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NURS 5315 Exam 2 (75 Questions) – Advanced Pathophysiology: Hematology, Anemia, Coagulation, Leukemia

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This document features 75 high-yield, exam-verified questions and answers for NURS 5315: Advanced Pathophysiology, specifically covering Exam 2 content for the 2025/2026 academic year. The material focuses on critical hematologic concepts and conditions encountered in advanced nursing education and clinical practice. Covered topics include interpretation of complete blood count (CBC) parameters, classification and causes of anemia (iron deficiency, folate, pernicious, anemia of chronic disease), primary and secondary hemostasis, the coagulation cascade, clotting factor disorders, and platelet pathophysiology. Additionally, the document dives into hematologic malignancies, providing detailed Q&A coverage of acute and chronic leukemias (ALL, AML, CLL, CML), lymphomas (Hodgkin and Non-Hodgkin), and multiple myeloma. Pathophysiological mechanisms, diagnostic markers (e.g., BCR-ABL1, Philadelphia chromosome), clinical presentations, and pharmacological interventions (warfarin, heparin, aspirin) are all discussed thoroughly. This makes the material especially valuable for reinforcing applied knowledge in both academic and clinical settings. Recommended for students enrolled in: – Nurse Practitioner (NP) programs: FNP, AGNP, ACNP – Advanced Practice Registered Nurse (APRN) tracks – BSN and RN-to-BSN bridge programs – MSN and DNP academic pathways – Courses in advanced pathophysiology, clinical assessment, hematology, and internal medicine This resource is ideal for midterm/final preparation, certification readiness, or focused revision on hematologic disorders and coagulation for nursing professionals. Keywords: NURS 5315, advanced pathophysiology, hematology, anemia, iron deficiency, folate deficiency, vitamin B12 deficiency, sickle cell anemia, coagulation cascade, platelet function, thrombocytopenia, hemophilia, DIC, leukemia, lymphoma, multiple myeloma, BCR-ABL1, Philadelphia chromosome, hemostasis, warfarin, heparin, PT, aPTT

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NURS 5315 Exam 2: Concept and
Clinical Condition Part II 2025/2026
Exam Questions and Verified Answers |
Already Graded A+



White Blood Cell (WBC) Normal Values - 🧠 ANSWER ✔✔5,000 - 10,000

mm3


What is the normal range for platelets? - 🧠 ANSWER ✔✔150,000-

400,000/mm3

Red Blood Cell (RBC) Normal Ranges for Males and Females - 🧠

ANSWER ✔✔Males: 4.7 - 6.1


Females: 4.2 - 5.4

Hemoglobin (Hbg) measures the total hemoglobin in the blood and

decreased levels indicate anemia. What are the Normal Range for Males

and Females? - 🧠 ANSWER ✔✔Males: 14-18

,Females: 12-16

Hemarocrit (HCT) measures the percentage of total RBCs. What are the

normal ranges for Males and Females? - 🧠 ANSWER ✔✔Males: 42-52%


Females: 37-47%

Mean Corpuscular Volume (MCV) measures the average size of RBC, and

helps with the classification of anemia. What is the normal range for MCV?

- 🧠 ANSWER ✔✔80-100mm3


What is the normal range for Reticulocyte Count and what does it

measure? - 🧠 ANSWER ✔✔Normal Range: 0.5% - 2%


Measure of immature RBC and is an indicator of how the bone marrow is

responding to anemia.

An elevated number of Bands (immature neutrophils) can indicate the

presence of an ____. - 🧠 ANSWER ✔✔Infection


What are the key components of a hemoglobin molecule? - 🧠 ANSWER

✔✔4 heme groups (4 oxygen molecules)


alpha polypeptide (globin) chain

beta polypeptide (golbin) chain

, Where would you see HbA? - 🧠 ANSWER ✔✔In 92% of adults


What type of hemoglobin do you see in increased amounts in Diabetes

patients? - 🧠 ANSWER ✔✔HbA1c


Where do you see HbA2? - 🧠 ANSWER ✔✔5% of adults


Increased in Beta thalassemia (inherited disorder where the body doesn't

make enough hemoglobin)

Which hemoglobin appears from the third through 9th month of gestation ,

promotes O2 transfer across platelets and is increased in Beta

thalassemia? - 🧠 ANSWER ✔✔HbF


Where do you see Hb Gower 1, Hb Gower 2, and Hb Portland? - 🧠

ANSWER ✔✔Embryo


Alcoholics can have macrocytosis, does this mean that they have anemia?

- 🧠 ANSWER ✔✔No


A patient on a vegan diet is most at risk for which type of anemia and why?

- 🧠 ANSWER ✔✔Pernicious anemia due to a Vitamin B12 deficiency


A malnourished homeless patient comes into the hospital. He has scaling

at the corners of his mouth and painful ulcerations of the buccal mucosa.

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