TEST #1 BIO 163
1. Which of the following might trigger erythropoiesis?
A) hypoxia of EPO-producing cells
B) decreased tissue demand for oxygen
C) an increased number of RBCs
D) moving to a lower altitude
2. The plasma protein that is the major contributor to osmotic pressure is ________.
A) fibrinogen
B) albumin
C) alpha globulin
D) gamma globulin
3. All of the following can be expected with polycythemia except ________.
A) high hematocrit
B) low blood viscosity
C) increased blood volume
D) high blood pressure
4. The blood volume of a typical adult averages
A) 1 Liter
B) 3 Liters
C) 5 Liters
D) 7 Liters
5. Which of the following is not a structural characteristic that contributes to erythrocyte gas
transport functions?
A) biconcave shape
B) hemoglobin containing-sack
C) high mitotic (mitosis) activity
D) all of these contribute to gas transport
6. The conversion of prothrombin to thrombin is important in hemostasis because thrombin
________
A) helps to break down the fibrin mesh
B) leads to the conversion of soluble fibrinogen to fibrin
C) activates the intrinsic pathway
D) works as an anticoagulant
7. Heparin from endothelial cells works as ________
A) a pro-coagulant by stimulating the intrinsic pathway
B) a pro-coagulant by inhibiting the extrinsic pathway
C) an anti-coagulant by inhibiting the intrinsic pathway
D) an anti-coagulant by stimulating the extrinsic pathway
, 8. Which of the following is not a cause of bleeding disorders?
A) thrombocytopenia, a condition of decreased circulating platelets
B) excess secretion of platelet-derived growth factor (PDGF)
C) a defect in the clotting cascade
D) vitamin K deficiency
9. Which of the following is characteristic of all leukocytes?
A) They have a nucleus.
B) They have cytoplasmic granules.
C) They are phagocytic.
D) They are the most numerous of the formed elements in blood.
10. Platelets ________.
A) stick to the damaged area of a blood vessel and help seal the break
B) have a life span of about 120 days
C) are the precursors of leukocytes
D) have multiple nuclei
11. Which sequence is correct for the following events?
1. fibrinogen → fibrin
2. clot retraction
3. prothrombin → thrombin
4. formation of prothrombin activator
A) 3, 4, 1, 2
B) 1, 2, 3, 4
C) 4, 3, 1, 2
D) 3, 2, 1, 4
12. Activation of the _________ pathway involves exposure to tissue factor and while damage
to the endothelium exposing underlying collagen activates the _____________ pathway.
Activation of the __________ pathway takes longer because more steps are involved.
A) Intrinsic, Extrinsic, Intrinsic
B) Extrinsic, Intrinsic, Extrinsic
C) Intrinsic, Extrinsic, Extrinsic
D) Extrinsic, Intrinsic, Intrinsic
1. Which of the following might trigger erythropoiesis?
A) hypoxia of EPO-producing cells
B) decreased tissue demand for oxygen
C) an increased number of RBCs
D) moving to a lower altitude
2. The plasma protein that is the major contributor to osmotic pressure is ________.
A) fibrinogen
B) albumin
C) alpha globulin
D) gamma globulin
3. All of the following can be expected with polycythemia except ________.
A) high hematocrit
B) low blood viscosity
C) increased blood volume
D) high blood pressure
4. The blood volume of a typical adult averages
A) 1 Liter
B) 3 Liters
C) 5 Liters
D) 7 Liters
5. Which of the following is not a structural characteristic that contributes to erythrocyte gas
transport functions?
A) biconcave shape
B) hemoglobin containing-sack
C) high mitotic (mitosis) activity
D) all of these contribute to gas transport
6. The conversion of prothrombin to thrombin is important in hemostasis because thrombin
________
A) helps to break down the fibrin mesh
B) leads to the conversion of soluble fibrinogen to fibrin
C) activates the intrinsic pathway
D) works as an anticoagulant
7. Heparin from endothelial cells works as ________
A) a pro-coagulant by stimulating the intrinsic pathway
B) a pro-coagulant by inhibiting the extrinsic pathway
C) an anti-coagulant by inhibiting the intrinsic pathway
D) an anti-coagulant by stimulating the extrinsic pathway
, 8. Which of the following is not a cause of bleeding disorders?
A) thrombocytopenia, a condition of decreased circulating platelets
B) excess secretion of platelet-derived growth factor (PDGF)
C) a defect in the clotting cascade
D) vitamin K deficiency
9. Which of the following is characteristic of all leukocytes?
A) They have a nucleus.
B) They have cytoplasmic granules.
C) They are phagocytic.
D) They are the most numerous of the formed elements in blood.
10. Platelets ________.
A) stick to the damaged area of a blood vessel and help seal the break
B) have a life span of about 120 days
C) are the precursors of leukocytes
D) have multiple nuclei
11. Which sequence is correct for the following events?
1. fibrinogen → fibrin
2. clot retraction
3. prothrombin → thrombin
4. formation of prothrombin activator
A) 3, 4, 1, 2
B) 1, 2, 3, 4
C) 4, 3, 1, 2
D) 3, 2, 1, 4
12. Activation of the _________ pathway involves exposure to tissue factor and while damage
to the endothelium exposing underlying collagen activates the _____________ pathway.
Activation of the __________ pathway takes longer because more steps are involved.
A) Intrinsic, Extrinsic, Intrinsic
B) Extrinsic, Intrinsic, Extrinsic
C) Intrinsic, Extrinsic, Extrinsic
D) Extrinsic, Intrinsic, Intrinsic
