, Chapter 01: General Principles of Pharmacology
Ford: Introductory Clinical Pharmacology 12th Edition
1. After teaching a group of students about the basics of pharmacology, the
students will be able to choose which aspect as the most critical to
remember?
A) Drug name
B) Drug class
C) Drug action
D) Drug source
Answer: C
Rationale: Pharmacology is the study of drugs and its action on living
organisms. Thus, an essential aspect of pharmacology is drug action. An
understanding of the drug name, drug class, and drug source is important,
but the most critical aspect related to pharmacology is how the drug acts
in the body.
Question Format: Multiple
Choice Chapter: 1
Learning Objective: 1
Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological
Therapies Integrated Process: Teaching/Learning
Reference: p. 3, Introduction
2. A nurse suspects the client had an adverse reaction to a prescribed
medication due to an interaction with an unreported over-the-counter
supplement. Which action by the nurse will best assist in preventing
future similar incidents?
A) File a report with MedWatch
B) File a report with the State Board of Nursing
C) Instruct the client to avoid combining medications in the future
D) Document the incident and report it to the health care provider
Answer: A
Rationale: Nurses play an important role in monitoring for adverse
reactions. Therefore, it is important to submit reports, even if there is
uncertainty about the cause–effect relationship. The FDA protects the
identity of those who voluntarily report adverse reactions.
Question Format: Multiple
Choice Chapter: 1
, Client Needs: Safe and Effective Care Environment: Safety and
InfectionControl
Integrated Process: Clinical Problem-solving Process (Nursing
Process) Reference: p. 7, Box 1.1 MedWatch and Reporting
Adverse Events
3. A nurse is assessing a client and notes the client has developed swelling
of the eyelids and lips after administration of a prescribed medication.
What does the nurse interpret this finding to specifically indicate?
A) Mild allergic reaction
B) Anaphylactic shock
C) Angioedema
D) Drug idiosyncrasy
Answer: C
Rationale: Angioedema is a type of allergic drug reaction manifested by
the collection of fluid in the subcutaneous tissues, most commonly
affecting the eyelids, lips, mouth, and throat. Allergic reactions can be
manifested by a wide range of signs and symptoms such as itching,
rashes, and hives. Anaphylactic shock is a serious allergic reaction that
requires immediate medical attention. Drug idiosyncrasy describes any
unusual or abnormal reaction to a drug, one that is different from the one
normally expected.
Question Format: Multiple
Choice Chapter: 1
Learning Objective: 5
Cognitive Level: Apply
Client Needs: Physiological Integrity: Reduction of Risk Potential
Integrated Process: Clinical Problem-solving Process (Nursing
Process) Reference: p. 12, Allergic Drug Reactions
4. The nurse is preparing to teach a client about a new drug which is in the
fourth phase of development. Which activity will the nurse explain best
illustrates this phase?
A) Health care providers report adverse effects to FDA.
B) Healthy volunteers are involved in the test.
C) In vitro tests are performed using human cells.
D) The drug is given to clients with the disease.
Answer: A
, Rationale: The postmarketing surveillance phase of drug development
encourages health care professionals to report adverse effects of drugs to
the FDA using MedWatch. Phase 1 of clinical testing involves 20 to 100
healthy volunteers. In vitro testing of the drug on human or animal cells is
done in the pre-FDA phase. In Phase 2 of clinical testing, the drug is given to
clients with the disease for which the drug is manufactured.
Question Format: Multiple
Choice Chapter: 1
Learning Objective: 4
Cognitive Level: Apply
Client Needs: Health Promotion and
Maintenance Integrated Process:
Teaching/Learning Reference: p. 7, Concept
Mastery Alert
5. A nurse is assessing a pregnant client who admits to having a
cocaine addiction. Which condition of the baby after birth should the
nurse explain and preparethe client for?
A) Diabetes
B) Hypertension
C) Addiction to drugs
D) CNS defects
Answer: C
Rationale: The nurse informs the client that children born to mothers
using addictive drugs are often born with an addiction to the drug.
Children born to mothers who are addicted to cocaine are not known to
be born with diabetes, CNS defects, or hypertension.
Question Format: Multiple
Choice Chapter: 1
Learning Objective: 6
Cognitive Level: Apply
Client Needs: Health Promotion and
Maintenance Integrated Process:
Teaching/Learning
Reference: p. 11, Drug Use, Pregnancy, and Lactation
6. A client arrives at the health care clinic and reports taking several pills
for a headache and severe cough without relief. Which adverse effect
should the nurse be aware may develop from this combination?
