabolic acidosis
