Hematology Intern Exam 3 Questions with
Answers (100% Correct Answers)
What coag factors Consume in clot and not found in serum? Answer: I, II, V,
VIII and XIII
What coag factors are vitamin K dependant, Removed by absorption with
barium sulfate, and affected by coumadin? Answer: II, VII, IX, X
What coag Factors are contact factors? Answer: XII, XI, Fletcher and
Fitzgerald
What Coag Factors are Labile? Answer: V, VIII
What Coag Factor is a comon path factor, Normal PT, Increase PTT and is
Hemophilia B (Christmas Dz)? Answer: Factoer IX deficiency
What coag factor has a normal PT, Normal PTT, Measure with urea solubility,
Treat with cryoprecipitate? Answer: Factor XIII Deficiency
What coag factor has a Normal PT, Increase PTT, Causes thrombosis not
bleeding? Answer: Factor XII deficiency
What coag factor has increase PT and PTT, Measured by Thrombin Time,
Treat with cryoprecipitate? Answer: Factor I deficiency
What coag Factor has increase PT and normal PTT? Answer: Factor VII
deficiency
What coag factor has increase PT and PTT? Answer: Factor X deficiency
Why does liver dz cause bleeding? Answer: Most plasma coag factors are
produced in the liver so if the liver is dzed, production is reduced. If the
concentration of factors is reduced, the coag test will be prolonged.
What factor is normal or elevated in liver dz? Answer: Factor VIII is partly
produced by vessel endothelial cells so it is normal or increased in liver dz.
, 2
What is the purpose of the trypsin inhibitor in FSP or FDP slide agglutination
test? Answer: Trypsin is an antifibrinolytic agent so it prevents invitro
fibrinolysis, allowing the test to detect only the fibrinolysis that occurred in the
pt prior to the blood collection.
What is the diagnosis if a patient has a + FSP and negative D-Dimer? Answer:
Primary or pathologic fibrinogenolysis
What is the diagnosis if a patient has a + FSP and + D-Dimer? Answer: DIC or
thrombosis
List the factors in the extrinsic system? Answer: III and VII
List the factors in the intrinsic system? Answer: XII, XI, IX, VIII
What is the therapeutic range for INR? Answer: 2.0-3.0 for most patients on
coumadin
What are the reagents used in the PT? Answer: Rabbit thromboplastin
Calcium in the thromboplastin
What are the reagents used in the PTT Answer: Activated partial
thromboplastin (Actin)
Calcium Chloride
what is the purpose of Rabit Thromboplastin in PT? Answer: Acts as tissue
factor III to activate factor VII to start the extrinstic system.
what is the purpose of Calcium in the thromboplastin in PT? Answer: adds
back the calcium bound by the sodium citrate anticoagulant in the collection
tube.
What is the purpose of Activated partial thromboplastin (Actin) in PTT?
Answer: contains a commercial phospholipid and a negatively charge particle
like kaolin or ellagic acid to activate Factor XII to start the intrinsic system.
Answers (100% Correct Answers)
What coag factors Consume in clot and not found in serum? Answer: I, II, V,
VIII and XIII
What coag factors are vitamin K dependant, Removed by absorption with
barium sulfate, and affected by coumadin? Answer: II, VII, IX, X
What coag Factors are contact factors? Answer: XII, XI, Fletcher and
Fitzgerald
What Coag Factors are Labile? Answer: V, VIII
What Coag Factor is a comon path factor, Normal PT, Increase PTT and is
Hemophilia B (Christmas Dz)? Answer: Factoer IX deficiency
What coag factor has a normal PT, Normal PTT, Measure with urea solubility,
Treat with cryoprecipitate? Answer: Factor XIII Deficiency
What coag factor has a Normal PT, Increase PTT, Causes thrombosis not
bleeding? Answer: Factor XII deficiency
What coag factor has increase PT and PTT, Measured by Thrombin Time,
Treat with cryoprecipitate? Answer: Factor I deficiency
What coag Factor has increase PT and normal PTT? Answer: Factor VII
deficiency
What coag factor has increase PT and PTT? Answer: Factor X deficiency
Why does liver dz cause bleeding? Answer: Most plasma coag factors are
produced in the liver so if the liver is dzed, production is reduced. If the
concentration of factors is reduced, the coag test will be prolonged.
What factor is normal or elevated in liver dz? Answer: Factor VIII is partly
produced by vessel endothelial cells so it is normal or increased in liver dz.
, 2
What is the purpose of the trypsin inhibitor in FSP or FDP slide agglutination
test? Answer: Trypsin is an antifibrinolytic agent so it prevents invitro
fibrinolysis, allowing the test to detect only the fibrinolysis that occurred in the
pt prior to the blood collection.
What is the diagnosis if a patient has a + FSP and negative D-Dimer? Answer:
Primary or pathologic fibrinogenolysis
What is the diagnosis if a patient has a + FSP and + D-Dimer? Answer: DIC or
thrombosis
List the factors in the extrinsic system? Answer: III and VII
List the factors in the intrinsic system? Answer: XII, XI, IX, VIII
What is the therapeutic range for INR? Answer: 2.0-3.0 for most patients on
coumadin
What are the reagents used in the PT? Answer: Rabbit thromboplastin
Calcium in the thromboplastin
What are the reagents used in the PTT Answer: Activated partial
thromboplastin (Actin)
Calcium Chloride
what is the purpose of Rabit Thromboplastin in PT? Answer: Acts as tissue
factor III to activate factor VII to start the extrinstic system.
what is the purpose of Calcium in the thromboplastin in PT? Answer: adds
back the calcium bound by the sodium citrate anticoagulant in the collection
tube.
What is the purpose of Activated partial thromboplastin (Actin) in PTT?
Answer: contains a commercial phospholipid and a negatively charge particle
like kaolin or ellagic acid to activate Factor XII to start the intrinsic system.
