UWSA 2 STUDY GUIDE UPDATED QUESTIONS AND
ANSWERS RATED A+
✔✔Common immunosuppresives that cause nephrotoxicity - ✔✔calcineurin inhibitors
tac and cyclosporine
rise in BUN, Cr, and Bp
✔✔who is metoclopramide contraindicated in - ✔✔Parkinson patients
metoclopramide can exacerbate or cause de novo parkinsonian symptoms and trigger
EPS due to antagonisting effect on dopamine receptors
✔✔alkaptonuria - ✔✔defect in homogentisic acid dioxygenase
impaired tyrosine metabolism
urine turns black on air
can cause osteoarthropathy
✔✔acute ischemia and electrolytes around the cells - ✔✔depletion of intracellular ATP
stores
N/K ATPase doesn't work
extracellular Na leaks in
+ Cl and HTO
intracellular K leaks out
✔✔What kind of receptors stimulate renin release - ✔✔beta 1
✔✔female athlete triad - ✔✔disordered eating
amenorrhea
osteoporosis
2/2 hypogonadotropic amenorrhea
✔✔what conditions are assoc w estrogen deficiency - ✔✔infertility
vaginal atrophy
breast atrophy
osteopenia
, ✔✔pancreatic pseudocyst - ✔✔collection of fluid, pancreatic enzymes, and blood
well circumscribed fluid collection compressing the IVC
✔✔Warfarin vs heparin in pregnancy - ✔✔warfarin is lipophilic and could cross the
placenta
heparin is charged/polar, water soluble, will not cross the placenta
✔✔what type of genetic change allows an influenza virus to jump species - ✔✔genetic
reassortment
2 distinct viruses infect the same cell and the HA from one and the NA from the other
are packaged together into new virion
novel strain
antigenic shift
✔✔what causes exophthalmos in graves disease - ✔✔glycosaminoglycan synthesis by
fibroblasts
✔✔Crypts of lieberkuhn - ✔✔contain stem cells to replace goblet cells
and paneth cells - secrete defensins, lysozymes, TNF
✔✔cystic hygromas - ✔✔cystic lymphatic malformations that most commonly involve
the loose areolar tissue of the head and neck and occur more frequently on the left side
✔✔Mechanism of tardive dyskinesia - ✔✔upregulation of dopamine receptors
long-term blockade of DA receptors causes upregulation and compensatory
supersensitivity
✔✔How does PE affect hemodynamics - ✔✔Increased CVP
Decreased CO
increased SVR
✔✔What nerve is injured in a mid shaft humerus fracture - ✔✔radial nerve
it tracks posteriorly within the radial groove
weakness/paralysis of the hand and finger extensor muscles
ANSWERS RATED A+
✔✔Common immunosuppresives that cause nephrotoxicity - ✔✔calcineurin inhibitors
tac and cyclosporine
rise in BUN, Cr, and Bp
✔✔who is metoclopramide contraindicated in - ✔✔Parkinson patients
metoclopramide can exacerbate or cause de novo parkinsonian symptoms and trigger
EPS due to antagonisting effect on dopamine receptors
✔✔alkaptonuria - ✔✔defect in homogentisic acid dioxygenase
impaired tyrosine metabolism
urine turns black on air
can cause osteoarthropathy
✔✔acute ischemia and electrolytes around the cells - ✔✔depletion of intracellular ATP
stores
N/K ATPase doesn't work
extracellular Na leaks in
+ Cl and HTO
intracellular K leaks out
✔✔What kind of receptors stimulate renin release - ✔✔beta 1
✔✔female athlete triad - ✔✔disordered eating
amenorrhea
osteoporosis
2/2 hypogonadotropic amenorrhea
✔✔what conditions are assoc w estrogen deficiency - ✔✔infertility
vaginal atrophy
breast atrophy
osteopenia
, ✔✔pancreatic pseudocyst - ✔✔collection of fluid, pancreatic enzymes, and blood
well circumscribed fluid collection compressing the IVC
✔✔Warfarin vs heparin in pregnancy - ✔✔warfarin is lipophilic and could cross the
placenta
heparin is charged/polar, water soluble, will not cross the placenta
✔✔what type of genetic change allows an influenza virus to jump species - ✔✔genetic
reassortment
2 distinct viruses infect the same cell and the HA from one and the NA from the other
are packaged together into new virion
novel strain
antigenic shift
✔✔what causes exophthalmos in graves disease - ✔✔glycosaminoglycan synthesis by
fibroblasts
✔✔Crypts of lieberkuhn - ✔✔contain stem cells to replace goblet cells
and paneth cells - secrete defensins, lysozymes, TNF
✔✔cystic hygromas - ✔✔cystic lymphatic malformations that most commonly involve
the loose areolar tissue of the head and neck and occur more frequently on the left side
✔✔Mechanism of tardive dyskinesia - ✔✔upregulation of dopamine receptors
long-term blockade of DA receptors causes upregulation and compensatory
supersensitivity
✔✔How does PE affect hemodynamics - ✔✔Increased CVP
Decreased CO
increased SVR
✔✔What nerve is injured in a mid shaft humerus fracture - ✔✔radial nerve
it tracks posteriorly within the radial groove
weakness/paralysis of the hand and finger extensor muscles
