,Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch) 1
Table of Contents
Table of Contents 1
Chapter 01 - Introduction to Drugs 3
Chapter 02 - Drugs and the Body 20
Chapter 03 - Toxic Effects of Drugs 37
Chapter 04 - The Nursing Process in Drug Therapy and Patient Safety 54
Chapter 05 - Dosage Calculations 71
Chapter 06 - Challenges to Effective Drug Therapy 86
Chapter 07 - Introduction to Cell Physiology 103
Chapter 08 - Antiinfective Agents 120
Chapter 09 - Antibiotics 138
Chapter 10 - Antiviral Agents 155
Chapter 11 - Antifungal Agents 172
Chapter 12 - Antiprotozoal Agents 188
Chapter 13 - Anthelmintic Agents 204
Chapter 14 - Antineoplastic Agents 220
Chapter 15 - Introduction to the Immune Response and Inflammation 237
Chapter 16 - Antiinflammatory, Antiarthritis, and Related Agents 254
Chapter 17 - Immune Modulators 270
Chapter 18 - Vaccines and Sera 287
Chapter 19 - Introduction to Nerves and the Nervous System 304
Chapter 20 - Anxiolytic and Hypnotic Agents 320
Chapter 21 - Antidepressant Agents 337
Chapter 22 - Psychotherapeutic Agents 354
Chapter 23 - Antiseizure Agents 371
Chapter 24 - Antiparkinsonism Agents 388
Chapter 25 - Muscle Relaxants 404
Chapter 26 - Narcotics, Narcotic Antagonists, and Antimigraine Agents 420
Chapter 27 - General and Local Anesthetic Agents 436
Chapter 28 - Neuromuscular Junction Blocking Agents 453
Chapter 29 - Introduction to the Autonomic Nervous System 470
Chapter 30 - Adrenergic Agonists 487
Chapter 31 - Adrenergic Antagonists 503
Chapter 32 - Cholinergic Agonists 520
Chapter 33 - Anticholinergic Agents 536
Chapter 34 - Introduction to the Endocrine System 553
Chapter 35 - Hypothalamic and Pituitary Agents 569
Chapter 36 - Adrenocortical Agents 585
Chapter 37 - Thyroid and Parathyroid Agents 602
Chapter 38 - Agents to Control Blood Glucose Levels 619
Chapter 39 - Introduction to the Reproductive System 636
Chapter 40 - Drugs Affecting the Female Reproductive System 653
Chapter 41 - Drugs Affecting the Male Reproductive System 669
Chapter 42 - Introduction to the Cardiovascular System 685
Chapter 43 - Drugs Affecting Blood Pressure 702
Chapter 44 - Agents for Treating Heart Failure 719
Chapter 45 - Antiarrhythmic Agents 735
Chapter 46 - Antianginal Agents 752
Chapter 47 - Lipid-Lowering Agents 768
Chapter 48 - Drugs Affecting Blood Coagulation 785
Chapter 49 - Drugs Used to Treat Anemias 801
Chapter 50 - Introduction to the Renal System 817
,Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch) 2
Chapter 51 - Diuretic Agents 833
Chapter 52 - Drugs Affecting the Urinary Tract and the Bladder 849
Chapter 53 - Introduction to the Respiratory System 866
Chapter 54 - Drugs Acting on the Upper Respiratory Tract 883
Chapter 55 - Drugs Acting on the Lower Respiratory Tract 900
Chapter 56 - Introduction to the Gastrointestinal System 917
Chapter 57 - Drugs Affecting Gastrointestinal Secretions 933
Chapter 58 - Drugs Affecting Gastrointestinal Motility 949
Chapter 59 - Antiemetic Agents 965
,Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch) 3
Chapter 01 - Introduction to Drugs
A nurse working in radiology administers iodine to a patient who is having a computed tomography(CT)
scan. The nurse working on the oncology unit administers chemotherapy to patients who have
cancer. At the Public Health Department, a nurse administers a measles-mumps-rubella (MMR)
vaccine to a 14-month-old child as a routine immunization. Which branch of pharmacology best
describes the actions of all three nurses?
