* tumor in adrenal gland
HYPERALDOSTERONISM
• Excessive aldosterone
• Cirrhosis, nephrotic syndrome, HF, HTN (secondary)
SIGNS & SYMPTOMS * polyuna
• Hypernatremia
Aphority ↑ Na
=
• HTN
• Hypokalemia * turnor -
>
advenolectomy
* assess Na JVD + weigh
• Fatigue/weakness daily
, ,
• Numbness
• HA
TREATMENT
• Spironolactone K sparring &
-
CONGENTIAL ADRENAL HYPERPLASIA
↓ Cortisol & ↓
• Females have male characteristics
aldosterone
*to many o Muscle bulk, body hair & deep voice, facial hair
androgens • Males – darkening of skin a go bald
* synthetic • Decreased cortisol & increased male hormones
!
hounones given
• Pituitary keeps producing ATCH always near
• Life-long corticosteroids (glucocorticoids, prednisone)X just
never stop !
• @ risk for adrenal crisis d/t cortisol
ADRENAL CORTEX
• Makes corticoids
o Glucocorticoid & cortisol (sugar)
• Produce:
o Cortisol – suppresses inflammation; regulates blood
pressure; increases blood sugar; decreases bone
formation
, o Aldosterone – absorb more sodium into bloodstream
release potassium
o Androgen
* any immuno HYPOALDOSTERONISM
compromised
• Shortage (deficiency) or impaired fxn of hormone called
disease can
aldosterone. Low sodium (hyponatremia), too much
cause !
potassium (hyperkalemia), metabolic acidosis
• Dark pigmentation – high ACTH
SIGNS & SYMPTOMS D Irreg rhythms
o Hypoglycemia
postural hypotension
o Hyponatremia * dit
Ateach daily blood glucose monitoring
o Hypotension hypoglycemia
o Hyperkalemia
CARE * loopIthiazide diuretic &IVF(0 9 % NaCK) .
* fall precautions
o Glucocorticoids – lifetime hormone replacement
-
Findrocortisone
di+ ↓ It
↓) ↳ Watch for o Encourage foods w sodium
+ waveso Change positions slowly
put on high
e monitor ADDISIONS DISEASE
• Low cortisol
DIAGNOSIS
o Early AM cortisol & plasma ACTH; abnormal labs
(glucose, Sodium, potassium, WBC)
SIGNS & SYMPTOMS
know An woning o Decreased sodium & blood glucose (may lead to
when Nar
dehydration)
o Increased potassium
o Hypotension
o Increased WBC
o Muscle weakness
o Anorexia
o Dark pigmentation
HYPERALDOSTERONISM
• Excessive aldosterone
• Cirrhosis, nephrotic syndrome, HF, HTN (secondary)
SIGNS & SYMPTOMS * polyuna
• Hypernatremia
Aphority ↑ Na
=
• HTN
• Hypokalemia * turnor -
>
advenolectomy
* assess Na JVD + weigh
• Fatigue/weakness daily
, ,
• Numbness
• HA
TREATMENT
• Spironolactone K sparring &
-
CONGENTIAL ADRENAL HYPERPLASIA
↓ Cortisol & ↓
• Females have male characteristics
aldosterone
*to many o Muscle bulk, body hair & deep voice, facial hair
androgens • Males – darkening of skin a go bald
* synthetic • Decreased cortisol & increased male hormones
!
hounones given
• Pituitary keeps producing ATCH always near
• Life-long corticosteroids (glucocorticoids, prednisone)X just
never stop !
• @ risk for adrenal crisis d/t cortisol
ADRENAL CORTEX
• Makes corticoids
o Glucocorticoid & cortisol (sugar)
• Produce:
o Cortisol – suppresses inflammation; regulates blood
pressure; increases blood sugar; decreases bone
formation
, o Aldosterone – absorb more sodium into bloodstream
release potassium
o Androgen
* any immuno HYPOALDOSTERONISM
compromised
• Shortage (deficiency) or impaired fxn of hormone called
disease can
aldosterone. Low sodium (hyponatremia), too much
cause !
potassium (hyperkalemia), metabolic acidosis
• Dark pigmentation – high ACTH
SIGNS & SYMPTOMS D Irreg rhythms
o Hypoglycemia
postural hypotension
o Hyponatremia * dit
Ateach daily blood glucose monitoring
o Hypotension hypoglycemia
o Hyperkalemia
CARE * loopIthiazide diuretic &IVF(0 9 % NaCK) .
* fall precautions
o Glucocorticoids – lifetime hormone replacement
-
Findrocortisone
di+ ↓ It
↓) ↳ Watch for o Encourage foods w sodium
+ waveso Change positions slowly
put on high
e monitor ADDISIONS DISEASE
• Low cortisol
DIAGNOSIS
o Early AM cortisol & plasma ACTH; abnormal labs
(glucose, Sodium, potassium, WBC)
SIGNS & SYMPTOMS
know An woning o Decreased sodium & blood glucose (may lead to
when Nar
dehydration)
o Increased potassium
o Hypotension
o Increased WBC
o Muscle weakness
o Anorexia
o Dark pigmentation
