CRNA Interview Medications|Questions With Correct
Answers|Verified
Norepinephrine Mechanism of Action - ✅Alpha-adrenergic activity: peripheral vasoconstriction
Beta-adrenergic activity: inotropic stimulation of the heart and coronary artery vasodilation
Norepinephrine Common Uses - ✅First line of shock
Norepinephrine Typical Dosing - ✅0.04-0.3 mcg/kg/min
Norepinephrine Onset/Duration of Action - ✅Onset: Immediate
Duration: 1-2 minutes
Norepinephrine Side Effects - ✅Arrhythmias
Severe peripheral vasoconstriction leading to tissue death and limb ischemia
Vasopressin Mechanism of Action - ✅1. Direct stimulation of smooth muscle V1 receptors:
vasoconstriction
2. Acts on V2 receptors in kidneys: water reabsorption
Vasopressin Common Uses - ✅Used with other vasopressors like Levophed
Also used in GI bleeding and Diabetes Insipidus
Vasopressin Typical Dosing - ✅0.03 units/min (TICU does not titrate)
Vasopressin Onset/Duration of Action - ✅Onset: <5 minutes
Duration: 10-30 minutes
Vasopressin Side Effects - ✅Decrease urine output
Refractory urine dumping in TBI patients upon discontinuation
, Epinephrine Mechanism of Action - ✅Direct-acting alpha and beta agonist. Alpha:
vasoconstriction. Beta-1: positive inotropic, chronotropic, and dromotropic effects. Beta-2:
bronchial smooth muscle relaxation and dilation of skeletal vasculature. Blocks histamine
receptors.
Epinephrine Common Uses - ✅ACLS, anaphylaxis, bradycardia with hypotension, shock, status
asthmaticus
Epinephrine Typical Dosage - ✅1 mg IV push during ACLS. 0.05-0.5 mcg/kg/min
Epinephrine Onset/Duration of Action - ✅Onset: Immediate. Duration: Up to 60 minutes
Epinephrine Side Effects - ✅Increase myocardial oxygen demand, GI hypoperfusion
Dopamine Mechanism of Action - ✅At low doses, selectively stimulates dopamine receptors
causing renal vasodilation & increased renal blood flow; at high doses increases norepinephrine
production, causing increased total peripheral resistance & blood pressure
Dopamine Typical Dosage - ✅Renal Dose: 0.5-2 mcg/kg/min. Low Dose: 5-10 mcg/kg/min.
High Dose: 10-20 mcg/kg/min
Dopamine Onset/Duration of Action - ✅Onset: <5 minutes. Duration: 10 minutes
Dopamine Side Effects - ✅Tachycardia, cardiac dysrhythmias
Dopamine Common Uses - ✅Useful in cardiogenic shock, CHF, renal perfusion
Neosynephrine Mechanism of Action - ✅Pure alpha-adrenergic agonist causing peripheral
vasoconstriction
Neosynephrine Common Uses - ✅Shock, hypotension with tachycardia
Answers|Verified
Norepinephrine Mechanism of Action - ✅Alpha-adrenergic activity: peripheral vasoconstriction
Beta-adrenergic activity: inotropic stimulation of the heart and coronary artery vasodilation
Norepinephrine Common Uses - ✅First line of shock
Norepinephrine Typical Dosing - ✅0.04-0.3 mcg/kg/min
Norepinephrine Onset/Duration of Action - ✅Onset: Immediate
Duration: 1-2 minutes
Norepinephrine Side Effects - ✅Arrhythmias
Severe peripheral vasoconstriction leading to tissue death and limb ischemia
Vasopressin Mechanism of Action - ✅1. Direct stimulation of smooth muscle V1 receptors:
vasoconstriction
2. Acts on V2 receptors in kidneys: water reabsorption
Vasopressin Common Uses - ✅Used with other vasopressors like Levophed
Also used in GI bleeding and Diabetes Insipidus
Vasopressin Typical Dosing - ✅0.03 units/min (TICU does not titrate)
Vasopressin Onset/Duration of Action - ✅Onset: <5 minutes
Duration: 10-30 minutes
Vasopressin Side Effects - ✅Decrease urine output
Refractory urine dumping in TBI patients upon discontinuation
, Epinephrine Mechanism of Action - ✅Direct-acting alpha and beta agonist. Alpha:
vasoconstriction. Beta-1: positive inotropic, chronotropic, and dromotropic effects. Beta-2:
bronchial smooth muscle relaxation and dilation of skeletal vasculature. Blocks histamine
receptors.
Epinephrine Common Uses - ✅ACLS, anaphylaxis, bradycardia with hypotension, shock, status
asthmaticus
Epinephrine Typical Dosage - ✅1 mg IV push during ACLS. 0.05-0.5 mcg/kg/min
Epinephrine Onset/Duration of Action - ✅Onset: Immediate. Duration: Up to 60 minutes
Epinephrine Side Effects - ✅Increase myocardial oxygen demand, GI hypoperfusion
Dopamine Mechanism of Action - ✅At low doses, selectively stimulates dopamine receptors
causing renal vasodilation & increased renal blood flow; at high doses increases norepinephrine
production, causing increased total peripheral resistance & blood pressure
Dopamine Typical Dosage - ✅Renal Dose: 0.5-2 mcg/kg/min. Low Dose: 5-10 mcg/kg/min.
High Dose: 10-20 mcg/kg/min
Dopamine Onset/Duration of Action - ✅Onset: <5 minutes. Duration: 10 minutes
Dopamine Side Effects - ✅Tachycardia, cardiac dysrhythmias
Dopamine Common Uses - ✅Useful in cardiogenic shock, CHF, renal perfusion
Neosynephrine Mechanism of Action - ✅Pure alpha-adrenergic agonist causing peripheral
vasoconstriction
Neosynephrine Common Uses - ✅Shock, hypotension with tachycardia
