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NR 507 Pathophysiology – Midterm Exam – Chamberlain University – 2024/2025 – Questions with 100% Accurate Answers

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This document presents a complete and verified set of midterm exam questions and answers for NR 507: Advanced Pathophysiology at Chamberlain University, tailored to the 2025 curriculum. It includes core topics such as cellular adaptation and injury, inflammation, immunity, genetic and epigenetic influences, and system-based disorders including cardiovascular, neurological, and endocrine conditions. Perfect for nurse practitioner students, this resource supports in-depth understanding and confident midterm preparation.

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NR 507 PATHOPHYSIOLGY MIDTERM
QUESTIONS WITH 100% ACCURATE ANSWERS

S1 - Accurate answers First heart sound, closure of mital and tricuspid valves in systole

S2 - Accurate answers Second heart sound, closure of aortic and pulmonica valves in diastole

Preload - Accurate answers Diastolic filling with venous blood

Contractility - Accurate answers Systolic ejection

Afterload - Accurate answers Resistance to systolic ejection

Equation for cardiac output - Accurate answers stroke volume x heart rate

Sustained tachycardia causes ___ - Accurate answers Decreased stroke volume

Ischemia, acidosis and cardiomyopathy cause___ - Accurate answers Decreased contractility

HTN, pulmonary disease and aortic valve damage cause ___ - Accurate answers Increased
afterload

What is the most immediate effect on afterload? - Accurate answers HTN

Hemorrhage and decreased volume decreases ___and ___ - Accurate answers Preload and
afterload

Increased preload increases ___ - Accurate answers Stroke volume

Right sided HF is also called ___ - Accurate answers Cor pulmonale

Cor pulmonale causes ___ and is caused by ___ - Accurate answers Enlargement of RV, pulmonary
HTN from chronic lung disease

5 causes of lung disease leading to cor pulmonale? - Accurate answers COPD, PE, pulmonary
fibrosis, OSA, myasthenia gravis, polio

4 causes of heart failure - Accurate answers CAD, HTN, cardiomyopathy, faulty valves

4 events that lead to HF - Accurate answers HTN, increased LV preload, increased LA preload,
pulmonary edema

Define ventilation - Accurate answers The ability to inhale and exhale air

, Define perfision - Accurate answers The ability of lungs and tissues to perform gas exchange

Intrinsic asthma - Accurate answers Internal trigger (anxiety)

Extrinsic asthma - Accurate answers External trigger, allergic response mediated by IgE

Asthma s/s - Accurate answers Wheezing, chest tightness, SOB

Asthma treatment - 3 classes/medications - Accurate answers Beta 2 agonists-albuterol,
anticholinergics for bronchodilation-ipratropium, oral steroids to reduce inflammation-prednisone

Chronic bronchitis s/s - Accurate answers Productive cough, dyspnea, wheezing, rhonchi, cyanosis

Where does damage occur in bronchitis? - Accurate answers Airway

What is the lamina propria? - Accurate answers Thin connective tissue, forms moist linings/mucous
membranes

Where are inflammatory cells activated in chronic bronchitis? - Accurate answers Lamina propria

What plays a significant role in chronic brnonchitis development? - Accurate answers Lamina
propria

What is a long term effect of COPD? (Blood) - Accurate answers Secondary polycythemia

S/S in polycythemia secondary to COPD - Accurate answers Increased HCT by RBC compensation,
can lead to blood clot

What is a long term effect of COPD? (lungs) - Accurate answers Alveolar hyperinflation, decreased
ability to exhale, air trapping

Where is erythropoietin produced? - Accurate answers Kidneys

Where is angiotensin converting enzyme (ACE) produced? - Accurate answers Lungs

Where is angiotensinogen synthesized? - Accurate answers Liver

What is the role of ACE? - Accurate answers Activate angiotensin I to form angiotensin II

What is the most important component of filtration? - Accurate answers Blood (hydrostatic)
pressure

Define reabsorption - Accurate answers Movement of content from glomerular filtrate to blood

Define excretion - Accurate answers Elimination from the body

Define secretion - Accurate answers Movement of contents from blood to the nephron
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