PHARMACOLOGY TEST BANK
QUESTIONS AND ANSWERS
Which bdrugs bwill bgo bthrough ba bpharmaceutic bphase bafter bit bis badministered?
a. bIntramuscular bcephalosporins
b. bIntravenous bvasopressors
c. bOral banalgesics
d. bSubcutaneous bantiglycemics b- bcorrect banswer✔✔c
The bnurse bis bpreparing bto badminister ban boral bmedication band bwants bto bensure ba
brapid bdrug baction. bWhich bform bof bthe bmedication bwill bthe bnurse badminister?
a. bCapsule
b. bEnteric-coated bpill
c. bLiquid bsuspension
d. bTablet b- bcorrect banswer✔✔c
The bnurse bis bteaching ba bpatient bwho bwill bbe bdischarged bhome bwith ba bprescription
bfor ban benteric-coated btablet. bWhich bstatement bby bthe bpatient bindicates
bunderstanding bof bthe bteaching?
a. b"I bmay bcrush bthe btablet band bput bit bin bapplesauce bto bimprove babsorption."
b. b"I bshould bconsume bacidic bfoods bto benhance babsorption bof bthis bmedication."
c. b"I bshould bexpect ba bdelay bin bonset bof bthe bdrug's beffects bafter btaking bthe btablet."
d. b"I bshould btake bthis bmedication bwith bhigh-fat bfoods bto bimprove bits baction." b-
bcorrect banswer✔✔c
A bpatient bwho bis bnewly bdiagnosed bwith btype b1 bdiabetes bmellitus basks bwhy binsulin
bmust bbe bgiven bby bsubcutaneous binjection binstead bof bby bmouth. bThe bnurse bwill
bexplain bthat bthis bis bbecause
a. babsorption bis bdiminished bby bthe bfirst-pass beffects bin bthe bliver.
b. babsorption bis bfaster bwhen binsulin bis bgiven bsubcutaneously.
c. bdigestive benzymes bin bthe bgastrointestinal btract bprevent babsorption.
d. bthe boral bform bis bless bpredictable bwith bmore badverse beffects. b- bcorrect
banswer✔✔c
The bnurse bis bpreparing bto badminister ban boral bmedication bthat bis bwater-soluble.
bThe bnurse bunderstands bthat bthis bdrug
a. bmust bbe btaken bon ban bempty bstomach.
b. brequires bactive btransport bfor babsorption.
,c. bshould bbe btaken bwith bfatty bfoods.
d. bwill breadily bdiffuse binto bthe bgastrointestinal btract. b- bcorrect banswer✔✔b
A bnurse bis bpreparing bto badminister ban boral bdrug bthat bis bbest babsorbed bin ban
bacidic benvironment. bHow bwill bthe bnurse bgive bthe bdrug?
a. bOn ban bempty bstomach
b. bWith ba bfull bglass bof bwater
c. bWith bfood
d. bWith bhigh-fat bfood b- bcorrect banswer✔✔c
The bnurse bis bpreparing ban binjectable bdrug band bwants bto badminister bit bfor brapid
babsorption. bHow bwill bthe bnurse bgive bthis bmedication?
a. bIM binto bthe bdeltoid bmuscle
b. bIM binto bthe bgluteal bmuscle
c. bSubQ binto babdominal btissue
d. bSubQ binto bthe bupper barm b- bcorrect banswer✔✔a
The bnurse bis breviewing bmedication binformation bwith ba bnursing bstudent bprior bto
badministering ban boral bdrug band bnotes bthat bthe bdrug bhas bextensive bfirst-pass
beffects. bWhich bstatement bby bthe bstudent bindicates ba bneed bfor bfurther bteaching
babout bthis bmedication?
a. b"The bfirst-pass beffect bmeans bthe bdrug bmay bbe babsorbed binto bsystemic
bcirculation bfrom bthe bintestinal blumen."
b. b"The bfirst-pass beffect bmeans bthe bdrug bmay bbe bchanged bto ban binactive bform
band bexcreted."
