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AANP Exam – New Updated Version | Complete Study Guide, Practice Questions & Correct Answers (Latest 2025 Edition)

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This AANP Exam study guide provides the most recent, updated content for Nurse Practitioner students preparing for certification. Includes high-yield practice questions, correct answers, and detailed rationales covering primary care, diagnostics, pharmacology, and clinical decision-making. Perfect for FNP, AGNP, and other NP specialty students looking to maximize test scores and clinical readiness.

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AANP Exam (NEW UPDATED VERSION) LATEST ACTUAL EXAM QUESTIONS AND
CORRECT ANSWERS (VERIFIED QUESTIONS AND ANSWERS) | GUARANTEED PASS
A+ [2026]




Erythropoetin - CORRECT ANSWER ✔✔✔✔✔ 90 % renal, 10% hepatic, need
supplementation when GFR is less than 49

Reticulocytes - CORRECT ANSWER ✔✔✔✔✔ In health, make up 1-2 % of total
RBCs, increased in response to anema. Absence of reticulocytosis or presence of
reticulocytopenia shows inadequate bone marrow response.

Hemoglobin - CORRECT ANSWER ✔✔✔✔✔ normal is 12 for females and 15 for
males. Ratio to hematocrit is 1:3

MCV - CORRECT ANSWER ✔✔✔✔✔ determines red blood cell size - normal is
80-96

MCH - CORRECT ANSWER ✔✔✔✔✔ reflects hgb content and color, normal is
31-37

,RDW - CORRECT ANSWER ✔✔✔✔✔ variation of RBC size - normal is 11.5-15%

Normocytic, normochromic , normal RDW - CORRECT ANSWER ✔✔✔✔✔ acute
blood loss, anemia of chronic disease

Microcytic, hypochromic anemia, elevated RDW - CORRECT ANSWER ✔✔✔✔✔
Iron deficiency anemia

Microcytic, hypochromic, normal RDW - CORRECT ANSWER ✔✔✔✔✔ alpha or
beta thalassemia minor

Macrocytic, normochromic, elevated RDW - CORRECT ANSWER ✔✔✔✔✔
Vitamin B12 deficiency, folate deficiency, pernicious anemia

Macrocytosis without anemia - CORRECT ANSWER ✔✔✔✔✔ use of
medications like tegretol, AZT, depakote, dilantin, alcohol

Heart murmur seen in b12 deficiency - CORRECT ANSWER ✔✔✔✔✔ Hemic
murmur

Most common pathogen in CAP, ABRS, AOM - CORRECT ANSWER ✔✔✔✔✔ S.
pneumoniae

Common pathogen in ABRS, AOM, CAP particularly with recurrent infections and
tobacco use - CORRECT ANSWER ✔✔✔✔✔ H. influenzae, more than 30% now
pcn resistant via beta lactamase production

First line treatment for Acute Bacterial Rhinosinusitis - CORRECT ANSWER
✔✔✔✔✔ Augmentin 500/125 TID or 875/125 BID

Second line treatment for Acute Bacterial Rhinosinusitis - CORRECT ANSWER
✔✔✔✔✔ Augmentin 2000/125 BID or doxy 100 mg BID or 200 mg QD

Treatment for ABRS if allergic to PCN, Cephalosporins - CORRECT ANSWER
✔✔✔✔✔ Doxy, Levofloxacin, Moxifloxacin

,Treatment for ABRS if antibiotic resistance of failed initial therapy - CORRECT
ANSWER ✔✔✔✔✔ Doxy, levofloxacin, moxifloxacin

Presbycusis - CORRECT ANSWER ✔✔✔✔✔ slowly progressive hearing loss that
is symmetric and high frequency

1st line controller therapy in allergic rhinitis - CORRECT ANSWER ✔✔✔✔✔
Intranasal corticosteriods like Flonase, Nasonex, Nasacort, Omnaris. Side effects
are that nasal irritation and bleeding may occur. Optimal efficacy may take 1-2
weeks.

1st line rescue treatment in allergic rhinitis - CORRECT ANSWER ✔✔✔✔✔
Nasal antihistamines, esp if there is nasal congestion. sedation could occur.
Drugs like astelin, Astepro, and patanase

1st generation oral antihistamines - CORRECT ANSWER ✔✔✔✔✔ significant
potential to cause sedation and anticholinergic effects so not a first line therapy.
Ex. benadryl, chlor trimeton, dimetapp, vistaril.

2nd generation oral antihistamines - CORRECT ANSWER ✔✔✔✔✔ These are
preferred over because no anticholinergic effects but not as helpful with nasal
congestion. Ex. claritin, clarinex, zyrtec, allergra

Oral decongestants - CORRECT ANSWER ✔✔✔✔✔ alpha adrenergic agonist so
vasoconstrictive. Take caution with the elderly, young children, HTN, bladder
neck obstruction, glaucoma, and hyperthyroidism. Ex. sudafed

Nasal decongestants - CORRECT ANSWER ✔✔✔✔✔ Alpha adrenergic agonist
so vasoconstrictive. Can cause rebound congestion/medicamentosa so limit use
to 5-7 days.

Intranasal anticholinergics - CORRECT ANSWER ✔✔✔✔✔ reduce runny nose
because of drying action. No effect on other nasal symptoms. Dryness can occur.
Ex.. Atrovent

, Found on fundoscopic exam of person with angle-closure glaucoma - CORRECT
ANSWER ✔✔✔✔✔ deeply cupped optic disc because of increase intraocular
pressure than pushes the optic disc backwards., acute, painful

Amsler grid - CORRECT ANSWER ✔✔✔✔✔ screening test for macular
problems.

Tonometry - CORRECT ANSWER ✔✔✔✔✔ measurement of intraoccular
pressure, screen for glaucoma

Presbyopia - CORRECT ANSWER ✔✔✔✔✔ Hardening of the lens, close vision
problems, adults over 45

Senile cataracts - CORRECT ANSWER ✔✔✔✔✔ lens clouding, progressive
vision dimming, distance vision problems, close vision usually retained and
often improves. Risk factors are tobacco use, poor nutrition, sun exposure,
systemic corticosteriod therapy. Potentially correctable with surgery.

Open-angle glaucoma - CORRECT ANSWER ✔✔✔✔✔ Painless, gradual onset of
increased intraocular pressure leading to optic atrophy. Causes a loss of
peripheral vision if not treated. Avoidable with appropriate and ongoing
intervention. more than 80% of all glaucoma. Treat with topical miotics, beta
blockers, or surgery

Angle closure glaucoma - CORRECT ANSWER ✔✔✔✔✔ sudden increases in
intraocular pressure. Usually unilateral, painful, red eye, halos around lights,
eyeball firm when compare to other. Immediate referral to opthmalogy

Macular degeneration - CORRECT ANSWER ✔✔✔✔✔ thickening sclerotic
changes in retinal basement membrane complex. Causes painless changes in
vision including distortion of central vision. On fundo exam will see drusen (soft
yellow deposits in macular region). Risk factors are tobacco use, sun exposure.
No treatment available for dry form. Laser treatment or intraviteal injection of
antivascular growth factor for wet form
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