Pharmacoeconomics
Pharmacotherapeutics
Pharmacodynamics
Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical
pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses of
drugs to treat, prevent, and diagnose disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administering a drug to help treat a disease.
Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves how a
drug affects the body and pharmacokinetics is how the body acts on the body.
A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 hours as neededfor
pain in a motor vehicle accident victim. The nurse is aware this drug has a high abuse potential.
Under what category would morphine be classified?
Schedule I
Schedule II
Schedule III
Schedule IV
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs because of severe dependence
,Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch) 4
liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III drugs
have a lesser abuse potential than II and an accepted medical use. Schedule IV drugs have low abuse
potential and limited dependence liability.
When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
Working with animals who are given experimental drugs
Choosing appropriate patients to be involved in the drug study
Monitoring and observing patients closely for adverse effects
Conducting research to determine effectiveness of the drugAns: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which patients are asked to record
any symptoms they experience while taking the drugs. Nurses may be responsible for helping collect
and analyze the information to be shared with the Food and Drug Administration (FDA) but would not
conduct research independently because nurses do not prescribe medications. Use of animals in drug
testing is done in the preclinical trials. Select patients who are involved in phase II studies to participate
in studies where the participants have the disease the drug is intended to treat. These patients are
monitored closely for drug action and adverse effects. Phase I studies involve healthy human volunteers
who are usually paid for their participation. Nurses may observe for adverse effects and toxicity.
What concept is considered when generic drugs are substituted for brand name drugs?
Bioavailability
Critical concentration
Distribution
Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is available to
act on body cells. Binders used in a generic drug may not be the same as those used in the brand name
drug. Therefore, the way the body breaks down and uses the drug may differ, which may eliminate a
generic drug substitution. Critical concentration is the amount of a drug that is needed to cause a
therapeutic effect and should not differ between generic and brand name medications. Distribution is
the phase of pharmacokinetics, which involves the movement of a drug to the body’s tissues and is the
, Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch) 5
same in generic and brand name drugs. A drug’s half-life is the time it takes for the amount of drug to
decrease to half the peak level, which should not change when substituting a generic medication.
A nurse is assessing the patient’s home medication use. After listening to the patient list current
medications, the nurse asks what priority question?
Do you take any generic medications?
Are any of these medications orphan drugs?
Are these medications safe to take during pregnancy?
Do you take any over-the-counter medications?
Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-counter medications because
patients may not consider them important. The patient is unlikely to know the meaning of orphan drugs
unless they too are health care providers. Safety during pregnancy, use of a generic medication, or
classification of orphan drugs are things the patient would be unable to answer but could be found in
reference books if the nurse wishes to research them.
After completing a course on pharmacology for nurses, what will the nurse know?
Everything necessary for safe and effective medication administration
Current pharmacologic therapy; the nurse will not require ongoing education for 5 years.
General drug information; the nurse can consult a drug guide for specific drug information.
The drug actions that are associated with each classification of medicationAns: C
Feedback:
After completing a pharmacology course nurses will have general drug information needed for safe and
effective medication administration but will need to consult a drug guide for specific drug information
before administering any medication. Pharmacology is constantly changing, with new drugs entering
the market and new uses for existing drugs identified. Continuing education in pharmacology is
essential to safe practice. Nurses tend to become familiar with the medications they administer most
often, but there will always be a need to research new drugs and also those the nurse is not familiar with
because no nurse knows all medications.
