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NUR 210 Principles of Pharmacology Elite Quality Assignments | Pass with Confidence

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The University of Hawai‘i at Mānoa offers NURS 210 focusing on a health promotion model of care, assessment, and communication skills. It introduces the nurse's roles, code of ethics, and evidence-based practice.

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NUR 210 Principles of Pharmacology Elite Quality
Assignments | Pass with Confidence
selectivity - A "selective" drug binds to a primary and predictable site, creating one
desired effect. A "non-selective" drug can bind to many different and unpredictable receptor
sites with potential side effects.

stage 1: the interim between consciousness and sleep - when sleep is interrupted, what
stage does the sleep cycle restart?

NREM sleep - encompasses all sleep stages except for REM sleep

insomnia - the inability to fall asleep

- affects 10-30% of Americans

- more common in female patients

- tx: sedative hypnotics

action of benzodiazepines - this class of medication is used to treat sleep disorders
(insomnia) and anxiety

- interacts with neurotransmitter GABA to reduce neuron excitability

action of non benzodiazepines - this class of medications inhibits neurotransmitters and
causes CNS depression

- the duration of action is 6-8 hours

- treats insomnia short term ( less than 10 days)

- older adults are given smaller doses

depression

tolerance

dependence

hypotension - adverse reactions of benzodiazepine drugs

contraindications - If a patient has respiratory depression or an allergy they should not
take benzodiazepines. Respiratory depression and a benzodiazepine allergy are
considered____________?

,non pharmalogical measures first

avoid other CNS depressants, OTC sleep aids, and benzos

take at bedtime (sedative)

do not drive while medicated (sedative)

report feelings of hangover (not enough sleep) - what teaching is needed for patient's
who take non benzodiazepine medications such as Ambien?

general anesthesia - involves the total loss of body sensation and consciousness induced
by anesthetic agents administered primarily by inhalation or intravenous injection

local anesthesia - causes the loss of sensation in a limited area by injecting an anesthetic
solution near that area

regional anesthesia - Temporary interruption of nerve conduction, is produced by
injecting an anesthetic solution near the nerves to be blocked

- such as an epidural

balanced anesthesia - use of several different types of drugs to achieve the quickest,
most effective anesthesia with the fewest adverse effects

- involves using less general anesthesia

- premedication with an opioid analgesic or benzo (versed/midazolam)

- with an anticholinergic (to prevent aspiration and dry secretions)

- a short acting barbituate

- an inhaled gas

- muscle relaxant

Midazolam (Versed) - Class: Benzodiazepine

Indications: the induction and maintenance of anesthesia or conscious sedation for minor
surgery or procedures

- patients are sedated and relaxed but responsive to commands

Adverse effects: respiratory and cardiovascular depression

Contraindications: cardiopulmonary disease

, Nursing Considerations:

- assess level of sedation during and for 2-6 hours following

- monitor blood pressure, pulse, respirations during IV administration

- The antidote for overdose is flumazenil

spinal and epidural anesthesia - is administered into the cerebral fluid or epidural area of
the spine that corresponds with the area being treated

- commonly used for caesarian sections

- common side effect: headache

- adverse reactions: hypotension and respiratory distress

monitory safety

observe urine output

monitor vital signs - what are the nursing interventions for anesthetics

topical anesthetics - block sensation of pain by numbing the skin layers and mucous
membranes

- benzocaine

- lidocaine

contraindications of non benzodiazepines - if a patient has an allergy to benzodiazepines,
respiratory depression, severe renal or liver disease, a child, or an older adult, they should not
take Ambien. The following are contraindications of what medicaiton class?

lethargy

drowsiness

confusion (older adults)

memory impairment - side effects of benzodiazepines

drowsiness

lethargy

dizziness

memory impairment - side effects of non benzodiazepines
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