LATEST UPDATE WGU D027 ADVANCED PATHOPHARMACOLOGICAL FOUNDATIONS (ACTUAL) QUESTIONS AND ANSWERS

LATEST UPDATE WGU D027 ADVANCED
PATHOPHARMACOLOGICAL
FOUNDATIONS (ACTUAL 2025-2026)
QUESTIONS AND ANSWERS
Why are aminosalicylates used for in patients with Crohn's
A A A A A A A A A



disease? - ---answers A- Reduce inflammation
A A A




What are some aminosalicylates that are used to treat Crohn's
A A A A A A A A A A



disease? - ---answers - Sulfasalazine
A A A




- Mesalamine


Why are corticosteroids used for in patients with Crohn's
A A A A A A A A A



disease? - ---answers A - Reduce inflammation
A A A




- Only used if aminosalicylates are not effective during an
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exacerbation


What are the sickle cell and parent traits? - ---answers
A A A A A A A A A -
Children who have, 25%
A A A A




- Children who do not have and are not carriers, 25%
A A A A A A A A A




- Children who are carriers, 50% A A A A




What is Huntington's disease? - ---answers
A A A A A -
Autosomal dominant disorder
A A A




- A person only needs one copy of each of the affected gene to d
A A A A A A A A A A A A A



evelop the disorder
A A




- Each child has a 50% chance of inheriting the gene that
A A A A A A A A A A A



causes the disease
A A

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THOPHARMACOLOGICAL FOUNDATIONS ( A A




ACTUAL 2024-2025) QUESTIONS AND ANSWERS A A A A



- Leads to progressive degeneration of nerve cells that affects
A A A A A A A A A



movement, cognitive functions, and emotions A A A A




What is an example of an autosommal dominant disorder? - --
A A A A A A A A A A



-answers - Huntington's disease A A




What is an example of an autosomal recessive disorder? - ---
A A A A A A A A A A



answers
A - Cystic fibrosis A A




What is cystic fibrosis? - ---answers
A A A A A -
Autosomal recessive disorder
A A A




- The lungs and the digestive system get clogged with mucus
A A A A A A A A A




- Affects the pancreas causing secretions in the lungs
A A A A A A A




- Caused by CTFR mutation A A A




What are some ways that cystic fibrosis affects the different
A A A A A A A A A A



parts in the body? - ---answers
A A - A A A



ALungs: block airways causing inflammation and increasing
A A A A A A A



the risk of infection, pulmonary hypertension, and tissue da
A A A A A A A A



mage
- Digestive tract: block secretion of digestive enzymes from th
A A A A A A A A



e pancreases leading to malabsorption and malnutrition, can al
A A A A A A A A



so lead to chronic pancreatitis
A A A A

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THOPHARMACOLOGICAL FOUNDATIONS ( A A




ACTUAL 2024-2025) QUESTIONS AND ANSWERS A A A A



- Liver: blockage of the bile ducts can interfere with the liver's
A A A A A A A A A A A



ability to clear toxins from the blood leading to scarring, gallst
A A A A A A A A A A



ones, and cirrhosis
A A




- Reproductive system: structural problems that renders the A A A A A A A



majority of men with this disorder to be infectable
A A A A A A A A




- Endocrine system: blockage of insulin- A A A A



producing cells on the pancreas (islets of Langerhans) can l
A A A A A A A A A



ead to type of diabetes that has characteristics of both type 1
A A A A A A A A A A A



Aand type 2 diabetes
A A A




What are some symptoms of patients with cystic fibrosis? - ---
A A A A A A A A A A



answers
A - Very salty-tasting skin A A A




- Postnasal drip, sinusitis A A




- Shortness of breath A A




- Repeated lung infections A A




- Foul-smelling, bulky greasy stools A A A




- Poor growth A




- Male infertility A




What are some diagnostic tests used to diagnose cystic fibros
A A A A A A A A A



is? - ---answers
A A -
ASweat test (measures the amount of chloride in sweat)
A A A A A A A A

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THOPHARMACOLOGICAL FOUNDATIONS ( A A




ACTUAL 2024-2025) QUESTIONS AND ANSWERS A A A A



- Genetic test (detects chromosomal mutations associated with
A A A A A A A



the disease)
A




What is an example of x-linked dominant disorder? - ---
A A A A A A A A A



answers
A -
Duchenne muscular dystrophy inheritance (DMD)
A A A A A




- Color blindness A




What is Duchenne Muscular Dystrophy? ----- answers
A A A A - X-A



linked dominant disorderA A




- Until recently, children with this order did not live beyond t
A A A A A A A A A A



heir teens A




- Life expectancy now 30's and some into their 40's to 50's
A A A A A A A A A A




- Affects the muscles, leading to muscle wasting that worsens
A A A A A A A A A



over time A




- Almost always affects boys and symptoms being early in
A A A A A A A A A



childhood


What are some signs and symptoms in patients with Duchenn
A A A A A A A A A



e Muscular Dystrophy? - ---answers ------------------ Difficulty
A A A A



standing up, walking, and climbing stairs
A A A A A




- May have heart and lung problems
A A A A A




- Scoliosis