pharm exam 1 Galen questions with answers |\ |\ |\ |\ |\ |\
When the drug is in bloodstream after administration, is
|\ |\ |\ |\ |\ |\ |\ |\ |\
disintegrated out of stomach this is called? |\ |\ |\ |\ |\ |\ |\
A. metabolism
|\
B. absorption
|\
C. excretion
|\
D. distribution - CORRECT ANSWERS ✔✔B
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The movement of a drug from circulatory system to body tissues
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
is called what?
|\ |\
A. distribution
|\
B. metabolism
|\
C. excretion
|\
D. absorption - CORRECT ANSWERS ✔✔A
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This occurs when a drug is altered in chemical structure, most
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
are done in the liver.
|\ |\ |\ |\
A. excretion
|\
B. distribution
|\
C. absorption
|\
D. metabolism (biotransformation) - CORRECT ANSWERS ✔✔D
|\ |\ |\ |\ |\ |\
Elimination of drug from body through the following: kidneys,
|\ |\ |\ |\ |\ |\ |\ |\ |\
liver, feces, lungs, saliva, sweat, breast milk.
|\ |\ |\ |\ |\ |\ |\
,A. excretion
|\
B. distribution
|\
C. metabolism
|\
D. absorption - CORRECT ANSWERS ✔✔A
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100% of a drug is used when it is given by which route?
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A. intramuscular (IM)
|\ |\
B. intravenously (IV)
|\ |\
C. subcutaneously (subq)
|\ |\
D. orally (PO) - CORRECT ANSWERS ✔✔B
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1st pass effect goes from the ____ to the ____.
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
Only ____ % of med is going to make it through bloodstream due
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
to this process. - CORRECT ANSWERS ✔✔-stomach, liver
|\ |\ |\ |\ |\ |\ |\
-30%
What are the two routes that can skip the 1st pass effect?
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A. IM, sublingual
|\ |\
B. IV, sublingual
|\ |\
C. IM, subq
|\ |\
D. IV, subq - CORRECT ANSWERS ✔✔B
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,When drug comes out of the first pass effect, it can go into the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
blood & be used in some way, the % of administered drug
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
available for activity is called? |\ |\ |\ |\
A. peak
|\ |\
B. onset
|\ |\
C. trough
|\
D. bioavailable - CORRECT ANSWERS ✔✔D
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What in the blood have receptor sites that will grab onto, hold
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
onto med and decreased therapeutic effect on drug?
|\ |\ |\ |\ |\ |\ |\
A. carbs
|\
B. electrolytes
|\
C. proteins
|\
D. cells - CORRECT ANSWERS ✔✔C
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What is it called when the drug causes the effect & do not get
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
taken up by proteins in blood?
|\ |\ |\ |\ |\
A. free drug
|\ |\
B. extended release drug
|\ |\ |\
C. protein binding drug - CORRECT ANSWERS ✔✔A
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When you take TWO high protein binding drugs the effect of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
med is going to be _____ effect on the body.
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
They are going to compete with one another for ____ sites which
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
makes them become ____ - CORRECT ANSWERS ✔✔higher,
|\ |\ |\ |\ |\ |\ |\ |\
, protein, free drugs |\ |\
When a med has a ____ half life you may only need to take that
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
med a couple times a week.
|\ |\ |\ |\ |\ |\
When a med has a ____ half life, it may need to be taken more
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
often because when it ____ it becomes ____ therapeutic -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔long, |\ |\ |\
short, decreases, less|\ |\
When a drug becomes therapeutic this is called?
|\ |\ |\ |\ |\ |\ |\ |\
A. onset
|\ |\
B. peak
|\
C. duration of action
|\ |\ |\
The length of time a drug exerts a therapeutic effect is called?
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A. duration of action
|\ |\ |\
B. peak
|\
C. onset
|\ |\
This occurs when a drug reaches its highest concentration in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
blood.