Table of Contents
Table of Contents 1
Chapter 01 - Introduction to Drugs 3
Chapter 02 - Drugs and the Body 20
Chapter 03 - Toxic Effects of Drugs 37
Chapter 04 - The Nursing Process in Drug Therapy and Patient Safety 54
Chapter 05 - Dosage Calculations 71
Chapter 06 - Challenges to Effective Drug Therapy 86
Chapter 07 - Introduction to Cell Physiology 103
Chapter 08 - Antiinfective Agents 120
Chapter 09 - Antibiotics 138
Chapter 10 - Antiviral Agents 155
Chapter 11 - Antifungal Agents 172
Chapter 12 - Antiprotozoal Agents 188
Chapter 13 - Anthelmintic Agents 204
Chapter 14 - Antineoplastic Agents 220
Chapter 15 - Introduction to the Immune Response and Inflammation 237
Chapter 16 - Antiinflammatory, Antiarthritis, and Related Agents 254
Chapter 17 - Immune Modulators 270
Chapter 18 - Vaccines and Sera 287
Chapter 19 - Introduction to Nerves and the Nervous System 304
Chapter 20 - Anxiolytic and Hypnotic Agents 320
Chapter 21 - Antidepressant Agents 337
Chapter 22 - Psychotherapeutic Agents 354
Chapter 23 - Antiseizure Agents 371
Chapter 24 - Antiparkinsonism Agents 388
Chapter 25 - Muscle Relaxants 404
Chapter 26 - Narcotics, Narcotic Antagonists, and Antimigraine Agents 420
Chapter 27 - General and Local Anesthetic Agents 436
Chapter 28 - Neuromuscular Junction Blocking Agents 453
Chapter 29 - Introduction to the Autonomic Nervous System 470
Chapter 30 - Adrenergic Agonists 487
Chapter 31 - Adrenergic Antagonists 503
Chapter 32 - Cholinergic Agonists 520
Chapter 33 - Anticholinergic Agents 536
Chapter 34 - Introduction to the Endocrine System 553
Chapter 35 - Hypothalamic and Pituitary Agents 569
Chapter 36 - Adrenocortical Agents 585
Chapter 37 - Thyroid and Parathyroid Agents 602
Chapter 38 - Agents to Control Blood Glucose Levels 619
Chapter 39 - Introduction to the Reproductive System 636
Chapter 40 - Drugs Affecting the Female Reproductive System 653
Chapter 41 - Drugs Affecting the Male Reproductive System 669
Chapter 42 - Introduction to the Cardiovascular System 685
Chapter 43 - Drugs Affecting Blood Pressure 702
Chapter 44 - Agents for Treating Heart Failure 719
Chapter 45 - Antiarrhythmic Agents 735
Chapter 46 - Antianginal Agents 752
Chapter 47 - Lipid-Lowering Agents 768
Chapter 48 - Drugs Affecting Blood Coagulation 785
Chapter 49 - Drugs Used to Treat Anemias 801
Chapter 50 - Introduction to the Renal System 817
,Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch) 2
Chapter 51 - Diuretic Agents 833
Chapter 52 - Drugs Affecting the Urinary Tract and the Bladder 849
Chapter 53 - Introduction to the Respiratory System 866
Chapter 54 - Drugs Acting on the Upper Respiratory Tract 883
Chapter 55 - Drugs Acting on the Lower Respiratory Tract 900
Chapter 56 - Introduction to the Gastrointestinal System 917
Chapter 57 - Drugs Affecting Gastrointestinal Secretions 933
Chapter 58 - Drugs Affecting Gastrointestinal Motility 949
Chapter 59 - Antiemetic Agents 965
,Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch) 3
Chapter 01 - Introduction to Drugs
A nurse working in radiology administers iodine to a patient who is having a computed tomography(CT)
scan. The nurse working on the oncology unit administers chemotherapy to patients who have
cancer. At the Public Health Department, a nurse administers a measles-mumps-rubella (MMR)
vaccine to a 14-month-old child as a routine immunization. Which branch of pharmacology best
describes the actions of all three nurses?