c. b"The bfirst-pass beffect bmeans bthe bdrug bmay bbe bchanged bto ba bmetabolite, bwhich
bmay bbe bmore bactive bthan bthe boriginal."
d. b"The bfirst-pass beffect bmeans bthe bdrug bmay bbe bunchanged bas bit bpasses
bthrough bthe bliver." b- bcorrect banswer✔✔a
The bnurse bprepares bto bchange ba bpatient's bmedication bfrom ban bintravenous bto ban
boral bform band bnotes bthat bthe boral bform bis bordered bin ba bhigher bdose. bThe bnurse
bunderstands bthat bthis bis bdue bto bdifferences bin
a. bbioavailability.
b. bpinocytosis.
c. bprotein bbinding.
d. btachyphylaxis. b- bcorrect banswer✔✔a
The bnurse bis bpreparing bto badminister ba bdrug band blearns bthat bit bbinds bto bprotein
bat ba brate bof b90%. bThe bpatient's bserum balbumin blevel bis blow. bThe bnurse bwill
bobserve bthe bpatient bfor
a. bdecreased bdrug babsorption.
b. bdecreased bdrug binteractions.
c. bdecreased bdrug btoxicity.
d. bincreased bdrug beffects. b- bcorrect banswer✔✔d
, The bnurse bis badministering btwo bdrugs bto ba bpatient band blearns bthat bboth bdrugs
bare bhighly bprotein-bound. bThe bnurse bmay bexpect
a. bdecreased bbioavailability bof bboth bdrugs.
b. bdecreased bdrug beffects.
c. bdecreased bdrug binteractions.
d. bincreased brisk bof badverse beffects. b- bcorrect banswer✔✔d
The bnurse bgives ba bmedication bto ba bpatient bwith ba bhistory bof bliver bdisease. bThe
bnurse bwill bmonitor bthis bpatient bfor
a. bdecreased bdrug beffects.
b. bincreased bdrug beffects.
c. bdecreased btherapeutic brange.
d. bincreased btherapeutic brange. b- bcorrect banswer✔✔b
The bnurse bgives b800 bmg bof ba bdrug bthat bhas ba bhalf-life bof b8 bhours. bHow bmuch
bdrug bwill bbe bleft bin bthe bbody bin b24 bhours bif bno badditional bdrug bis bgiven?
a. bNone
b. b50 bmg
c. b100 bmg
d. b200 bmg b- bcorrect banswer✔✔c
If ba bdrug bhas ba bhalf-life bof b12 bhours band bis bgiven btwice bdaily bstarting bat b0800
bon ba bMonday, bwhen bwill ba bsteady bstate bbe bachieved?
a. b0800 bon bTuesday
b. b0800 bon bWednesday
c. b0800 bon bThursday
d. b0800 bon bFriday b- bcorrect banswer✔✔b
The bnurse badministers balbuterol bto ba bpatient bwho bhas basthma. bThe balbuterol bacts
bby bstimulating bbeta2-adrenergic breceptors bto bcause bbronchodilation. bThe bnurse
bunderstands bthat balbuterol bis ba bbeta-adrenergic
a. bagonist.
b. bantagonist.
c. binhibitor.
d. bdepressant. b- bcorrect banswer✔✔a
The bnurse bis bexplaining bto bthe bpatient bwhy ba bnonspecific bdrug bhas bso bmany bside
beffects. bWhich bstatement bby bthe bpatient bindicates ba bneed bfor bfurther bteaching?
a. b"Nonspecific bdrugs bcan baffect bspecific breceptor btypes bin bdifferent bbody btissues."
b. b"Nonspecific bdrugs bcan baffect ba bvariety bof breceptor btypes bin bsimilar bbody
btissues."
c. b"Nonspecific bdrugs bcan baffect bhormone bsecretion bas bwell bas bcellular bfunctions."
