NR 293 Exam 2 Study Guide 2025: Pharmacology for Nursing Practice Questions & Review

Page 1 of 60


NR293 / NR-293 EXAM 2 (LATEST UPDATE 2025):

PHARMACOLOGY FOR NURSING PRACTICE |

COMPLETE GUIDE WITH QUESTIONS AND VERIFIED

ANSWERS | 100% CORRECT - CHAMBERLAIN

What are antihistamines? .....ANSWER.....histamine antagonists

Antihistamines MOA .....ANSWER.....dry up secretions; blocks H1

receptors

Antihistamines Indications .....ANSWER.....allergic rhinitis (r/t hay

fever, mold, dust); mild allergic reactions/ anaphylaxis;

angioedema, pruritis, urticaria

Antihistamines can also be used to treat... .....ANSWER.....motion

sickness, Parkinson's, vertigo

Antihistamines Adverse Effects .....ANSWER.....anticholinergic

effects: dry mouth, urinary retention, constipation, vision changes;

drowsiness, dizziness

,Page 2 of 60


Antihistamines contraindiactions .....ANSWER.....allergy, narrow-

angle glaucoma, acute asthma attacks, lower respiratory

diseases, cardiac disease, HTN, BPH (due to potential for urinary

retention), risk for falls & injuries r/t sedation

Antihistamines client teaching .....ANSWER.....best taken w/food,

avoid taking w/CNS depressant and ETOH, drink water/mouth

care/chew gum/eat candy for dry mouth

1st generation (Tradtional) Antihistamine example

.....ANSWER.....diphenhydramine (benadryl)

1st generation (Tradtional) Antihistamine MOA

.....ANSWER.....works peripherally and centrally in the CNS

1st generation (Tradtional) Antihistamine adverse effects

.....ANSWER.....increases sedation, dizziness, anticholinergic

effects

2nd generation (Non-sedating) Antihistamine examples

.....ANSWER.....Loratadine (claratin) and fexofenadine (allegra)

,Page 3 of 60


Age range for loratadine .....ANSWER.....not for children under 2

r/o seizures

2nd generation (Non-sedating) Antihistamine MOA

.....ANSWER.....works peripherally to block the actions of

histamine; longer duration of action (increased compliance)

2nd generation (Non-sedating) Antihistamine adverse effects

.....ANSWER.....fewer CNS effects and anticholinergic effects

Decongestants MOA .....ANSWER.....decrease secretions

Different classes of Decongestants .....ANSWER.....adrenergic

decongestants, anticholinergics, corticosteriods

Adrenergic decongestants examples

.....ANSWER.....pseudoephedrine (sudafed) and oxymetazoline

(afrin)

, Page 4 of 60


Adrenergic decongestants and Anticholinergics Indications

.....ANSWER.....nasal congestion r/t acute/chronic rhinitis, colds,

sinusitis, hay fever, allergies

Anticholinergics examples .....ANSWER.....Ipratropium and

tiotropium

Adrenergic decongestants contraindications

.....ANSWER.....narrow angle glaucoma, uncontrolled CV

disease/HTN, DM, hyperthyroidism

Adrenergic decongestants adverse effects .....ANSWER.....SNS

stimulation, palpations, insomnia, nervousness, tremors

Adrenergic decongestants nursing considerations

.....ANSWER.....monitor HR/BP; oxymetazoline: powerful topical

intranasal, use no longer than 3d = rebound congestion;

pseudoephedrine: oral

Anticholinergics contraindications .....ANSWER.....narrow angle

glaucoma, urinary retention, BPH