,Table of contents
Chapter 1 - Cellular Biology _________________________________________________________________________________________ 3
Chapter 2 - Altered Cellular and Tissue Biology Environmental Agents 16 Chapter 3 - The Cellular
Environment Fluids and Electrolytes Acids and
Bases _____________________________________________________________________________________________________________________ 28
Chapter 4 - Genes and Genetic Diseases _______________________________________________________________________________ 41
Chapter 5 - Genes Environment-Lifestyle and Common Diseases __________________________________________________ 51
Chapter 6 - Epigenetics and Disease ___________________________________________________________________________________ 59
Chapter 7 - Innate Immunity Inflammation ___________________________________________________________________________ 64
Chapter 8 - Adaptive Immunity ________________________________________________________________________________________ 78
Chapter 9 - Alterations in Immunity and Inflammation ___________________________________________________________ 89
Chapter 10 - Infection _________________________________________________________________________________________________ 102
Chapter 11 - Stress and Disease_____________________________________________________________________________________ 110
Chapter 12 - Cancer Biology _________________________________________________________________________________________ 117
Chapter 13 - Cancer Epidemiology _________________________________________________________________________________ 129
Chapter 14 - Cancer in Children_____________________________________________________________________________________ 135
Chapter 15 - Structure and Function of the Neurologic System __________________________________________________ 140
Chapter 16 - Pain Temperature Regulation Sleep and Sensory Function 151 Chapter 17 - Alterations in Cognitive
Systems Cerebral Hemodynamics and
Motor Function ________________________________________________________________________________________________________ 165
Chapter 18 - Disorders of the Central and Peripheral Nervous Systems and
the Neuromuscular Junction ________________________________________________________________________________________ 179
Chapter 19 - Neurobiology of Schizophrenia Mood Disorders and Anxiety Disorders 189
Chapter 20 - Alterations of Neurologic Function in Children ____________________________________________________ 195
Chapter 21 - Mechanisms of Hormonal Regulation 202 Chapter
22 - Alterations of Hormonal Regulation ___________________________________________________________________________ 211
Chapter 23 - Obesity and Disorders of Nutrition NEW ____________________________________________________________ 223
Chapter 24 - Structure and Function of the Reproductive Systems ______________________________________________ 228
Chapter 25 - Alterations of the Female Reproductive System ____________________________________________________ 237
Chapter 26 - Alterations of the Male Reproductive System _______________________________________________________ 246
,Chapter 27 - Sexually Transmitted Infections __________________________________________ 252
Chapter 28 - Structure and Function of the Hematologic System _____________________ 260
Chapter 29 - Alterations of Erythrocyte Platelet and Hemostatic Function__________ 270
Chapter 30 - Alterations of Leukocyte and Lymphoid Function ______________________ 280
Chapter 31 - Alterations of Hematologic Function in Children _______________________ 287
Chapter 32 - Structure and Function of the Cardiovascular and Lymphatic Systems
______________________________________________________________________________________________ 297
Chapter 33 - Alterations of Cardiovascular Function __________________________________ 309
Chapter 34 - Alterations of Cardiovascular Function in Children _____________________ 323
Chapter 35 - Structure and Function of the Pulmonary System ______________________ 331
Chapter 36 - Alterations of Pulmonary Function _______________________________________ 341
Chapter 37 - Alterations of Pulmonary Function in Children _________________________ 357
Chapter 38 - Structure and Function of the Renal and Urologic Systems ____________ 365
Chapter 39 - Alterations of Renal and Urinary Function ______________________________ 375
Chapter 40 - Alterations of Renal and Urinary Tract Function in Children __________ 385
Chapter 41 - Structure and Function of the Digestive System ________________________ 393
Chapter 42 - Alterations of Digestive Function _________________________________________ 404
Chapter 43 - Alterations of Digestive Function in Children ___________________________ 415
Chapter 44 - Structure and Function of the Musculoskeletal System_________________ 424
Chapter 45 - Alterations of Musculoskeletal Function _________________________________ 436
Chapter 46 - Alterations of Musculoskeletal Function in Children____________________ 448
Chapter 47 - Structure Function and Disorders of the Integument ___________________ 457
Chapter 48 - Alterations of the Integument in Children _______________________________ 468
Chapter 49 - Shock Multiple Organ Dysfunction Syndrome and Burns in
Adults ______________________________________________________________________________________ 476
Chapter 50 - Shock Multiple Organ Dysfunction Syndrome and Burns in
, Children ____________________________________________________________________________________ 483