d. b"Nonspecific bdrugs brequire bhigher bdoses bthan bspecific bdrugs bto bbe beffective." b-
bcorrect banswer✔✔d
QUESTIONS AND ANSWERS
Which bdrugs bwill bgo bthrough ba bpharmaceutic bphase bafter bit bis badministered?
a. bIntramuscular bcephalosporins
b. bIntravenous bvasopressors
c. bOral banalgesics
d. bSubcutaneous bantiglycemics b- bcorrect banswer✔✔c
The bnurse bis bpreparing bto badminister ban boral bmedication band bwants bto bensure ba
brapid bdrug baction. bWhich bform bof bthe bmedication bwill bthe bnurse badminister?
a. bCapsule
b. bEnteric-coated bpill
c. bLiquid bsuspension
d. bTablet b- bcorrect banswer✔✔c
The bnurse bis bteaching ba bpatient bwho bwill bbe bdischarged bhome bwith ba bprescription
bfor ban benteric-coated btablet. bWhich bstatement bby bthe bpatient bindicates
bunderstanding bof bthe bteaching?
a. b"I bmay bcrush bthe btablet band bput bit bin bapplesauce bto bimprove babsorption."
b. b"I bshould bconsume bacidic bfoods bto benhance babsorption bof bthis bmedication."
c. b"I bshould bexpect ba bdelay bin bonset bof bthe bdrug's beffects bafter btaking bthe btablet."
d. b"I bshould btake bthis bmedication bwith bhigh-fat bfoods bto bimprove bits baction." b-
bcorrect banswer✔✔c
A bpatient bwho bis bnewly bdiagnosed bwith btype b1 bdiabetes bmellitus basks bwhy binsulin
bmust bbe bgiven bby bsubcutaneous binjection binstead bof bby bmouth. bThe bnurse bwill
bexplain bthat bthis bis bbecause
a. babsorption bis bdiminished bby bthe bfirst-pass beffects bin bthe bliver.
b. babsorption bis bfaster bwhen binsulin bis bgiven bsubcutaneously.
c. bdigestive benzymes bin bthe bgastrointestinal btract bprevent babsorption.
d. bthe boral bform bis bless bpredictable bwith bmore badverse beffects. b- bcorrect
banswer✔✔c
The bnurse bis bpreparing bto badminister ban boral bmedication bthat bis bwater-soluble.
bThe bnurse bunderstands bthat bthis bdrug
a. bmust bbe btaken bon ban bempty bstomach.
b. brequires bactive btransport bfor babsorption.
,c. bshould bbe btaken bwith bfatty bfoods.
d. bwill breadily bdiffuse binto bthe bgastrointestinal btract. b- bcorrect banswer✔✔b
A bnurse bis bpreparing bto badminister ban boral bdrug bthat bis bbest babsorbed bin ban
bacidic benvironment. bHow bwill bthe bnurse bgive bthe bdrug?
a. bOn ban bempty bstomach
b. bWith ba bfull bglass bof bwater
c. bWith bfood
d. bWith bhigh-fat bfood b- bcorrect banswer✔✔c
The bnurse bis bpreparing ban binjectable bdrug band bwants bto badminister bit bfor brapid
babsorption. bHow bwill bthe bnurse bgive bthis bmedication?
a. bIM binto bthe bdeltoid bmuscle
b. bIM binto bthe bgluteal bmuscle
c. bSubQ binto babdominal btissue
d. bSubQ binto bthe bupper barm b- bcorrect banswer✔✔a
The bnurse bis breviewing bmedication binformation bwith ba bnursing bstudent bprior bto
badministering ban boral bdrug band bnotes bthat bthe bdrug bhas bextensive bfirst-pass
beffects. bWhich bstatement bby bthe bstudent bindicates ba bneed bfor bfurther bteaching
babout bthis bmedication?
a. b"The bfirst-pass beffect bmeans bthe bdrug bmay bbe babsorbed binto bsystemic
bcirculation bfrom bthe bintestinal blumen."
b. b"The bfirst-pass beffect bmeans bthe bdrug bmay bbe bchanged bto ban binactive bform
band bexcreted."
