RUBIN'S PATHOLOGY: CLINICOPATHOLOGIC FOUNDATIONS OF MEDICIN
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E 7TH EDITION
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DAVID S. STRAYER, EMANUEL RUBIN
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,TestuBankuRubin'suPathology:uClinicopathologicuFoundationsuofuMedicineu7thuEdition
TableuofuContents:
Chapteru1:uCelluAdaptation,uInjuryuanduDeath
Chapteru2:uInflammation
Chapteru3:uRepair,uRegenerationuanduFibrosis
Chapteru4:uImmunopathology
Chapteru5:uNeoplasia
Chapteru6:uDevelopmentaluanduGeneticuDiseases
Chapteru7:uHemodynamicuDisorders
Chapteru8:uEnvironmentaluanduNutritionaluPathology
Chapteru9:uInfectiousuanduParasiticuDiseases
SectionuII:uPathogenesisuofuSystemicuConditionsuExpandableusection
Chapteru10:uAging
Chapteru11:uSystemicuAutoimmuneuDiseases
Chapteru12:uSepsis
Chapteru13:uObesityuanduDiabetesuMellitus
Chapteru14:uTheuPathologyuofuPregnancy
Chapteru15:uTheuAmyloidoses
SectionuIII:uDiseasesuofuIndividualuOrganuSystemsExpandableusection
Chapteru16:uBlooduVessels
Chapteru17:uTheuHeart
Chapteru18:uTheuRespiratoryuSystem
Chapteru19:uTheuGastrointestinaluTract
Chapteru20:uTheuLiveruanduBiliaryuSystem
Chapteru21:uTheuPancreas
Chapteru22:uTheuKidney
Chapteru23:uTheuLoweruUrinaryuTractuanduMaleuReproductiveuSystem
Chapteru24:uTheuFemaleuReproductiveuSystemuanduPeritoneum
Chapteru25:uTheuBreast
Chapteru26:uHematopathology
Chapteru27:uTheuEndocrineuSystem
Chapteru28:uTheuSkin
Chapteru29:uTheuHeaduanduNeck
Chapteru30:uBones,uJointsuanduSoftuTissue
Chapteru31:uSkeletaluMuscleuanduPeripheraluNervousuSystem
Chapteru32:uTheuCentraluNervousuSystem
Chapteru33:uTheuEye
Chapteru34:uForensicuPathology
,Rubin'suPathology:uClinicopathologicuFoundationsuofuM
edicineChapteru1:uCelluAdaptation,uInjuryuanduDeath
Ischemiauanduotherutoxicuinjuriesuincreaseutheuaccumulationuofuintracellularucalciumuasuauresult
1. of:
A) releaseuofustoreducalciumufromutheumitochondria.
B) improveduintracellularuvolumeuregulation.
C) decreaseduinfluxuacrossutheucellumembrane.
D) attractionuofucalciumutoufattyuinfiltrates.
Theupatientuisufoundutouhaveuliverudisease,uresultinguinutheuremovaluofuaulobeuofuhisuliver.
2. Adaptationutoutheureducedusizeuofutheuliveruleadsutou_ ofutheuremaininguliverucells.
A) metaplasia
B) organuatrophy
C) compensatoryuhyperplasia
D) physiologicuhypertrophy
Aupersonueatingupeanutsustartsuchokinguanducollapses.uHisuairwayuobstructionuisupartiallyucleared
,ubutuheuremainsuhypoxicuuntiluheureachesutheuhospital.uTheuprolongeducelluhypoxia
3. causeduaucerebraluinfarctionuanduresulting _uinutheubrain.
A) caspaseuactivation
B) coagulationunecrosis
C) rapiduphagocytosis
D) proteinup53udeficiency
Bacteriauanduvirusesucauseucelludamageuby ,uwhichuisuuniqueufromutheuintracellular
4. damageucausedubyuotheruinjuriousuagents.
A) disruptingutheusodium/potassiumuATPaseupump
B) interruptinguoxidativeumetabolismuprocesses
C) replicatinguanduproducingucontinueduinjury
D) decreasinguproteinusynthesisuandufunction
Theupatientuhasuauprolongeduinterruptionuinuarterialublooduflowutouhisuleftukidney,ucausing
5. hypoxicucelluinjuryuandutheureleaseuofufreeuradicals.uFreeuradicalsudamageucellsuby:
A) destroyinguphospholipidsuinutheucellumembrane.
B) alteringutheuimmuneuresponseuofutheucell.
C) disruptingucalciumustorageuinutheucell.
D) inactivationuofuenzymesuandumitochondria.
, 6. Injureducellsuhaveuimpaireduflowuofusubstancesuthroughutheucellumembraneuasuauresultuof:
A) increasedufatuload.
B) alteredupermeability.
C) altereduglucoseuutilization.
D) increasedusurfaceureceptors.
7. Reversibleuadaptiveuintracellularuresponsesuareuinitiateduby:
A) stimulusuoverload.
B) geneticumutations.
C) chemicalumessengers.
D) mitochondrialuDNA.
8. Injureducellsubecomeuveryuswollenuasuauresultuof:
A) increaseducelluproteinusynthesis.
B) altereducelluvolumeuregulation.
C) passiveuentryuofupotassiumuintoutheucell.
D) blebuformationuinutheuplasmaumembrane.
Audiabeticupatientuhasuimpairedusensation,ucirculation,uanduoxygenationuofuhisufeet.uHeustepsuonuau
pieceuofuglass,utheuwoundudoesunotuheal,uandutheuareautissueubecomesunecrotic.uTheunecrotic
9. celludeathuisucharacterizeduby:
A) rapiduapoptosis.
B) cellularurupture.
C) shrinkageuanducollapse.
D) chronicuinflammation.
Au99-year-olduwomanuhasuexperiencedutheudeclineuofucellufunctionuassociateduwithuage.uA
10. groupuofutheoriesuofucellularuagingufocusuonuprogrammed:
A) changesuwithugeneticuinfluences.
B) eliminationuofucellureceptorusites.
C) insufficientutelomeraseuenzyme.
D) DNAumutationuorufaultyurepair.
Anu89-year-
oldufemaleupatientuhasuexperiencedusignificantudecreasesuinuherumobilityuandustaminauduringuau3
-
weekuhospitalustayuforutheutreatmentuofuaufemoraluheadufracture.uWhichuofutheufollowinguphenom
enaumostulikelyuaccountsuforutheupatientsudecreaseuinumuscleufunction
11. thatuunderliesuherureducedumobility?
A) Impairedumuscleucellumetabolismuresultingufromumetaplasia
B) Dysplasiauasuauconsequenceuofuinflammationuduringuboneuremodeling
C) Disuseuatrophyuofumuscleu cellsuduringuauprolongeduperioduofuimmobility