NURS 611 EXAM 1 PATHO ACTUAL EXAM AND TEST BANK COMPLETE
155 QUESTIONS AND CORRECT DETAILED ANSWERS WITH
RATIONALES 2025/2026 GRADED A+
What is an aneuploid cell? - ......ANSWER........those that do not contain a multiple of 23
chromosomes
What is an example of an age-dependent penetrance? - ......ANSWER........Huntington
disease
What is demonstrated when twins age? what does this cause? - ......ANSWER........1- they
demonstrate increasing differences in methylation patterns of their DNA sequences
causing increased numbers in phenotype differences
What is Huntington's disease and what are the main features? - ......ANSWER........1-A
well-known autosomal dominant condition
2- progressive dementia and increasingly uncontrollable movements of the limbs
What is hyperplasia? - ......ANSWER........increase in the number of cells
What is hypertrophy? - ......ANSWER........increase in cell size
What is Incomplete Penetrance? - ......ANSWER........individuals who have a disease-
causing allele may not exhibit that expected phenotype at all, even though the allele and
the associated disease may be transmitted to the next generation
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What is ionizing radiation (IR)? - ......ANSWER........any form of radiation capable of
removing orbital electrons from atoms.
What is ionizing radiation emitted from? - ......ANSWER........x-rays, y-rays, alpha and beta
particles, subatomic particles such as neutrons, deuterons, protons, and prions
WEAR A LEAD APRON
What is metaplasia? - ......ANSWER........replacement of the cells
What are mitochondria responsible for? - ......ANSWER........cellular respiration, cellular
metabolism, and energy production
What is oncotic pressure heavily influenced by? - ......ANSWER........plasma proteins
What is oncotic pressure? - ......ANSWER........aka colloidal osmotic pressure- it is
pressure exerted by proteins, notably albumin, in the blood vessels plasma that tends to
pull water into the circulatory system
What is pathologic atrophy? - ......ANSWER........occurs because of decreases in workload,
use, pressure, blood supply, nutrition, and hormonal stimulation.
Ex: Shrinking of gonads in an adolescent pt in response to decreased hormonal
stimulation. and a pt immobilized in bed for a prolonged time
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What is physiologic atrophy? - ......ANSWER........occurs in early development. ex: thymus
gland during childhood
What is renin? - ......ANSWER........an enzyme secreted by the juxtaglomerular cells of the
kidney that promotes the production of the protein angiotensin.
What is sarcopenia? - ......ANSWER........muscular atrophy: degenerative skeletal muscle
loss
how fast it happens depends on nature/nurture
What is the #1 cause of cellular injury leading to necrosis (especially the kidney and heart)
- ......ANSWER........hypoxia
What is the #1 cause of hypoxia? - ......ANSWER........ischemia
What is the chance of a lifetime risk of developing breast cancer for women who inherit the
BRACA1 or BRACA2 gene? - ......ANSWER........50-80%
What is the compensatory response of resp acidosis? - ......ANSWER........increased HCO3
retention by kidneys