c. b"The bfirst-pass beffect bmeans bthe bdrug bmay bbe bchanged bto ba bmetabolite, bwhich
bmay bbe bmore bactive bthan bthe boriginal."
d. b"The bfirst-pass beffect bmeans bthe bdrug bmay bbe bunchanged bas bit bpasses
bthrough bthe bliver." b- bcorrect banswer✔✔a
The bnurse bprepares bto bchange ba bpatient's bmedication bfrom ban bintravenous bto ban
boral bform band bnotes bthat bthe boral bform bis bordered bin ba bhigher bdose. bThe bnurse
bunderstands bthat bthis bis bdue bto bdifferences bin
a. bbioavailability.
b. bpinocytosis.
c. bprotein bbinding.
d. btachyphylaxis. b- bcorrect banswer✔✔a
The bnurse bis bpreparing bto badminister ba bdrug band blearns bthat bit bbinds bto bprotein
bat ba brate bof b90%. bThe bpatient's bserum balbumin blevel bis blow. bThe bnurse bwill
bobserve bthe bpatient bfor
a. bdecreased bdrug babsorption.
b. bdecreased bdrug binteractions.
c. bdecreased bdrug btoxicity.
d. bincreased bdrug beffects. b- bcorrect banswer✔✔d
, The bnurse bis badministering btwo bdrugs bto ba bpatient band blearns bthat bboth bdrugs
bare bhighly bprotein-bound. bThe bnurse bmay bexpect
a. bdecreased bbioavailability bof bboth bdrugs.
b. bdecreased bdrug beffects.
c. bdecreased bdrug binteractions.
d. bincreased brisk bof badverse beffects. b- bcorrect banswer✔✔d
The bnurse bgives ba bmedication bto ba bpatient bwith ba bhistory bof bliver bdisease. bThe
bnurse bwill bmonitor bthis bpatient bfor
a. bdecreased bdrug beffects.
b. bincreased bdrug beffects.
c. bdecreased btherapeutic brange.
d. bincreased btherapeutic brange. b- bcorrect banswer✔✔b
The bnurse bgives b800 bmg bof ba bdrug bthat bhas ba bhalf-life bof b8 bhours. bHow bmuch
bdrug bwill bbe bleft bin bthe bbody bin b24 bhours bif bno badditional bdrug bis bgiven?
a. bNone
b. b50 bmg
c. b100 bmg
d. b200 bmg b- bcorrect banswer✔✔c
If ba bdrug bhas ba bhalf-life bof b12 bhours band bis bgiven btwice bdaily bstarting bat b0800
bon ba bMonday, bwhen bwill ba bsteady bstate bbe bachieved?
a. b0800 bon bTuesday
b. b0800 bon bWednesday
c. b0800 bon bThursday
d. b0800 bon bFriday b- bcorrect banswer✔✔b
The bnurse badministers balbuterol bto ba bpatient bwho bhas basthma. bThe balbuterol bacts
bby bstimulating bbeta2-adrenergic breceptors bto bcause bbronchodilation. bThe bnurse
bunderstands bthat balbuterol bis ba bbeta-adrenergic
a. bagonist.
b. bantagonist.
c. binhibitor.
d. bdepressant. b- bcorrect banswer✔✔a
The bnurse bis bexplaining bto bthe bpatient bwhy ba bnonspecific bdrug bhas bso bmany bside
beffects. bWhich bstatement bby bthe bpatient bindicates ba bneed bfor bfurther bteaching?
a. b"Nonspecific bdrugs bcan baffect bspecific breceptor btypes bin bdifferent bbody btissues."
b. b"Nonspecific bdrugs bcan baffect ba bvariety bof breceptor btypes bin bsimilar bbody
btissues."
c. b"Nonspecific bdrugs bcan baffect bhormone bsecretion bas bwell bas bcellular bfunctions."
d. b"Nonspecific bdrugs brequire bhigher bdoses bthan bspecific bdrugs bto bbe beffective." b-
bcorrect banswer✔✔d
