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Immunization & Vaccination Final Exam (aPhA) (2025/2026) | Verified Masterfile

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This Immunization Liability & Influenza Vaccine Study Guide provides verified exam-style questions and answers designed for pharmacists, pharmacy technicians, and healthcare students preparing for immunization certification, PTCB, or board exams. It focuses on vaccine administration safety, influenza strains, pregnancy precautions, and CDC guidance.

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Immunization & Vaccination Final Exam (aPhA) (2025/2026) | Verified Masterfile



To reduce liability, pharmacists administering immunizations should take the following three steps:
✔️Receive specialized training and stay current with vaccine information updates; educate patients
about the benefits and risks of vaccinations; and emulate local standards of care.

Can technicians administer vaccinations? ✔️No

Pregnant women should not get what kind of vaccines? ✔️Live

Antigenic shifts produce ________ changes in type _____ antigens ✔️MAJOR; A

Antigenic drifts produce ________ changes in type ______ antigens ✔️minor; A and B

Children are more likely to get what type of influenza strain? ✔️B

Which type of influenza strain is responsible for pandemics? ✔️A

How long does immunity from the influenza vaccine typically last? ✔️6-8 months

If a baby is born prematurely, do you need to adjust their vaccination schedule to begin at their due
date? ✔️No, no adjustment--use actual birthday

True or false: you should never vaccinate somebody with a mild illness? (mild fever, upper respiratory
tract infection, otitis media, mild diarrhea) ✔️False--you can vaccinate people with mild illnesses

Will administering multiple vaccines on one day produce adverse effects? ✔️No

Can a pregnant pharmacist administer a live vaccine? ✔️Yes

Which publication does the CDC generally use to quickly notify providers of updates to vaccine
recommendations? ✔️MMWR.

What is the only flu vaccine approved for patients under 3 years old? ✔️Fluzone IIV

What is an example of mass screening? ✔️Providing vaccine information at a booth of a health fair.

What is an example of a procedure-based screening? ✔️Recommending vaccinations for a patient
undergoing a splenectomy.

What is an example of an occurrence-based screening? ✔️Providing hospital discharge counseling to a
patient.

What type of immunity targets pathogens that are circulating freely in body fluids, such as blood,
plasma, and lymph. ✔️Humoral immunity

What is the written vaccine update source also known as the "pink book?" ✔️Epidemiology and
Prevention of Vaccine-Preventable Diseases.

What form is required to receive compensation for giving a vaccination? ✔️CMS-1500.

,All Medicare Part B enrollees are covered for which two vaccines? ✔️Influenza and pneumococcal.

Robert is a 48-year-old pharmacist who is preparing to provide immunizations in his pharmacy for the
first time next fall. He has no documentation of receiving the hepatitis B vaccine and would like to be
vaccinated before administering vaccines in his practice. What is the recommended routine schedule for
vaccination against hepatitis B? ✔️0, 1, and 6 months.

Which of the following statements is true regarding administration of LAIV? ✔️Administer with the
patient's head tilted slightly backward.

Live vaccines are contraindicated in a patient who: ✔️Is immunosuppressed.

Which of the following diseases has been successfully eradicated worldwide through vaccination
efforts? ✔️Smallpox

David is a healthy 5-year-old boy who is scheduled to see his pediatrician for a checkup in July prior to
starting kindergarten. David's immunization record reveals that he has received the following vaccines:



3 doses of HepB

4 doses of PCV

2 doses of HepA

3 doses of IPV

3 doses of rotavirus

1 dose of MMR

4 doses of DTaP

1 dose of varicella

4 doses of Hib

Which vaccines should David receive at this visit? ✔️DTaP, IPV, MMR, and varicella.

Which of the following statements is true regarding how vaccines evoke an immune response? ✔️The
antigen in the vaccine activates B cells, which produce antigen-specific antibodies and memory cells.

According to ACIP recommendations, HZV is indicated for the prevention of herpes zoster in adults aged:
✔️60 years and older.

A health care provider who previously has not been vaccinated against hepatitis B is stuck by a
contaminated needle after administering an immunization to a hepatitis B positive patient during a
seasonal influenza clinic. In addition to hepatitis B vaccine, the health care provider also should receive
hepatitis B Immunoglobulin (HBIG) as postexposure prophylaxis because the HBIG provides: ✔️Prompt
immunity while the vaccine provides long-term protection.

, Which of the following vaccines containing tetanus, diphtheria, and/or pertussis would be most
appropriate for administration to a 69-year-old man who is preparing to travel to see his newborn
granddaughter next month? ✔️Tdap.

What is the FDA-licensed age range for the use of LAIV? ✔️2 to 49 years of age.

Which of the following best describes how to administer MMR vaccine to an adult patient weighing 155
lb? ✔️Inject subcutaneously at a 45° angle in the outer aspect of the upper arm.

Which vaccine does ACIP recommend for all college freshmen, living in dormitories, who have not been
previously vaccinated? ✔️MCV

Which of the following diseases are transmitted through mosquito bites? ✔️Yellow fever and Japanese
encephalitis.

If a patient is a candidate for revaccination with PPSV23, what is the ACIP-recommended interval
between doses of this vaccine? ✔️5 years

Which of the following key questions is important to as a patient before adminestering IIV? ✔️are you
sick today?

How often are the Healthy People targets for vaccination rates updated? Every *blank years* ✔️10 years

Which type of vaccine involves stimulation of B cells without the assistance of T helper cells? *blank*
polysaccharide *blank* ✔️pure vaccines

Which of the following documents must be given to every patient or patient's caregiver before
administration of a vaccine covered under the National Childhood Vaccine Injury Act (NCVIA)? ✔️VIS

RotaTeq (RV5) should be administered as a: *blank*-dose series to infants *blank,blank,blank* months
of age ✔️3 246

If a patient is a candidate for revaccination with PPSV23, what is the ACIP-recommended interval
between doses of this vaccine?

*blank years* ✔️5 years

After reconstitution, within what time frame must HZV be administered?

*blank mins* ✔️30 mins

Prior to the introduction of a vaccine, what was the leading cause of bacterial meningitis in children
younger than 5 years of age? *Haemophilus influenzae type BLANK* ✔️b

HealthMap Vaccine Finder is a free online tool that allows pharmacists to:

*List their vaccination BLANK so patients can find them when searching the website for nearby
immunizers.* ✔️services

Even though state laws may have specific mandates, how long should pharmacists maintain records of
immunizations?
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