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ANCC Domain 1 Questions and Answers | Latest Version | 2025/2026 | Correct & Verified

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ANCC Domain 1 Questions and Answers | Latest Version | 2025/2026 | Correct & Verified What is the primary purpose of evidence-based practice in advanced nursing? A. To follow what senior staff recommend B. To apply research findings to improve patient outcomes C. To avoid legal responsibility D. To reduce patient education time Which of the following best describes translational research? A. Lab research with animals B. Moving scientific evidence into clinical practice C. Reviewing only published meta-analyses D. Conducting public health surveys What is the nurse’s first step in implementing an evidence-based protocol? A. Skip literature review B. Identify a clinical problem or question 2 C. Ask a peer what they would do D. Follow intuition Which research design is most appropriate to determine cause and effect? A. Qualitative interview B. Randomized controlled trial C. Literature review D. Case study What is the best resource to find current clinical guidelines? A. General news websites B. Peer-reviewed medical journals or databases like PubMed C. Social media D. Word-of-mouth from coworkers Which statement best defines clinical significance? A. The study was well-written B. The results have meaningful impact on patient care 3 C. The study got published in a big journal D. The sample size was small In EBP, what does the “P” in PICO stand for? A. Policy B. Patient, population, or problem C. Practice setting D. Peer-reviewed Why is it important to include patient preferences in

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ANCC Nursing Informatics
Certification Review Questions and
Answers | Latest Version | 2025/2026 |
Correct & Verified
What is the primary purpose of a clinical decision support system (CDSS)?

A. To replace nurses in patient care

B. To store patient billing information


✔✔C. To assist providers in making evidence-based clinical decisions


D. To generate patient satisfaction surveys




Which system is used to document direct patient care?

A. Payroll system


✔✔B. Electronic Health Record (EHR)


C. Administrative dashboard

D. Learning management system




Which role best describes a nurse who translates clinical needs into technical solutions?

A. Clinical instructor


1

,✔✔B. Nurse informaticist


C. Case manager

D. Unit clerk




Which informatics tool can track patient outcomes over time?

A. Fax machine

B. Medication cart


✔✔C. Clinical data registry


D. Whiteboard




What ensures the accuracy of electronic health data?

A. Allowing open edits


✔✔B. Data validation checks


C. Automatic deletion

D. Manual printouts




What does "interoperability" in healthcare informatics mean?

A. Storing data on local devices only


2

,✔✔B. Different systems exchanging and using health information


C. Using the same brand of computer

D. Sending records by mail




What is one benefit of using barcoding in medication administration?

A. Reduces time at bedside


✔✔B. Increases patient safety by reducing errors


C. Makes documentation optional

D. Eliminates the need for double-checks




Which federal law supports the adoption of EHRs?


✔✔A. HITECH Act


B. OSHA

C. EMTALA

D. ACA




Which format supports data exchange between different EHR systems?

A. PDF files


3

, ✔✔B. HL7 messaging standards


C. JPEG images

D. Microsoft Word templates




What does a data dictionary provide in a clinical information system?

A. Privacy settings

B. Medication labels


✔✔C. Standard definitions of data elements


D. Nurse shift schedules




Which user group benefits directly from dashboards that display clinical trends?

A. Cafeteria staff


✔✔B. Nurse managers and administrators


C. Visitors

D. Maintenance crew




Which is an example of structured data in the EHR?

A. A scanned physician note


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