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Verified Pharmacology- An Introduction 8th Edition by Henry Hitner, Barbara T (1).pdf

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Verified Pharmacology- An Introduction 8th Edition by Henry Hitner, Barbara T (1).pdf

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Name: Score:


20 Multiple choice questions

Term 1 of 20
42) Which of the following would not be considered an adverse effect of taking an oral
antibiotic?



A) Extravasation
B) Diarrhea
C) Nausea
D) Vomiting

42) A. Extravasation

Oral drugs often cause nausea, vomiting, and diarrhea because of gastrointestinal (GI)
irritation.

46) D. Idiosyncrasy

A few adverse drug effects are not dose-dependent. These effects, such as drug
idiosyncrasy and drug allergy, are determined by individual variation.

27) C. agonists


Drugs that bind to specific receptors and produce a drug action are called agonists.

49) B. generic name


The nonproprietary name is more commonly referred to as the generic name.

,Term 2 of 20

46) Which of the following would not be considered a dose-dependent adverse effect of a drug?



A) Nausea
B) Liver damage
C) Kidney damage
D) Idiosyncrasy

23) B. The toxic effects of a drug can be life-threatening.

Toxic effects, or toxicity, implies drug poisoning, the consequences of which can be
extremely harmful and may be life-threatening.


37) C. Effective dose 50


The effective dose 50 (ED50) can be derived from a drug-response curve and used to
compare the potency of drugs that produce the same response.

46) D. Idiosyncrasy

A few adverse drug effects are not dose-dependent. These effects, such as drug
idiosyncrasy and drug allergy, are determined by individual variation.

24) D. A pure drug is a chemical compound with a specific chemical structure.

Every pure drug is a chemical compound with a specific chemical structure.

, Definition 3 of 20
6) A. be safe and effective.


According to the FDA, every drug must fulfill two major requirements before it can be approved
for use in humans: efficacy (proof of effectiveness) and safety. All drugs will produce toxic and
adverse effects if taken in excessive amounts. The therapeutic index helps determine the relative
safety of a drug.

6) In order for the Food and Drug Administration (FDA) to approve the use of a drug, the
drug must:



A) be safe and effective.
B) not cause idiosyncratic responses.
C) be safe at any dose.
D) have a low therapeutic index.
E) be able to treat more than one condition.

50) Orion laboratories, a pharmaceutical manufacturing company, manufactures the drug
cetirizine and markets the tablets under the name "Alzer." In this case, cetirizine is the _____
name of the drug.



A) proprietary
B) generic
C) trade
D) brand

12) A drug's mechanism of action is best defined as:



A) the method through which the drug is eliminated from the body.
B) the way two drugs compete with each other in the body.
C) the way the drug works within the body.
D) the method in which the drug is administered.

39) What type of curve should be used for representing data when a proper dosing
frequency is being determined?

A) A time-response curve
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