NURS 6630 Psychopharmacology Midterm Study
Guide questions with correct verified detailed
answers (Walden University) latest updated
version 2025
TCAs inhibitory effects on Alpha 1 receptors results in this side effect:
--- correct precise answer ---orthostatic hypotension
This class of antidepressants is especially cardiotoxic and may cause
arrhythmias and prolonged QT interval: --- correct precise answer ---
TCAs
Treatment of cardiotoxicity from TCAs: --- correct precise answer ---
Sodium Bicarbonate
The three most common causes of death from TCAs (The 3C's): ---
correct precise answer ---Convulsion, Coma, and Cardiotoxicity
This class of antidepressants inhibits Cytochrome P450 Enzymes: ---
correct precise answer ---TCAs
,Combining these substances with Cytochrome P450 enzyme inhibitors
can result in severe respiratory depression and death due to toxic
levels: --- correct precise answer ---Ethanol and sedative hypnotics
(benzos)
These two neuron types have abundant Alpha 2 receptors: --- correct
precise answer ---Noradrenergic and Serotonergic
When stimulated Alpha 2 receptors inhibit the activity of the
presynaptic neuron and decrease the release of these two
neurotransmitters: --- correct precise answer ---Norepinephrine and
Serotonin
Six common Atypical Antidepressants used for individuals that did not
respond to other antidepressants: --- correct precise answer ---
mirtazapine, trazadone, nefazodone, vilazodone, vortioxetine,
bupropion
This antidepressant effects Alpha 2 receptors, 5-HT2A receptors, 5-
HT3A receptors, and Histamine H1 receptors: --- correct precise
answer ---mirtazapine
,The primary antidepressant action of this drug comes from inhibition
of the Alpha 2 receptors, which reduces the inhibition of the synaptic
neuron, and thus increases Norepinephrine and Serotonin release ---
correct precise answer ---mirtazapine
As a Serotonin Antagonist, this Atypical Antidepressant blocks 5-HT2A
and 5-HT3A receptors to increase the amount of Serotonin available to
bind to 5-HT1A receptors which are more strongly linked to
depression: --- correct precise answer ---mirtazapine
Mirtazapine's inhibition of 5-HT3A receptors reduces: --- correct
precise answer ---nausea and vomiting
Mirtazapine's inhibition of Histamine H1 receptors causes: --- correct
precise answer ---sedation (could be desirable side effect for
depressed individuals with insomnia)
For depressed individuals with anorexia, increased appetite and
weight gain, are possibly beneficial side effects of this Atypical
Antidepressant: --- correct precise answer ---mirtazapine
As Serotonin Antagonists, these two Atypical Antidepressants block 5-
HT2A receptors so that more Serotonin is available to bind to 5-HT1A
, receptors which are more strongly linked to depression: --- correct
precise answer ---trazodone and nefazodone
In addition to inhibition of 5-HT2A receptors, these two Atypical
Antidepressants increase levels of Serotonin in the synaptic cleft
through weak inhibition of Serotonin reuptake transporters: ---
correct precise answer ---trazodone and nefazodone
These two Atypical Antidepressants are strong H1 receptor inhibitors,
and therefore commonly used to treat insomnia: --- correct precise
answer ---trazodone and nefazodone
These two Atypical Antidepressants may cause orthostatic
hypotension and priapism through Alpha-1 receptor inhibition: ---
correct precise answer ---trazodone and nefazodone
In rare cases, this Atypical Antidepressant is known to cause severe
liver damage: --- correct precise answer ---nefazodone
Similar to SSRIs, these two Atypical Antidepressants are strong
inhibitors of Serotonin reuptake transporters on the presynaptic
neuron: --- correct precise answer ---vilazodone and vortioxetine
Guide questions with correct verified detailed
answers (Walden University) latest updated
version 2025
TCAs inhibitory effects on Alpha 1 receptors results in this side effect:
--- correct precise answer ---orthostatic hypotension
This class of antidepressants is especially cardiotoxic and may cause
arrhythmias and prolonged QT interval: --- correct precise answer ---
TCAs
Treatment of cardiotoxicity from TCAs: --- correct precise answer ---
Sodium Bicarbonate
The three most common causes of death from TCAs (The 3C's): ---
correct precise answer ---Convulsion, Coma, and Cardiotoxicity
This class of antidepressants inhibits Cytochrome P450 Enzymes: ---
correct precise answer ---TCAs
,Combining these substances with Cytochrome P450 enzyme inhibitors
can result in severe respiratory depression and death due to toxic
levels: --- correct precise answer ---Ethanol and sedative hypnotics
(benzos)
These two neuron types have abundant Alpha 2 receptors: --- correct
precise answer ---Noradrenergic and Serotonergic
When stimulated Alpha 2 receptors inhibit the activity of the
presynaptic neuron and decrease the release of these two
neurotransmitters: --- correct precise answer ---Norepinephrine and
Serotonin
Six common Atypical Antidepressants used for individuals that did not
respond to other antidepressants: --- correct precise answer ---
mirtazapine, trazadone, nefazodone, vilazodone, vortioxetine,
bupropion
This antidepressant effects Alpha 2 receptors, 5-HT2A receptors, 5-
HT3A receptors, and Histamine H1 receptors: --- correct precise
answer ---mirtazapine
,The primary antidepressant action of this drug comes from inhibition
of the Alpha 2 receptors, which reduces the inhibition of the synaptic
neuron, and thus increases Norepinephrine and Serotonin release ---
correct precise answer ---mirtazapine
As a Serotonin Antagonist, this Atypical Antidepressant blocks 5-HT2A
and 5-HT3A receptors to increase the amount of Serotonin available to
bind to 5-HT1A receptors which are more strongly linked to
depression: --- correct precise answer ---mirtazapine
Mirtazapine's inhibition of 5-HT3A receptors reduces: --- correct
precise answer ---nausea and vomiting
Mirtazapine's inhibition of Histamine H1 receptors causes: --- correct
precise answer ---sedation (could be desirable side effect for
depressed individuals with insomnia)
For depressed individuals with anorexia, increased appetite and
weight gain, are possibly beneficial side effects of this Atypical
Antidepressant: --- correct precise answer ---mirtazapine
As Serotonin Antagonists, these two Atypical Antidepressants block 5-
HT2A receptors so that more Serotonin is available to bind to 5-HT1A
, receptors which are more strongly linked to depression: --- correct
precise answer ---trazodone and nefazodone
In addition to inhibition of 5-HT2A receptors, these two Atypical
Antidepressants increase levels of Serotonin in the synaptic cleft
through weak inhibition of Serotonin reuptake transporters: ---
correct precise answer ---trazodone and nefazodone
These two Atypical Antidepressants are strong H1 receptor inhibitors,
and therefore commonly used to treat insomnia: --- correct precise
answer ---trazodone and nefazodone
These two Atypical Antidepressants may cause orthostatic
hypotension and priapism through Alpha-1 receptor inhibition: ---
correct precise answer ---trazodone and nefazodone
In rare cases, this Atypical Antidepressant is known to cause severe
liver damage: --- correct precise answer ---nefazodone
Similar to SSRIs, these two Atypical Antidepressants are strong
inhibitors of Serotonin reuptake transporters on the presynaptic
neuron: --- correct precise answer ---vilazodone and vortioxetine