A) Gastrointestinal bleeding
B) Breathing difficulties
C) Liver damage
D) Anaphylaxis
Ford: Introductory Clinical Pharmacology 12th Edition
1. After teaching a group of students about the basics of pharmacology, the
students will be able to choose which aspect as the most critical to
remember?
A) Drug name
B) Drug class
C) Drug action
D) Drug source
Answer: C
Rationale: Pharmacology is the study of drugs and its action on living
organisms. Thus, an essential aspect of pharmacology is drug action. An
understanding of the drug name, drug class, and drug source is important,
but the most critical aspect related to pharmacology is how the drug acts
in the body.
Question Format: Multiple
Choice Chapter: 1
Learning Objective: 1
Cognitive Level: Apply
Client Needs: Physiological Integrity: Pharmacological
Therapies Integrated Process: Teaching/Learning
Reference: p. 3, Introduction
2. A nurse suspects the client had an adverse reaction to a prescribed
medication due to an interaction with an unreported over-the-counter
supplement. Which action by the nurse will best assist in preventing
future similar incidents?
A) File a report with MedWatch
B) File a report with the State Board of Nursing
C) Instruct the client to avoid combining medications in the future
D) Document the incident and report it to the health care provider
Answer: A
Rationale: Nurses play an important role in monitoring for adverse
reactions. Therefore, it is important to submit reports, even if there is
uncertainty about the cause–effect relationship. The FDA protects the
identity of those who voluntarily report adverse reactions.
Question Format: Multiple
Choice Chapter: 1
, Client Needs: Safe and Effective Care Environment: Safety and
InfectionControl
Integrated Process: Clinical Problem-solving Process (Nursing
Process) Reference: p. 7, Box 1.1 MedWatch and Reporting
Adverse Events
3. A nurse is assessing a client and notes the client has developed swelling
of the eyelids and lips after administration of a prescribed medication.
What does the nurse interpret this finding to specifically indicate?
A) Mild allergic reaction
B) Anaphylactic shock
C) Angioedema
D) Drug idiosyncrasy
Answer: C
Rationale: Angioedema is a type of allergic drug reaction manifested by
the collection of fluid in the subcutaneous tissues, most commonly
affecting the eyelids, lips, mouth, and throat. Allergic reactions can be
manifested by a wide range of signs and symptoms such as itching,
rashes, and hives. Anaphylactic shock is a serious allergic reaction that
requires immediate medical attention. Drug idiosyncrasy describes any
unusual or abnormal reaction to a drug, one that is different from the one
normally expected.
Question Format: Multiple
Choice Chapter: 1
Learning Objective: 5
Cognitive Level: Apply
Client Needs: Physiological Integrity: Reduction of Risk Potential
Integrated Process: Clinical Problem-solving Process (Nursing
Process) Reference: p. 12, Allergic Drug Reactions
4. The nurse is preparing to teach a client about a new drug which is in the
fourth phase of development. Which activity will the nurse explain best
illustrates this phase?
A) Health care providers report adverse effects to FDA.
B) Healthy volunteers are involved in the test.
C) In vitro tests are performed using human cells.
D) The drug is given to clients with the disease.
Answer: A
, Rationale: The postmarketing surveillance phase of drug development
encourages health care professionals to report adverse effects of drugs to
the FDA using MedWatch. Phase 1 of clinical testing involves 20 to 100
healthy volunteers. In vitro testing of the drug on human or animal cells is
done in the pre-FDA phase. In Phase 2 of clinical testing, the drug is given to
clients with the disease for which the drug is manufactured.
Question Format: Multiple
Choice Chapter: 1
Learning Objective: 4
Cognitive Level: Apply
Client Needs: Health Promotion and
Maintenance Integrated Process:
Teaching/Learning Reference: p. 7, Concept
Mastery Alert
5. A nurse is assessing a pregnant client who admits to having a
cocaine addiction. Which condition of the baby after birth should the
nurse explain and preparethe client for?
A) Diabetes
B) Hypertension
C) Addiction to drugs
D) CNS defects
Answer: C
Rationale: The nurse informs the client that children born to mothers
using addictive drugs are often born with an addiction to the drug.
Children born to mothers who are addicted to cocaine are not known to
be born with diabetes, CNS defects, or hypertension.
Question Format: Multiple
Choice Chapter: 1
Learning Objective: 6
Cognitive Level: Apply
Client Needs: Health Promotion and
Maintenance Integrated Process:
Teaching/Learning
Reference: p. 11, Drug Use, Pregnancy, and Lactation
6. A client arrives at the health care clinic and reports taking several pills
for a headache and severe cough without relief. Which adverse effect
should the nurse be aware may develop from this combination?
A) Gastrointestinal bleeding
B) Breathing difficulties
C) Liver damage
D) Anaphylaxis