A. onset
|\
When the drug is in bloodstream after administration, is
|\ |\ |\ |\ |\ |\ |\ |\ |\
disintegrated out of stomach this is called? |\ |\ |\ |\ |\ |\ |\
A. metabolism
|\
B. absorption
|\
C. excretion
|\
D. distribution - CORRECT ANSWERS ✔✔B
|\ |\ |\ |\ |\
The movement of a drug from circulatory system to body tissues
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
is called what?
|\ |\
A. distribution
|\
B. metabolism
|\
C. excretion
|\
D. absorption - CORRECT ANSWERS ✔✔A
|\ |\ |\ |\ |\
This occurs when a drug is altered in chemical structure, most
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
are done in the liver.
|\ |\ |\ |\
A. excretion
|\
B. distribution
|\
C. absorption
|\
D. metabolism (biotransformation) - CORRECT ANSWERS ✔✔D
|\ |\ |\ |\ |\ |\
Elimination of drug from body through the following: kidneys,
|\ |\ |\ |\ |\ |\ |\ |\ |\
liver, feces, lungs, saliva, sweat, breast milk.
|\ |\ |\ |\ |\ |\ |\
,A. excretion
|\
B. distribution
|\
C. metabolism
|\
D. absorption - CORRECT ANSWERS ✔✔A
|\ |\ |\ |\ |\
100% of a drug is used when it is given by which route?
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A. intramuscular (IM)
|\ |\
B. intravenously (IV)
|\ |\
C. subcutaneously (subq)
|\ |\
D. orally (PO) - CORRECT ANSWERS ✔✔B
|\ |\ |\ |\ |\ |\
1st pass effect goes from the ____ to the ____.
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
Only ____ % of med is going to make it through bloodstream due
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
to this process. - CORRECT ANSWERS ✔✔-stomach, liver
|\ |\ |\ |\ |\ |\ |\
-30%
What are the two routes that can skip the 1st pass effect?
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A. IM, sublingual
|\ |\
B. IV, sublingual
|\ |\
C. IM, subq
|\ |\
D. IV, subq - CORRECT ANSWERS ✔✔B
|\ |\ |\ |\ |\ |\
,When drug comes out of the first pass effect, it can go into the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
blood & be used in some way, the % of administered drug
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
available for activity is called? |\ |\ |\ |\
A. peak
|\ |\
B. onset
|\ |\
C. trough
|\
D. bioavailable - CORRECT ANSWERS ✔✔D
|\ |\ |\ |\ |\
What in the blood have receptor sites that will grab onto, hold
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
onto med and decreased therapeutic effect on drug?
|\ |\ |\ |\ |\ |\ |\
A. carbs
|\
B. electrolytes
|\
C. proteins
|\
D. cells - CORRECT ANSWERS ✔✔C
|\ |\ |\ |\ |\
What is it called when the drug causes the effect & do not get
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
taken up by proteins in blood?
|\ |\ |\ |\ |\
A. free drug
|\ |\
B. extended release drug
|\ |\ |\
C. protein binding drug - CORRECT ANSWERS ✔✔A
|\ |\ |\ |\ |\ |\ |\
When you take TWO high protein binding drugs the effect of the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
med is going to be _____ effect on the body.
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
They are going to compete with one another for ____ sites which
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
makes them become ____ - CORRECT ANSWERS ✔✔higher,
|\ |\ |\ |\ |\ |\ |\ |\
, protein, free drugs |\ |\
When a med has a ____ half life you may only need to take that
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
med a couple times a week.
|\ |\ |\ |\ |\ |\
When a med has a ____ half life, it may need to be taken more
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
often because when it ____ it becomes ____ therapeutic -
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
CORRECT ANSWERS ✔✔long, |\ |\ |\
short, decreases, less|\ |\
When a drug becomes therapeutic this is called?
|\ |\ |\ |\ |\ |\ |\ |\
A. onset
|\ |\
B. peak
|\
C. duration of action
|\ |\ |\
The length of time a drug exerts a therapeutic effect is called?
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
A. duration of action
|\ |\ |\
B. peak
|\
C. onset
|\ |\
This occurs when a drug reaches its highest concentration in
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
blood.
A. onset
|\
