NUR 651 Final Study Guide
Comprehensive Questions with
Verified Answers Graded A+
Clinical judgement in prescribing includes: - Answer: Factoring in the cost to the patient of the
medication prescribed
The route of excretion of a volatile drug will likely be the: - Answer: lungs
The NP chooses to give cephalexin every 8 hours based on knowledge of the drugs: - Answer:
biological half-life
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
1. When the drug has a wide therapeutic range
2. When the drug will be administered for a short time only
3. When there is a high correlation between the dose and saturation of receptor sites
4. To determine if a drug is in the therapeutic range - Answer: To determine if the drug is in the
therapeutic range
Drugs that use CYP 3A4 isoenzymes for metabolism may:
,1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 - Answer: Both 1 & 2: induce OR inhibit metabolism of another drug
The prudent NP would prescribe liquid ibuprofen for a 6-year-old because: - Answer: The 6-year-
old may not be able to swallow pills
In deciding which drug to prescribe of all multiple drugs used to treat a condition, the NP
chooses drug A because: - Answer: It will be taken twice daily at home
Your patient asks the difference in drug effects between men and women. What should the NP
know about the differences between pharmacokinetics of men and women? - Answer:
Percentage of fat differs between genders
Drugs that have a significant first-pass effect: - Answer: Are rapidly metabolized by the liver and
may have little if any desired action
Azithromycin dosing requires the first days dosage be twice those of the other 4 days of the
prescription. This is considered a loading dose. Loading doses: - Answer: Rapidly achieve drug
levels in the theraputic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the: - Answer: onset of action
Drugs that are receptor agonists may demonstrate what property? - Answer: Describes the
extent of effect (response) produced by a given drug concentration (dose)
Shows the relationship between the dosage/concentration and the effect of the drug
concentration
, Therapeutic window (range) - Answer: The range of plasma drug concentration with high
probability of therapeutic response
Provides a fixed comparison for drug safety
What is a narrow therapeutic window? - Answer: A drug that has little difference between
therapeutic and toxic doses
Treatment goals in prescribing should be: - Answer: Patient centered
storage reservoirs: - Answer: Fat and tissue that the drug has been distributed to
Passive monitoring: - Answer: patient is educated on expected outcome and instructed to
contact provider (expected side effects)
A potentially life-threatening adverse response to ACE inhibitors is angioedema. Which
statement is true about this adverse response? - Answer: Swelling of the tongue and hoarseness
are the most common sympotms.
ACE inhibitors are the drug of choice in treating hypertension in diabetic patients because: -
Answer: They improve insulin sensitivity
Improve renal hemodynamics
Reduce the production of angiotensin II
Ray has been diagnosed with hypertension and an ACE inhibitor is determined to be needed.
Prior to prescribing this drug, the NP should assess for:
A. Hypokalemia
Comprehensive Questions with
Verified Answers Graded A+
Clinical judgement in prescribing includes: - Answer: Factoring in the cost to the patient of the
medication prescribed
The route of excretion of a volatile drug will likely be the: - Answer: lungs
The NP chooses to give cephalexin every 8 hours based on knowledge of the drugs: - Answer:
biological half-life
Phenytoin requires that a trough level be drawn. Peak and trough levels are done:
1. When the drug has a wide therapeutic range
2. When the drug will be administered for a short time only
3. When there is a high correlation between the dose and saturation of receptor sites
4. To determine if a drug is in the therapeutic range - Answer: To determine if the drug is in the
therapeutic range
Drugs that use CYP 3A4 isoenzymes for metabolism may:
,1. Induce the metabolism of another drug
2. Inhibit the metabolism of another drug
3. Both 1 and 2
4. Neither 1 nor 2 - Answer: Both 1 & 2: induce OR inhibit metabolism of another drug
The prudent NP would prescribe liquid ibuprofen for a 6-year-old because: - Answer: The 6-year-
old may not be able to swallow pills
In deciding which drug to prescribe of all multiple drugs used to treat a condition, the NP
chooses drug A because: - Answer: It will be taken twice daily at home
Your patient asks the difference in drug effects between men and women. What should the NP
know about the differences between pharmacokinetics of men and women? - Answer:
Percentage of fat differs between genders
Drugs that have a significant first-pass effect: - Answer: Are rapidly metabolized by the liver and
may have little if any desired action
Azithromycin dosing requires the first days dosage be twice those of the other 4 days of the
prescription. This is considered a loading dose. Loading doses: - Answer: Rapidly achieve drug
levels in the theraputic range
The point in time on the drug concentration curve that indicates the first sign of a therapeutic
effect is the: - Answer: onset of action
Drugs that are receptor agonists may demonstrate what property? - Answer: Describes the
extent of effect (response) produced by a given drug concentration (dose)
Shows the relationship between the dosage/concentration and the effect of the drug
concentration
, Therapeutic window (range) - Answer: The range of plasma drug concentration with high
probability of therapeutic response
Provides a fixed comparison for drug safety
What is a narrow therapeutic window? - Answer: A drug that has little difference between
therapeutic and toxic doses
Treatment goals in prescribing should be: - Answer: Patient centered
storage reservoirs: - Answer: Fat and tissue that the drug has been distributed to
Passive monitoring: - Answer: patient is educated on expected outcome and instructed to
contact provider (expected side effects)
A potentially life-threatening adverse response to ACE inhibitors is angioedema. Which
statement is true about this adverse response? - Answer: Swelling of the tongue and hoarseness
are the most common sympotms.
ACE inhibitors are the drug of choice in treating hypertension in diabetic patients because: -
Answer: They improve insulin sensitivity
Improve renal hemodynamics
Reduce the production of angiotensin II
Ray has been diagnosed with hypertension and an ACE inhibitor is determined to be needed.
Prior to prescribing this drug, the NP should assess for:
A. Hypokalemia