Pharmacoeconomics
Pharmacotherapeutics
Pharmacodynamics
Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are involved with clinical
pharmacology or pharmacotherapeutics, which is a branch of pharmacology that deals with the uses of
drugs to treat, prevent, and diagnose disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administering a drug to help treat a disease.
Pharmacoeconomics includes any costs involved in drug therapy. Pharmacodynamics involves how a
drug affects the body and pharmacokinetics is how the body acts on the body.
A physician has ordered intramuscular (IM) injections of morphine, a narcotic, every 4 hours as neededfor
pain in a motor vehicle accident victim. The nurse is aware this drug has a high abuse potential.
Under what category would morphine be classified?
Schedule I
Schedule II
Schedule III
Schedule IV
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II drugs because of severe dependence
,Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch) 4
liability. Schedule I drugs have high abuse potential and no accepted medical use. Schedule III drugs
have a lesser abuse potential than II and an accepted medical use. Schedule IV drugs have low abuse
potential and limited dependence liability.
When involved in phase III drug evaluation studies, what responsibilities would the nurse have?
Working with animals who are given experimental drugs
Choosing appropriate patients to be involved in the drug study
Monitoring and observing patients closely for adverse effects
Conducting research to determine effectiveness of the drugAns: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in which patients are asked to record
any symptoms they experience while taking the drugs. Nurses may be responsible for helping collect
and analyze the information to be shared with the Food and Drug Administration (FDA) but would not
conduct research independently because nurses do not prescribe medications. Use of animals in drug
testing is done in the preclinical trials. Select patients who are involved in phase II studies to participate
in studies where the participants have the disease the drug is intended to treat. These patients are
monitored closely for drug action and adverse effects. Phase I studies involve healthy human volunteers
who are usually paid for their participation. Nurses may observe for adverse effects and toxicity.
What concept is considered when generic drugs are substituted for brand name drugs?
Bioavailability
Critical concentration
Distribution
Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the systemic circulation and is available to
act on body cells. Binders used in a generic drug may not be the same as those used in the brand name
drug. Therefore, the way the body breaks down and uses the drug may differ, which may eliminate a
generic drug substitution. Critical concentration is the amount of a drug that is needed to cause a
therapeutic effect and should not differ between generic and brand name medications. Distribution is
the phase of pharmacokinetics, which involves the movement of a drug to the body’s tissues and is the
, Test Bank - Focus on Nursing Pharmacology (8th Edition by Karch) 5
same in generic and brand name drugs. A drug’s half-life is the time it takes for the amount of drug to
decrease to half the peak level, which should not change when substituting a generic medication.
A nurse is assessing the patient’s home medication use. After listening to the patient list current
medications, the nurse asks what priority question?
Do you take any generic medications?
Are any of these medications orphan drugs?
Are these medications safe to take during pregnancy?
Do you take any over-the-counter medications?
Ans: D
Feedback:
It is important for the nurse to specifically question use of over-the-counter medications because
patients may not consider them important. The patient is unlikely to know the meaning of orphan drugs
unless they too are health care providers. Safety during pregnancy, use of a generic medication, or
classification of orphan drugs are things the patient would be unable to answer but could be found in
reference books if the nurse wishes to research them.
After completing a course on pharmacology for nurses, what will the nurse know?
Everything necessary for safe and effective medication administration
Current pharmacologic therapy; the nurse will not require ongoing education for 5 years.
General drug information; the nurse can consult a drug guide for specific drug information.
The drug actions that are associated with each classification of medicationAns: C
Feedback:
After completing a pharmacology course nurses will have general drug information needed for safe and
effective medication administration but will need to consult a drug guide for specific drug information
before administering any medication. Pharmacology is constantly changing, with new drugs entering
the market and new uses for existing drugs identified. Continuing education in pharmacology is
essential to safe practice. Nurses tend to become familiar with the medications they administer most
often, but there will always be a need to research new drugs and also those the nurse is not familiar with
because no nurse knows all medications.
