NCLEX Psychiatric/Mental Health Drugs –2025-2026 Complete
Study Guide with Pharmacology Review and Exam Preparation
with Verified Questions and Correct Answers||Latest version
A client has been receiving fluphenazine for several months. The
nurse will assess the client for which side effects? Select all that
apply.
A. Tremors
B. Excess salivation
C. Rambling speech
D. Reluctance to converse
E. Uncoordinated movement of extremities - Answer-A. Tremors
E. Uncoordinated movement of extremities
The nurse is teaching a client who is receiving a monoamine oxidase
inhibitor about dietary restrictions. The nurse plans to caution the
client to avoid which foods?
A. Pork, spinach, and fresh oysters
B. Milk, grapes, and meat tenderizers
C. Cheese, beer, and products with chocolate
D. Leafy green vegetables, fresh apples, and ice cream - Answer-C.
Cheese, beer, and products with chocolate
A nurse is counseling a client who abuses cocaine. The nurse
recognizes that this drug is representative of which drug category?
A. An opioid
B. A stimulant
C. A barbiturate
D. A hallucinogen - Answer-B. A stimulant
pg. 1
,What is the best drug of choice for treating obsessive-compulsive
disorder?
A. Imipramine
B. Lithium salts
C. Amitriptyline
D. Clomipramine - Answer-D. Clomipramine
Which drug may lead to bruxism (a condition in which you grind,
gnash or clench your teeth)?
A. Vilazodone
B. Isocarboxazid
C. Clomipramine
D. Levomilnacipran - Answer-D. Levomilnacipran
Which drug is used to treat both generalized anxiety disorder and
depression?
A. Fluoxetine
B. Bupropion
C. Duloxetine
D. Mirtazapine - Answer-C. Duloxetine
Which drug is contraindicated in a pregnant client diagnosed with
bipolar disorder?
A. Sertraline
B. Paroxetine
C. Venlafaxine
D. Despramine - Answer-B. Paroxetine
A healthcare provider prescribes aripiprazole 15 mg by mouth once a
day for a client with the diagnosis of schizophrenia. The hospital
pharmacy sends aripiprazole 5 mg/tablet. How many tablets will the
pg. 2
,nurse administer? Record your answer as a whole number. ____
tablet(s) - Answer-3
A client has been receiving lithium for the past 2 weeks for the
treatment of bipolar disorder, manic phase. What will the nurse
include in the teaching plan for this client?
A. A diuretic is necessary for anyone taking lithium.
B. Lithium must be taken for the rest of the client's life.
C. The blood level of lithium must be checked every month.
D. A low-sodium diet must be followed while lithium is being taken. -
Answer-C. The blood level of lithium must be checked every month.
A client with schizophrenia who is receiving an antipsychotic
medication begins to exhibit a shuffling gait and tremors. The primary
healthcare provider prescribes the anticholinergic medication
benztropine, 2 mg daily. What will the nurse assess the client for daily
when administering these medications together?
A. Constipation
B. Hypertension
C. Increased salivation
D. Excessive perspiration - Answer-A. Constipation
A healthcare provider prescribes disulfiram for a client who abuses
alcohol. The nurse teaches the client that disulfiram will have which
action?
A. Affect short-term memory
B. Permit a healthier lifestyle
C. Allow the client to tolerate small amounts of alcohol
D. Cause a severe adverse reaction if alcohol is consumed - Answer-
D. Cause a severe adverse reaction if alcohol is consumed
pg. 3
, A client is receiving haloperidol for agitation, and the nurse is
monitoring the client for side effects. Which response identified by
the nurse is unrelated to an extrapyramidal tract effect?
A. Akathisia
B. Opisthotonos
C. Oculogyric crisis
D. Hypertensive crisis - Answer-D. Hypertensive crisis
A nurse is administering medications to clients on a psychiatric unit.
What does the nurse identify as the reason that so many psychiatric
clients are given the drug benztropine or trihexyphenidyl in
conjunction with the phenothiazine-derivative neuroleptic
medications?
A. They reduce postural hypotension.
B. They potentiate the effects of the neuroleptic drug.
C. They combat the extrapyramidal side effects of the neuroleptic
drug.
D. They ameliorate the depression that may accompany
schizophrenia. - Answer-C. They combat the extrapyramidal side
effects of the neuroleptic drug.
Which atypical antipsychotics are approved for long-term use to
prevent the recurrence of mood episodes in clients with bipolar
disease? Select all that apply.
A. Olanzapine
B. Quetiapine
C. Ziprasidone
D. Risperidone
E. Aripiprazole - Answer-A. Olanzapine
C. Ziprasidone
pg. 4
Study Guide with Pharmacology Review and Exam Preparation
with Verified Questions and Correct Answers||Latest version
A client has been receiving fluphenazine for several months. The
nurse will assess the client for which side effects? Select all that
apply.
A. Tremors
B. Excess salivation
C. Rambling speech
D. Reluctance to converse
E. Uncoordinated movement of extremities - Answer-A. Tremors
E. Uncoordinated movement of extremities
The nurse is teaching a client who is receiving a monoamine oxidase
inhibitor about dietary restrictions. The nurse plans to caution the
client to avoid which foods?
A. Pork, spinach, and fresh oysters
B. Milk, grapes, and meat tenderizers
C. Cheese, beer, and products with chocolate
D. Leafy green vegetables, fresh apples, and ice cream - Answer-C.
Cheese, beer, and products with chocolate
A nurse is counseling a client who abuses cocaine. The nurse
recognizes that this drug is representative of which drug category?
A. An opioid
B. A stimulant
C. A barbiturate
D. A hallucinogen - Answer-B. A stimulant
pg. 1
,What is the best drug of choice for treating obsessive-compulsive
disorder?
A. Imipramine
B. Lithium salts
C. Amitriptyline
D. Clomipramine - Answer-D. Clomipramine
Which drug may lead to bruxism (a condition in which you grind,
gnash or clench your teeth)?
A. Vilazodone
B. Isocarboxazid
C. Clomipramine
D. Levomilnacipran - Answer-D. Levomilnacipran
Which drug is used to treat both generalized anxiety disorder and
depression?
A. Fluoxetine
B. Bupropion
C. Duloxetine
D. Mirtazapine - Answer-C. Duloxetine
Which drug is contraindicated in a pregnant client diagnosed with
bipolar disorder?
A. Sertraline
B. Paroxetine
C. Venlafaxine
D. Despramine - Answer-B. Paroxetine
A healthcare provider prescribes aripiprazole 15 mg by mouth once a
day for a client with the diagnosis of schizophrenia. The hospital
pharmacy sends aripiprazole 5 mg/tablet. How many tablets will the
pg. 2
,nurse administer? Record your answer as a whole number. ____
tablet(s) - Answer-3
A client has been receiving lithium for the past 2 weeks for the
treatment of bipolar disorder, manic phase. What will the nurse
include in the teaching plan for this client?
A. A diuretic is necessary for anyone taking lithium.
B. Lithium must be taken for the rest of the client's life.
C. The blood level of lithium must be checked every month.
D. A low-sodium diet must be followed while lithium is being taken. -
Answer-C. The blood level of lithium must be checked every month.
A client with schizophrenia who is receiving an antipsychotic
medication begins to exhibit a shuffling gait and tremors. The primary
healthcare provider prescribes the anticholinergic medication
benztropine, 2 mg daily. What will the nurse assess the client for daily
when administering these medications together?
A. Constipation
B. Hypertension
C. Increased salivation
D. Excessive perspiration - Answer-A. Constipation
A healthcare provider prescribes disulfiram for a client who abuses
alcohol. The nurse teaches the client that disulfiram will have which
action?
A. Affect short-term memory
B. Permit a healthier lifestyle
C. Allow the client to tolerate small amounts of alcohol
D. Cause a severe adverse reaction if alcohol is consumed - Answer-
D. Cause a severe adverse reaction if alcohol is consumed
pg. 3
, A client is receiving haloperidol for agitation, and the nurse is
monitoring the client for side effects. Which response identified by
the nurse is unrelated to an extrapyramidal tract effect?
A. Akathisia
B. Opisthotonos
C. Oculogyric crisis
D. Hypertensive crisis - Answer-D. Hypertensive crisis
A nurse is administering medications to clients on a psychiatric unit.
What does the nurse identify as the reason that so many psychiatric
clients are given the drug benztropine or trihexyphenidyl in
conjunction with the phenothiazine-derivative neuroleptic
medications?
A. They reduce postural hypotension.
B. They potentiate the effects of the neuroleptic drug.
C. They combat the extrapyramidal side effects of the neuroleptic
drug.
D. They ameliorate the depression that may accompany
schizophrenia. - Answer-C. They combat the extrapyramidal side
effects of the neuroleptic drug.
Which atypical antipsychotics are approved for long-term use to
prevent the recurrence of mood episodes in clients with bipolar
disease? Select all that apply.
A. Olanzapine
B. Quetiapine
C. Ziprasidone
D. Risperidone
E. Aripiprazole - Answer-A. Olanzapine
C. Ziprasidone
pg. 4
